Protein
Septin and tuftelin-interacting protein 1 homolog 1
Organism
Arabidopsis thaliana
Function
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events (By similarity). Involved in snRNPs recycling (PubMed:25568310). Required for efficient splicing of genes that act within the plant circadian clock (PubMed:23110899). Part of a transcription elongation checkpoint at alternative exons (PubMed:25568310). Required for correct expression and splicing of DOG1, a regulator of seed dormancy (PubMed:25568310). May induce transient transcriptional pausing of polymerase II at slices sites (PubMed:25568310).
Similarity
Belongs to the TFP11/STIP family.
Sequence
MDEYQDMERFSMDNDYEGGRWEGDEFVYQKRKEKRKQTKNDATYGIFAESDSDSDDSGGGGSRRKRRKDRDSGRKADLTKPVNFVSTGTVMPNQEIDKDSREHNDEKDRDKIEDNDMIDEDVEVRGGLGIGSSGLGLGFNANGFDDEDNLLPGALGKKIADRAKMRGKAKVEKRGQEGGGAKGGKKNTLGSDIGQFEKSTKGIGMKLLEKMGYKGGGLGKNQQGIVAPIEAQLRPKNMGMGYNDFKEAKLPDLKKVEEKKIIGVSVSENEQSHGDRGGKNLWKKKKVRKAVYVTAEELLEKKQEAGFGGGQTIIDMRGPQVRVVTNLENLDAEEKAKEADVPMPELQHNLRLIVDLVEHEIQKIDRDLRNERESALSLQQEKEMLINEEEKQKRHLENMEYIADEISRIELENTSGNLTLDSLAIRFEDLQTSYPDDYKLCSLSTIACSLALPLFIRMFQGWDPLSDAVHGLKAISSWRKLLEVEEDHNIWVVSTPYSQLVSEVVLPAVRIAGINTWEPRDPEPMLRFLETWETLLPSSVLQTILDTVVLPKLSTAVEYWDPRRELVAIHVWVHPWLPILGQKLEFLYQIIQMKLSNVLDAWHPSDSSAYTILSPWKTVFDTTSWEQLMRRYIVPKLQLALQEFQVNPANQNLERFDWVMKWASAVPIHLMADMMERFFFPKWLDVLYHWLRAKPRFEEIQGWYYGWKELFPQELTANERIRIQLKRGLDMLMEAVEGVEVSQPRAKANERTQSVPAQAQAQAKAQMDSTEVLSLKEVLEVFAQEQELLFKPKPNRMHNGLQIYGFGNVSVIIDSVNQKLLAQKDGGWFLVTPDDLLRMHNNTTVSAKR