Protein
Acetyl-CoA acetyltransferase
Organism
Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Function
Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the beta-keto thiolysis of acetoacetyl-CoA, leading to 2 acetyl-CoA molecules.
Similarity
Belongs to the thiolase-like superfamily. Thiolase family.
Sequence
MTREVVLVGACRTPVGTFGGTLKDVGSAQLGAIVMGEAIKRAGIKAEQIDEVIFGCVLQAGLGQNVARQCMINAGIPKEVTAFTINKVCGSGLRAVSLAAQVIKAGDADIIMAGGTENMDKAPFILPNARWGYRMSMPKGDLIDEMVWGGLTDVFNGYHMGITAENINDMYGITREEQDAFGFRSQTLAAQAIESGRFKDEIVPVVIKGKKGDIVFDTDEHPRKSTPEAMAKLAPAFKKGGSVTAGNASGINDAAAAVIVMSKEKADELGIKPMAKVVSYASGGVDPSVMGLGPIPASRKALEKAGLTIDDIDLIEANEAFAAQSIAVARDLGWADKMEKVNVNGGAIAIGHPIGSSGARILVTLLYEMQKRGSKKGLATLCIGGGMGTALIVEAL