Protein
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
Organism
Xenopus tropicalis
Function
Involved in the production of gangliosides GD3 and GT3 from GM3. Gangliosides are a subfamily of complex glycosphingolipids that contain one or more residues of sialic acid; glycosphingolipids are required for convergence extension movements during early development (By similarity).
Similarity
Belongs to the glycosyltransferase 29 family.
Sequence
MKLQGSRMWLCPRTRLPVGASALGFLILCWLYVFPGYRLPGHKEMVREVLRFGPGWRKNRTEMDSFRKLLQDCCDPPHLFSLTKVNTPLGENLWFDGEFFHSLTIDNSTRSLFPQDTPFKLPLKRCSVVGNGGILKNSRCGEQIDEADFVMRCNLPPLSREYTEDVGTRTQLVTVNPSIIDKRYQNLLWSRKSFVENLRVYQQSYVYMPAFSTKRGTDPSLRVYYTLADFGTNQTVLFANPNFLRNVGKFWKSRGIHSKRLSTGLFMVSAALSLCEEVTIYGFWPFQMDLGGRYISHHYYDNTLPLSGVHAMPEEFLQLWLLHKSGVLQMQLDQCKKDVSSQKPH