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TCEAL7

Gene
TCEAL7
Protein
Transcription elongation factor A protein-like 7
Organism
Homo sapiens
Length
100 amino acids
Function
Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
Similarity
Belongs to the TFS-II family. TFA subfamily.
Mass
12.324 kDa
Sequence
MQKPCKENEGKPKCSVPKREEKRPYGEFERQQTEGNFRQRLLQSLEEFKEDIDYRHFKDEEMTREGDEMERCLEEIRGLRKKFRALHSNHRHSRDRPYPI
Protein
Transcription elongation factor A protein-like 7: TCEAL7

Gene
Tceal7
Protein
Transcription elongation factor A protein-like 7
Organism
Mus musculus
Length
98 amino acids
Function
Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines (By similarity).
Similarity
Belongs to the TFS-II family. TFA subfamily.
Mass
11.697 kDa
Sequence
MQKSCNEKEGKPKGSEAKREDEQPCGALEGQRLEGNFRQRLLQSLEEFKEDIDYRHFKGEEMTGEEEEMERCLEEIRSLRKKFRALHSNRTHSRDHPF
Protein
Transcription elongation factor A protein-like 7: Tceal7

Gene
Tceal7
Protein
Transcription elongation factor A protein-like 7
Organism
Rattus norvegicus
Length
98 amino acids
Function
Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines (By similarity).
Similarity
Belongs to the TFS-II family. TFA subfamily.
Mass
11.933 kDa
Sequence
MQRSCNEKEGKPKCSEPKREEEHPYGAFEGQRLEGNFRQRLLQSLEEFKEDIDYRHFKGEEMTGEEEEMERCLEEIRSLRKKFRALHSNRTHSRDRPF
Protein
Transcription elongation factor A protein-like 7: Tceal7