Protein
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Function
Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
Similarity
Belongs to the HTP reductase family.
Sequence
MVMKPYVIIFSTVSIDGRLATKTGYSELSCPYDKQRQHEIRSEVDAVMVGANTVRVDNPSLTVKYGKNRRNPIRVVVTRSFNLDPSYKIFTTPPSTVIYTSNYESEKVEEFIRKGVIVRKFLHLDDLLEDLYDNFNVRRLMVEGGGHLIWWFIKDNLYDEIRITISPRIFGNGVSFTQGEGFIGEDSPRLELIDAKICECGNEVHLTYKKYMT