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Shroom2

Gene
shroom2
Protein
Protein Shroom2
Organism
Xenopus tropicalis
Length
1726 amino acids
Function
May be involved in endothelial cell morphology changes during cell spreading. Required for eye pigmentation. In the retinal pigment epithelium, regulates the biogenesis of melanosomes and promotes their association with the apical cell surface by inducing gamma-tubulin redistribution.
Similarity
Belongs to the shroom family.
Mass
195.259 kDa
Sequence
MLVLGCLQCFTSAWGFASRRICHSSSATPGQHSVGLGHGYQHGAQSWAERFLLRYKGLLWFVGSRAHSGGEETNGKLQAGGCYSYWRGSLGIYFERGKEHGEPLIITKVEDGNKAADILMAGDEIVNINDQQLLGYRQEAICLVKGSHKILKMIVKRRNDISYRPHSWHSNKLIESAMDTVTPQMSNASPFWNARYRSSSSSHDLSNPWDQTSLQRNSGHFSSMGSMDSIDQTYQFGRLSSAKSNNSIDYVGSQNKRDSAYGSFSASFSTPDHTLSKTASASTENILYKNNEWDNTKLGYGKTSPSMNEVRRSADRQVLQSTSINETSKIQRTEDNTEPRYSGRSNFGPVWNIPDKKKTASPPPPPPPQRSDSYAVTKIHEKPTNLMHLDASSTQHFNVANRSQAKPDWSLEISEQQRPIRAHDRTVADTRRTSNSSYHAGLNADQGLSPYKDKYPSNLPNVSRIQASLSTNDVRFAQPAYNYHHQRQYSDESTLFQSTRTSAQHKSQQQPMKYESSVNQVPSDLTYVYHPHQFRAPATSAGFSSGKQNVENNGQNHFHVVSIKHPQGNTTHHQFKEEENYAPEVNSGRKSVQPENTVISIEIPAYSLPQESFEPSQINCEKNYLKISEKKDNYLGNNEQIINKTTGYSEEKCNDRFSQLDHSEKGSYRSSQDYSWRKEENKITPLVTPMLHSLAQEGRNRSESFPDTGNEKLSFPDAGKQSRRSDRFATTLRNEIQQRRARLQKSKSTAALTESNETETSDNWKQDSLESMSPTSEGSFSSTYRSHLQEAQARVLRATSFKRRDLDTGISDHLSLFQDRNMQISSFSGLSLDPVQPKKNTAVNSSQNVSRIGARKRFTTQQKLMSYSEPEKINEVGVEDQYNFRTENSTKRTVGSFADRWKFFEETSKCAQPKVPPKVVSSSQSEETSEIAINRDYAKSSEGQESKRALAVSGQNPADENGFPDKVTTERRQRLGTFAEYEASWKEQKTQLERKNSGRCHSADNILDADLEQNPKAQYIHERSKSSPTTDFYAQAAAVESKQQSESVRRDTENSNSTHCRSSTGDSPTRTVEAGDQCGATNEQEVLTCNTKWKPHDKSFPIPETSNESQQSRARSGTLPNDYRFAHENVNQGNRDISFSAVPISEACPDFSNADSDQLQDHPSVFKKRSAAPQRPPPPKLENKYWRQNGSSSSLATSSESLLTAQARRAQSYSPSSQDTFPPQSLQKQSPSTYPDKNPSIHIYDYQLSVPPENDRYHLEKKYFESELSSKSHLQIPGMEPSRSPSPQFAPQKLTDKPPLLVPEENLSRIERVIDNTTVKMVPIKIVHSETHAEKESRHNLLSAIEPTALPTGLAKDQLKTLSTSEQSYSRFCAYTRQESREEEESRVTDLYSCQRNAEDDNENDVSSLAPSNAKSKDAIYADLKSEELVREIVDKDKSLADILDPNAKMRTTMDLMEGIFPKDEHLLEEAQQRRKHLPKIPSPRSTDDKKDEQNVPSAVSLTTSSTYYSTSAAKAELLIKMKDMQEQQHIAENSEDELGQNLSEKKQELIDSISKKLQVLRDAKETLLEDVQCNNALGEEVEIIVKEVCKPNEFDKFRMFIGDLEKIVNLLLSLSGRLARVENALNNLDETVSPEERKTLLEKRKLLTRQHEDAKELKENLDRRERTVYEILANYLNEENLADYEHFVKMKSALILEQRELEDKIKLRESQLKCLTDSLPLDRIK
Protein
Protein Shroom2: shroom2

Gene
SHROOM2
Protein
Protein Shroom2
Organism
Homo sapiens
Length
1616 amino acids
Function
May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity).
