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SUCLA2

Gene
SUCLA2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Macaca fascicularis
Length
463 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
49.96 kDa
Sequence
MAASVFYGRLLAVATLRNHRPRTALGAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMSMELLQEAGVSIPKGCVAKSPDEAYAVAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSQGGVNIEDVAAETPEAIITEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAQANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMSCDVIAQGIVTALKDLEIKIPVVVRLQGTRVDDAKALIAGSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI

Gene
Sucla2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Mus musculus
Length
463 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
50.114 kDa
Sequence
MAASMFYGRQLAAAALRSHRPQTTLRAAAQVLGNSGLFNKHGLQVQQQQQRTLSLHEYLSMELLQEAGVSVPKGFVAKSSDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFTSGLKGGVKIVFSPEEAKAVSSQMIGQKLITKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSAQGGVNIEDVAAENPEAIVKEPIDIVEGIKKEQAVTLAQKMGFPSNIVDSAAENMIKLYNLFLKYDATMVEINPMVEDSDGKVLCMDAKINFDSNSAYRQKKIFDLQDWSQEDERDKEAANADINYIGLDGSIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVQQVTEAFKLITSDKKVQAILVNIFGGIMRCDVIAQGIVMAVKDLEIRIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVVKLSEIVTLAKEAHVDVKFQLPI

Gene
SUCLA2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Bos taurus
Length
463 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
50.13 kDa
Sequence
MAASVFYSRLLAAATLRSHRPRTALPAAAQVLGSSGLFNNHGVQIQHQQQRNLSLHEYLSMELLQEAGVSIPKGHVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERRYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAETPEAIVKEPIDIVEGIKKEQAVRLAQKMGFPASIVDSAAENMIKLYDPFLKYDATMVEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKADLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLSILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPIVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVVKLSEIVTLAKQAQVDVKFQLPI

Gene
SUCLA2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Homo sapiens
Length
463 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:15877282). The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity).
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
50.317 kDa
Sequence
MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI

Gene
SUCLA2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Sus scrofa
Length
425 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
46.259 kDa
Fragment
single
Sequence
NNHGLQIQQQQQRNLSLHEYMSMELLQEAGVSIPKGHVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERRYPRREYYFAITMERSFQGPVLIGSSQGGVNIEDVAAETPEAIVKEPIDIVEGIKKEQAVRLAQKMGFPPSIVDSAAENMIKLYNLFLKYDATMVEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLSILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVVKLSEIVTLTKQAQVDVKFQLPI

Gene
SUCLA2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Columba livia
Length
413 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
44.975 kDa
Fragment
single
Sequence
RRLSLHEYLSMGLLQEAGISVPHGVVARTPDEAYKIAKEIGSKDLVIKAQVLAGGRGKGTFEGGLKGGVKIVFSPEEAKAVSSRMIGKKLFTKQTGEKGRICNQVFVCERRYPRREYYFAITMERSFQGPVLIGSSQGGVNIEDVAAENPDAIIKEPIDIVEGIKKEQAVRLAQKMGFPSNLVDEAAENMIKLYNLFLKYDATMIEINPMVEDASGVVMCMDAKINFDSNSAYRQKKIFDMQDWTQEDERDRQAAKADLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVVAVKDLDLKIPVVVRLQGTRVDDAKALITASGLKILACDDLDEAAKMVVKLSEIVTLAKQAHLDVKFQLPI

Gene
Sucla2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Mesocricetus auratus
Length
221 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
24.249 kDa
Fragment
multiple
Sequence
DVVIKAQVLAGGRIVFSPEEAKLITKQTGAKGRICNQVLVCERREYYFAITMERSFQGPVLIGSAQGGVNIEDVAAENPEAIVKKMGFPSNIVDSAAENMIKLYNLFLKINFDSNSAYRQKIFDLQDWSQEDERLHGGTPANFLDVGGGATVQQVTEAFKVQAILVNIFGGIMRLQGTRVDDAKILACDDLDEAAKMVVKLSEIVTLAKEAHVDVKFQLPI

Gene
SUCLA2
Protein
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Organism
Canis lupus familiaris
Length
20 amino acids
Function
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Similarity
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
Mass
2.248 kDa
Fragment
single
Sequence
LSLHEYMSMELLQEAGVSIP