Protein
WASH complex subunit 4
Organism
Drosophila melanogaster
Function
Acts at least in part as component of the WASH complex which may regulate wash nucleation-promoting factor (NPF) activity and is required for its membrane targeting during endosomal sorting (By similarity). During embryogenesis, not involved in the wash-dependent developmental migration of hemocytes anteriorly from the tail (PubMed:25739458).
Similarity
Belongs to the SWIP family.
Sequence
MFAEDILRDYGSFISEHDGKLKLLRDKVPNRDVSESAQCVYMSPVVEVNFMGNDSMAPDRSFEESELVANKPLTTLANLCNQCRNLSRKAKRFQLAFLFSDFRLDDTLPPHTHTSEGSAGLEGSLVRMSSSMDFFCQVYFLLNRMIVILQNLWRQIAASVSVPMDINEVHIFAVFDAMSELLEHIVVFNELANQSKISTMWALYKKWLMNLSNSQSANLELNGLSTSLMDIENLITKDFFRILLDNLMELKKQFGLNSVSPITQHSNAYIRRQLLDVDANPSNELKNYEDPKHIIRLTTFVVVVHELGIQMEGKLVKNVIDLVARHKQVPLNRSVFWSPSGFLSLHAKTLMKSSARSQDGQGPKVHSTVLEKFRLSDQRTCRQLGVQLSLWSIQMQRVFDVGVFGHLKTFLQLILNGHSYADQVNLLAVALINRHVALMTPMTRNDWIVVSRLLQYLKVIQKTFESNQINFVRFISSLIQWQKQKVIHLLHTTKKKIVVLKLLQRKINFLATIKLAEKSIMGFPSKQRLTFVNLALGEFLDNRLLPADNQKLIKSILHRVNSISDIMRNIGGQLNTSESSSLVYNHWFLDTSVLKEYTELQRNPYSLQNLVSVSHHLDKIMAMFRGSRCPKQSANDLIIEFLSNHLEFFLRVEALSHLFQSQDQPFQQSALDYRLCINAVAVENDGDYNIIKDHLENYFTATFYNLTTIAPHDWKSYEKMRHLANKVLQLQPIDDHLPNQIIDQGIDVLQIMRNIHTFASSYAYNMNLQVFVETNSRSKHLDIIGTRHVANSVQTHGTGIINTTVNFIYQFLRQKFYTFSTFLHDEQIKSRLLKELRFHTEHKHSKSYQSYPYERADSFLKKIRRLGCSSNGETYMDLFRKVITQVGNAVGYVRLLQAGSKNANFRNRSYKTRFDSNFSCGGSKVHEATEGSIREYEKSLGHMKECYSDSTNYFKLLLQGFQPFLCNPHNHHLRTFYLITPALIMNYIDYRVKQKLKIYKKDQTKISLFEDGFAIGLVYILNMLNQQTEFHELGWSQTITQHLNAERSKVRDILAGQQRTAPEQLDEKLHQTVAITERHVNAYEHEYNLLYATLSSSEIFFQ