About Products Protein Database Contact

TECPR1

Gene
TECPR1
Protein
Tectonin beta-propeller repeat-containing protein 1
Organism
Gallus gallus
Length
1173 amino acids
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes. Binds phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes (By similarity).
Similarity
Belongs to the TECPR1 family.
Mass
131.812 kDa
Sequence
MSSSLLWAVDIFGRVYTLSTVGQYWELCKDTQLEFKRVSAVKQCCWGIACDHQVYTYVFSGDVPIRYQEETYENQRWNPVGGFCEKLMPSDRWQWSDVSGLKHQQLDSFTLPSPHWEWESDWYVDENIGGEPTEKGGWTYAIDFPSTYTKDKKWNSCVRRRRWIRYRRYKSRDVWAKITSHDDPERLPDPFNDISIGGWEITDEPLGRLSVWAVSLQGRVWYRENVCHHNPEGSTWSLISTPGEVAQISCGSYDLLWATLWEGQAIVREGIDRNNPQGISWSTVESPSSDNGIMHVSVGVDVVWCITKDRKVWFRRGVNSHNPCGTSWIEMVGEMMMVNVGLNNQVWGIGCDDRTIYFRQGVTPSELSGKMWKAIVCGRESDRSQTGSSTSLLSAGCFFTDDIQNQTNTVIQGDADTSSDTELSSIPTNLSSTPPMGAAASSASSTGSQAAGAPASVTVDPLDSDQGEAPAASASDEKAHLESRKSTNPTPSTELQWTNIDLKEAHRHAVLSVSTFTETSSLSSLGMFSVGAEEQYGADEHPLWAWVSGGGCLVDLHSPLKWFAVPSGLSSSVQSLSLSITPAQTAAWRKQIFQQLSERTKRELENFRHYEQAVEQSVWVKTGMLQWWRNWKPHKWMDVRVALEQFTGSDGMRDSILFIYYMYHEEKKYIHVFLNEVTIIAEVLKEGKHSFALYTPERTKQRWPICLAATTEQEMHDWLSLLTMSCCESRRIQGPPSHHAIWSVSCKGDIFVSEPSPELEAEPHPMPCDQMFWRQVGGHLRLVECNNRGIVWGIGYDHTVWVYTGGYGGGFIQGLASSADNIYTQSDVKCVYIYENQRWNPVTGYSSRGLPTDRYMWSDASGLQECTKANTKPPSPQWSWVSDWYIDFSTSGGTDREGWQYAADFPASYHGHKTMKDFVRRRRWARKCKIVTNGPWLEVPPVTLWDISIIPSSDADDEESVALWAISDKGDVLCRLGVTQQNPAGTSWLHVGTDQPFVSISVGAFFQVWAVARDGSAFYRGSVSPKKPAGDCWYHIPSPQKQKLKQVSVGRTSVFVLDKNGNLWYRQGITPSYPQGSAWDHVSNNIRKMSVGPLDQVWVIADKVQGSHGLSCGTVCHRTGVQPMEPKGLAWDYGIGGGWEHVTVRGNASQAPRGTVPSESPPEPMESEGRVMC
Protein
Tectonin beta-propeller repeat-containing protein 1: TECPR1

