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TIMP2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Bos taurus
Length
220 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
24.355 kDa
Sequence
MGAAARSLPLAFCLLLLGTLLPRADACSCSPVHPQQAFCNADIVIRAKAVNKKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDQDIEFIYTAPAAAVCGVSLDIGGKKEYLIAGKAEGNGNMHITLCDFIVPWDTLSATQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: TIMP2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Canis lupus familiaris
Length
220 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
24.297 kDa
Sequence
MGAAARSLRLALGLLLLATLPRPADACSCSPVHPQQAFCNADVVIRAKAVSVKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDIGGKKEYLIAGKAEGNGKMHITLCDFIVPWDTLSSTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: TIMP2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Cavia porcellus
Length
220 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
24.318 kDa
Sequence
MGATARSLRLALGLLLLGTLPRGADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: TIMP2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Gallus gallus
Length
220 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
24.313 kDa
Sequence
MPGAALPSLLAWLAVLLLGRARPADACSCSPIHPQQAFCNADVVIRAKRVSAKEVDSGNDIYGNPIKRIQYEVKQIKMFKGPDQDIEFIYTAPSTEVCGQPLDTGGKKEYLIAGKSEGDGKMHITLCDLVATWDSVSPTQKKSLNQRYQMGCECKISRCLSIPCFVSSSDECLWTDWAMEKIVGGRQAKHYACIKRSDGSCAWYRGMAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: TIMP2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Homo sapiens
Length
220 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
24.399 kDa
Sequence
MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: TIMP2

Gene
Timp2
Protein
Metalloproteinase inhibitor 2
Organism
Mus musculus
Length
220 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
24.328 kDa
Sequence
MGAAARSLRLALGLLLLASLVRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: Timp2

Gene
Timp2
Protein
Metalloproteinase inhibitor 2
Organism
Rattus norvegicus
Length
220 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
24.356 kDa
Sequence
MGAAARSLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: Timp2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Cricetulus longicaudatus
Length
196 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
21.941 kDa
Fragment
single
Sequence
RACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: TIMP2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Oryctolagus cuniculus
Length
194 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
21.849 kDa
Sequence
CSCSPVHPQQAFCNADIVIRAKAVNKKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDQDIEFIYTAPSSAVCGVSLDIGGKKEYLIAGKAEGNGNMHITLCDFIVPWDTLSATQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINRHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Protein
Metalloproteinase inhibitor 2: TIMP2

Gene
TIMP2
Protein
Metalloproteinase inhibitor 2
Organism
Equus caballus
Length
91 amino acids
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them.
Similarity
Belongs to the protease inhibitor I35 (TIMP) family.
Mass
9.998 kDa
Fragment
single
Sequence
KAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKADGNGKMHITLCDFIVPWDTLST
Protein
Metalloproteinase inhibitor 2: TIMP2