themis

Protein THEMIS

675 amino acids

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity).

Belongs to the themis family.

76.625 kDa

MAQTLQEFTHALEEKHLPRVLHIQSGIYYQGCVYEVFGQECSLSTGDLLKVTEITISRFNALTSSSTEIQLPVEYPGLFKLMADSQPYRSIQEIADSLKIGPQRVAQPVFLSAVDVDLEPGLVLRRRDSFRITAVEWSCGRVHCELLHREPPICFSLSFCQQGPFSECQDHQCYTLKEIADWKIPRGRKRSVVEVKAPAKKNFLFSGLLENVCGELLLTPVYELKAISRLSEKVLLIPSNLDVEVVDVTEQYDCDSFVQPLSLMDVYKRPPQFFPVLAKLSSENHFRLSPDLESLFQSKEVIIHHPFKAKRILASEMCQESARHFLIPESYNGRFKRRPRQFSTAYDLERARSETEEIRVVATKDFETVYSGLASVQAGEEFIVTKGQSCAVSHNGTEKVADTFECVKVKAEGKEPVRLPMCLEGGFMELVKDKRQYTIAEICRWFPLPFNVKVSVRDLSLKADILAGTPSLHIEEEISDPCVLVSNTDLSDFREVPVNRTDLIFNVKQRWDGESPKFSVKSAIEEISEDCYYTIRRYAIATITPPPRPPKKPKDPPPRPPKTSRSESTNSESSSCSPKTLHVEPFKQDGLLQCCDSRNGNEQKIPISPVTLPRPSLQKARAKGRSLDDISMDKHAASDNDVHDYEYIDEEQLDNIRRTYQEQQINTKAKPSHTI

THEMIS

Protein THEMIS

641 amino acids

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

Belongs to the themis family.

73.132 kDa

MALSLEEFIHSLDLRTLPRVLEIQSGFYFEGSIYEMFGNECCLSTGEVIKITDLKIKKIMAEICEHVEGCVSPQSFELPMNFPGLFKIVADTTPYLTMEEITKANHIRPSRPNHPCFYHQKDIKLENLIIKKGERIMLNSVEEINGEIMVNCSVLRNHQNHSFTLPLSQEGEFYECEDEHIYTLKEIIQWKIPKNRTRTVILTGFSAKWDSTNPFPRGFYGAVILKPVYEIQAVMKFRKDIVRILPSLDVEVKDITDSYDANWFLQVLSTQDLYEMANKQFPIVAEVIEAPQGNQLPISILQPGKTIVIHKKCQASKILASEIRSNSSKRHFLIPTSYKGKFKRRPREFPTAYDLEIAKSEKEPLHVVATKAFHSPFEELSSVSVGDEFLVHHSQTTEVLCEGIKKVMDGLACEKILKNSREVALLPLYMDGGFVEVIHDKKLYQISELCAQFRLPFNVKVSVRDLFIEKDILAAIPGLQLEESITNSYLLISDLANPKKCWEIPVGRVNMTVQLVNNFSGDTGSFLVSTLVEEITEEQYYLIRRYEKSFLHPPPRPPKHPSVEKIELTPLSLAKQKTVNLPKSPKSVHVDRSKKLYSNQAGLDSKVPAGCQNDLADLEKEKRKTEATAVTEIFKTEEHKK

THEMIS

Protein THEMIS

641 amino acids

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

Belongs to the themis family.

73.452 kDa

MALSLEEFVHSLDLRTLPRVLEIQAGIYLEGSIYEMFGNECCFSTGEVIKITGLKVKKIIAEICEQIEGCESLQPFELPMNFPGLFKIVADKTPYLTMEEITRTIHIGPSRLGHPCFYHQKDIKLENLIIKQGEQIMLNSVEEIDGEIMVSCAVARNHQTHSFNLPLSQEGEFYECEDERIYTLKEIVEWKIPKNRTRTVNLTDFSNKWDSTNPFPKDFYGTLILKPVYEIQGVMKFRKDIIRILPSLDVEVKDITDSYDANWFLQLLSTEDLFEMTSKEFPIVTEVIEAPEGNHLPQSILQPGKTIVIHKKYQASRILASEIRSNFPKRHFLIPTSYKGKFKRRPREFPTAYDLEIAKSEKEPLHVVATKAFHSPHDKLSSVSVGDQFLVHQSETTEVLCEGIKKVVNVLACEKILKKSYEAALLPLYMEGGFVEVIHDKKQYPISELCKQFRLPFNVKVSVRDLSIEEDVLAATPGLQLEEDITDSYLLISDFANPTECWEIPVGRLNMTVQLVSNFSRDAEPFLVRTLVEEITEEQYYMMRRYESSASHPPPRPPKHPSVEETKLTLLTLAEERTVDLPKSPKRHHVDITKKLHPNQAGLDSKVLIGSQNDLVDEEKERSNRGATAIAETFKNEKHQK

Themis

Protein THEMIS

636 amino acids

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

Belongs to the themis family.

72.78 kDa

MALSLEEFVYSLDLRTLPRVLEIQSGIYFEGSVYEMFGNECCLSTGEVIKITGLKIKKMMAEICEGAIGGCESQKPFELPMNFPGLFKVMADKTPYLSIEEITRTVNIGPSRLGHPCFYHLKDIKLENLIIKQGEPIRFNSVEEINGETLVNCGVVRNHQSHSFTLPLSQEGEFYECEDEHIYTLKEIVEWKIPKNRTRTVKLTDFSNKWDSTNPFPEDFYGTLILKPVYEIQGVLKFQKDIVRILPSLDVEVKDITDSYDANWFLQLLSTDDLFEMTSKEFPVVAEVVEISQGNHLPQSILQREKTIVIHKKYQASRILASEIRSNFPKRHFLIPISYKGKFKRRPREFPTAYDLQIAKSRKETLHVVATKAFHTLHKELSPVSVGDQFLVHHSETTEVVFEGTRKVNVLTCEKVLNKTREDAQLPLYMEGGFVEVIHDKKQYQISELCTQFCWPFNVKVAVRDLSIKDDILAATPGLQLEEDITDSYLLISDFANPEECWEIPMSRLNMTVRLVNGSSLPADAGLLQVRSFVEEITEEQYYMMRRYESSLSHPPPRPPKHPSAEEMKLTLLSLAEERTINLPKSLKSHHVDRPKKLPSDESGQDSRAPVGFQNDVADVERQKSKHGPLQPQAPL