Gene
tecpr1
Protein
Tectonin beta-propeller repeat-containing protein 1
Organism
Xenopus tropicalis
Length
1173 amino acids
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes. Binds phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes (By similarity).
Similarity
Belongs to the TECPR1 family.
Mass
131.493 kDa
Sequence
MPSTVLWATDIFGKVFTLSTDGQQWAPCKNGHVEFKRVSAVRSCCWGVGCNHQIYLYVHASDLPIRYQEETYENQRWNPVDGYCEKLLPSDRWQWSDVTGLRHQQLESFMLPSPHWEWESDWYVDENIGGEPTEKGGWTYAIDFPATYTKDKKWNSCVRRRRWIRYRKYKSRNTWAKIPSHEDNKKLPDPFNDITVGGWEITDEPVGRLSVWAASLQGKVWYREDVCQNIPEGSSWTELETPSEVIQISCGPNDLLWASLWEGQAMVREGINRNNPKGSSWTIVEAPTPENGIMHVSVGVNVVWAVTKDRKVWFRRGVNSHNPCGTGWIEMVGEMAMVDVGLNDQVFGVGYEDRAVYFRQGVTPSELSGKAWKSIVVPRGNERSNSESPNSLLSAGCFFGDEIKEHSDSPIPSDIESSSEPEQSAVQENSSDSSEPADVGPSQQDEPKDEELSAVLELDGQQKAGSSLSKDSGEDSAHSAGPVPKAGAPKWTSIDLLEARINPARASGDMTGLSTLGIFTAGEEESFVCETHPLWTWVSGGGCLVESHTPLKWFTLQTGLSASMQSLSLSITPAHTAAWRKQIFDQLSERSKRELDSFRHYEQAVEQSVWVKTGALQWYRDWKPNKWIDVRVALEQLTGTDGSRDSILFVYYTHGEEKKYIHIFLNEVTILVPVANEAKHSFAIYTPEKTKQRWPIRLAAATEQEMHDWLVLLSMSCYESRKLQGAPSSQAIWSVTCKGDIFVSEPKADLESVTNGRSCDQMFWRQIGGHLRMVESSSNGVVWGLGYDHTAWVYTGGYGGGFFPGIASSTDNIFPQTDTKCVYIYENQRWNPITGYSSTGLPTDRYMWSDASGLQECTKTNTKPPSPQWTWVSDWYIDFNVPGGTDREGWQFAADFPASYHGYKTIKDFVRRRRWARKCRIVTSGPWLEVPPICLWDISISPSSGAHNSESIALWAISNKGDVLCRLGVTKQSPSGSSWLHVGTDQPFISVSVGGCLQVWAIARDGSAFYRGSVSPAQPAGDCWYHIPSPHKQKLQQVSVGHTSVFVVDENGNLWFRHGITPTYPQGTTWEHMSNNIRKVSVGPLDQIWVIADKVQGSHSLSCGTVCHRLGVQPMQLKGHSWDYGIGGGWEHITVRGNRADMAKTLQPKENATEKPDPQEENGESAFSHIANC
Protein
Tectonin beta-propeller repeat-containing protein 1: tecpr1

Gene
Tecpr1
Protein
Tectonin beta-propeller repeat-containing protein 1
Organism
Mus musculus
Length
1166 amino acids
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity).
Similarity
Belongs to the TECPR1 family.
Mass
130.266 kDa
Sequence
MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQCCWGIAGDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWPWSDVSGLQHRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDSWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVETPGEVVQISCGPHDLIWATLWEGQALVREGVCRNNPKGSYWSMVEPPGSENGIMHVSAGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPSELSGKTWKAIVVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASLEVERQGPEQPLPKEALDNSTNLKGSLSKGHETSGNTDHSTENACLTEGKEKAPETSRSDECRGPASTPAELPWTNIDLKEPKKVSNQPAAGFPETAGLSSLGLFPMGMEEPYGADDHPLWAWVSGGACAVEAGSTLKWFTIQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEARERLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRFMWSDVTGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPITLSDVSIIPESAHADGRGHNVALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGGWDHISVRANATRVPRNMSRDREARGPGPVCC
Protein
Tectonin beta-propeller repeat-containing protein 1: Tecpr1

Gene
Tecpr1
Protein
Tectonin beta-propeller repeat-containing protein 1
Organism
Rattus norvegicus
Length
1166 amino acids
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity).
Similarity
Belongs to the TECPR1 family.
Mass
130.187 kDa
Sequence
MPTSMLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQCCWGIACDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPYWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDTWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYRENVSHPNPEGSSWSLVDTPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGNSWSIVEPPGSENGIMHVSAGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPSELSGKTWKAIVVGRESDRSHSGSSSSLLSAGCFFGEEVRGSGTESAPSDTDASSEVERQGPERSLPKESLDNSRNLKGSSSKGHESTRNTEDPMENACLAEGQAKAPKTSGPDECHGPAPTPAELPWTNIDLKEPKKASNQPAAGFPETSGLSSLGLFPMGMEEPYGADDHPLWAWVSGGGCAVEAGSALKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAATTEQDMNDWLTLLSLSCCESRKVHGRPSLQAIWSVTCKGDIFVSEPSPDLEAHEHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDVTGLQECTKAGTKPPSLQWTWVSDWYVDFSVLGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPESADANGRGHNIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGGWDHISVRANATRAPRNMSRDQEAHGPGPVCC
Protein
Tectonin beta-propeller repeat-containing protein 1: Tecpr1