Similarity
Belongs to the shroom family.
Mass
176.41 kDa
Sequence
MEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVGLWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAGEAEDGTGRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSEDTVGTFADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEERKEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKELKENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLLDSLQPERGK
Protein
Protein Shroom2: SHROOM2

Gene
Shroom2
Protein
Protein Shroom2
Organism
Mus musculus
Length
1481 amino acids
Function
May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution.
Similarity
Belongs to the shroom family.
Mass
164.703 kDa
Sequence
MEGAEPRARPERLAEAEAPATDGVRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVAINDVSLSGFRQEAICLVKGSHKTLKLVVKRKSDPSWRPHSWHATKYFDVHPEPAASLFLNTSGSPSWKSQHQASSSSHDLSGSWEHTSLQRTSDHFSSMGSIDSLDHSSQLYPSGHLSSAKSNSSIDHLGGHSKRDSAYGSFSTCSSTPDHTLPKADASSTENILYKVGLWEASRPGSSRQSQSTGDPQGLQDRPSCFIPRVPGNSSKSPRPEDNVEPKIATHGRSNFGPVWYVPDKKKAPSPPPLGLPLRSDSFSVAARGHEKARGPPFSDLASMQHFITLPHVQPRGDHRMETTDRQWKLTHLSSGKEIGNVGYQSEGHLDCRWLCSDDRAGRPSGPPGRLQFSDVHFLKSYHGSQHQQQCSDESPRAPSSPRELLHITPGGGLQEPPEPSQDDNPTQVRWPGSAHQKLDDRGRSHYFPGSLRQPVQGSAQVVIPRGDYWHSDTTPVDLEYPLLRPVGQRTYLQQHEETPASHEKEGYHQLNAGIEGCCSGIQEPPRASRTVRTGLQCPSNDFKLVDGESGRISRQRTPMLHSLTQDGTWRPGNSKDCGNDKPPLFDAQVGKPTRRSDRFATTLRNEIQMRRAKLQKSKSTVTLAGDSEAEDCAGDWRADVGAVPEGSFPSTYKEHLKEAQTRVLKATSFQRRDLDPTPADQYSGPSEHRTFDHSASSSLSSFPGEPDSAPRFCETGLAKAPSSGVGVPHVLRIGGRKRFTAEQKLKSYSEPEKINEVGLSGDHRPHPTVRTPEDTVGTFADRWKFFEETSKSLLQKAGHRQVHCGLPREKAERPQTGHHECESTEPWFQKRSLATSCGEILSDRKVEKASEKLNPPRRLGTFAEYQASWKEQKKPLEARSSGRYHSADDILDAGLDQQQRPQYIHERSRSSPSTDHYSQEVPVEPNRQAEDSGDHKEAILCTLQAEEGCSAPSAQPQDSQHVNEDTTFPQPETQLSSKCQHLQTSAMETSRSPSPQFAPQKLTDKPPLLIHEDNSARIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAELPPLPSGLERDQIKTLSTSEQCYSRFCVYTRQEVEAPHRARPPEPRPPSTPAPPVRDSCSSPPSLNYGKAKEKTMDDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEYLLEEAQQRRKLLPKVPLPRVTEDKKQDPGMPGVVSLATNSTYYSTSAPKAELLIKMKDLQEPEEYSAGDLDHDLSVKKQELIDSISRKLQVLREARESLLEDIQANNALGDEVEAIVKDVCKPNEFDKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDNPSPGDRQSLLEKQRVLTQQHEDAKELKENLDRRERIVFDILATYLSEENLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLFDSLQPERSK
Protein
Protein Shroom2: Shroom2

Gene
Shroom2
Protein
Protein Shroom2
Organism
Rattus norvegicus
Length
1423 amino acids
Function
May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity).