Gene
TECPR1
Protein
Tectonin beta-propeller repeat-containing protein 1
Organism
Pongo abelii
Length
1165 amino acids
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity).
Similarity
Belongs to the TECPR1 family.
Mass
129.774 kDa
Sequence
MPNSVLWAVDLFGRVYTLSTAGQYWELCKDSQLEFKRVSATTQCCWGIACDNQVYVYVCASDVPIRRREEAYENQRWNPVGGFCEKLLLSDRWAWSDVSGLQHRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAIDFPATYTKEKKWNSCVRRRKWIRYRRYKSRDIWAKIPSKDDPKELPDPFNDLSVGGWEIAEEPVGRLSVWAVSLQGKVWYREDVSHSNPEGSSWSLLDTPGEVVQISCGPHDLLWATLWEGQALVREGINRSNPKGSSWSIVEPPGSDNGIMHVSVGVSVVWAVTKDWKVWFRRGINSHNPCGTSWIEMVGEMTMVNVGMNDQVWGIGCEDRAVYFRQGVTPSELSGKTWKAIVAARECDRSHSGSSSSLLSAGCFFGDEVRGSGESAPSDTDASSEVERPGPGQTLPAEPLDDSKNAMENSASGPGAGRTTEDTVEDACPAEGSREARPNTHPGPATTPAELPWTNIDLKEPKKVPSHSAAGFPETTSLSSLGLFPLGLEEPYGVDDHPLRAWVSGGGCMVEACAVPRWFTVQAGLSSSVHMLSLSITPAQTAAWRKQIFQQLTERTKRELENFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVHEEKKYIHIFLNEVVALVPVLNETKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVQGRPSPQAIWSITCKGDIFVSEPSPDLEAHEHPLPCDQMFWRQMGGHLRMVEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYMQSDVKCVHIYENQRWNPVTGYTSRGLPTDRYMWSDASGLQECTKAGTKPPSLQWAWVSDWFVDFSVPGGTDQEGWQYASDFPASYHGSKTMKDFVRRRCRARKCKLVTSGPWLEVPPIALRDVSIIPESPGAEGSGHSIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFTSISIGACYQVWAVARDGSTFYRGSVYPSQPAGDCWYHIPSPPRQRLKQVSVGQTSVYALDENGNLWYRQGITPSYPQGSSWEHVSNNVCRVSVGPLDQVWVIADKVQGSHSLSRGTVCHRTGVQPHEPKGHGWDYGIGGGWDHISVRANATRAPRSSSQEQEPSAPPEAHDPVCC
Protein
Tectonin beta-propeller repeat-containing protein 1: TECPR1

Gene
TECPR1
Protein
Tectonin beta-propeller repeat-containing protein 1
Organism
Homo sapiens
Length
1165 amino acids
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
Similarity
Belongs to the TECPR1 family.
Mass
129.696 kDa
Sequence
MPNSVLWAVDLFGRVYTLSTAGQYWEMCKDSQLEFKRVSATTQCCWGIACDNQVYVYVCASDVPIRRREEAYENQRWNPMGGFCEKLLLSDRWGWSDVSGLQHRPLDRVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAIDFPATYTKDKKWNSCVRRRKWIRYRRYKSRDIWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHSNPEGSSWSLLDTPGEVVQISCGPHDLLWATLWEGQALVREGINRSNPKGSSWSIVEPPGSENGVMHISVGVSVVWAVTKDWKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGMNDQVWGIGCEDRAVYFRQGVTPSELSGKTWKAIIAARECDRSHSGSSSSLLSAGCFFGDEVRGSGESAPSDTDASSEVERPGPGQILPAEPLDDSKNATGNSASGLGAGRTAEDTVEDACPAEGSREARPNTHPGPAPTPAELPWTNIDLKEAKKVPSHSAAGFPETTSLSSLGLLPLGLEEPYGVDDHPLWAWVSGGGCVVEACAMPRWFTVQAGLSSSVHMLSLSITPAQTAAWRKQIFQQLTERTKRELENFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRLALEQFTGHDGVRDSILFIYYVVHEEKKYIHIFLNEVVALVPVLNETKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVQGRPSPQAIWSITCKGDIFVSEPSPDLEAHEHPLPCDQMFWRQMGGHLRMVEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKCVHIYENQRWNPVTGYTSRGLPTDRYMWSDASGLQECTKAGTKPPSLQWAWVSDWFVDFSVPGGTDQEGWQYASDFPASYHGSKTMKDFVRRRCWARKCKLVTSGPWLEVPPIALRDVSIIPESPGAEGSGHSIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASISIGACYQVWAVARDGSAFYRGSVYPSQPAGDCWYHIPSPPRQRLKQVSAGQTSVYALDENGNLWYRQGITPSYPQGSSWEHVSNNVCRVSVGPLDQVWVIANKVQGSHSLSRGTVCHRTGVQPHEPKGHGWDYGIGGGWDHISVRANATRAPRSSSQEQEPSAPPEAHGPVCC
Protein
Tectonin beta-propeller repeat-containing protein 1: TECPR1