Similarity
Belongs to the shroom family.
Mass
157.989 kDa
Sequence
MRPSTVTSRIWWSESSSSSSHDLSGSWEHTSLQRTSDHFSSMGSIDSLDHSSQLYPSGHLSSAKSNSSIDHLGGHSKRDSAYGSFSTCSSTPDHTLPKADASSTENILYKVGLWEASRPGSSRQSQSTGDPQGLQDRPSSFLPRVPGNSSKSPRPEDNIEPKIATSGRSNFGPVWYVPDKKKAPSPPPLGLPLRSDSFAVAARGHEKARGPPFSDLASMQHFTTLPHVQPRGDRRMETTDRQWKLAHPSSGKEIGNVGYQPEGHLDCRWLCSDDRAGRPSGAPGRHQFSLSSTDVHFLKSYHGSQHPQPCSDESPRFPSSPRELLRITPSGCLQEPPELSQDDNPAQVRWPGSVNQKLDDRGRSHYFSVPHRQPVHGSAHVLIPRSDYWHSDTTPVDLECPLLRPDQRGYPQQYEETPASHERGGYQQLNAGIEGCCSGIHEPPRASHTVRAGLQCPGNDFKLVDAESGRISRQRTPMLHSLTQDGAWRPGNSKDCGNEKPPLLDAQVGKPTRRSDRFATTLRNEIQMRRAKLQKSKSTVTLAGDSEAEDCAGDWRVDVGAVPEGSFPSTYKEHLKEAQTRVLKATSFQRRDLDPTPADQYPGPPEHRTCDHSASSSLSSFPGEPDSAPRLCEAGLAKPPSSAGGVPHILRIGGRKRFTAEQKLKSYSEPEKINEVGLSGDHSPHPTIRTSEDSVGTFADRWKFFEETSKSLLQKPGHRQAFCGIPREKAERPQTQGHECESTEPWFQKRSRATSCGEILSEDRKVEKASEKLNPPRRLGTFAEYQASWKEQKKSLEARSSGRYHSADDILDAGLDQQQRPQYIHERSRSSPSTDHYSQEVPVEPNRQAEDSGGQKEALLCTLQAEEGCSAPSSSVLSSAQPQDSQHVNEDPTSPQPEAQLSSKCQHLQTSTMETSRSPSPQFAPQKLTDKPPLLIHEDNSARYCPVTACYVFIPCRLQVFVAGALPQLQTLGIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAELPALPSGLEKDQIKTLSTSEQCYSRFCVYTRQEVETPHRARPPEPQPPSTPAPPVRDSCSSPPSLNYGKAKEKTVDDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEYLLEEAQQRRKLLPKVPSPRVTEDNSCPSLSAICYNLGTRSKSVPVSQLIKIKILASSPRKQDPGMPGVVSLATNSTYYSTSAPKAELLIKMKDLQEPEEYSAGDLDHDLSIKKQELIDSISRKLQVLREARESLLEDIQANNALGDEVEAIVKDVCKPNEFDKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDSPSPGDRQSLLEKQRVLTQQHEDAKELKENLDRRERIVFDILATYLSEENLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLFDSLQPERSK
Protein
Protein Shroom2: Shroom2