About Products Protein Database Contact

SSD1

Gene
SSD1
Protein
Virulence protein SSD1
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
1274 amino acids
Function
Plays a role in resistance to host antimicrobial peptides such as protamine, RP-1, or human beta-defensin-2; allowing colonization of human tissues. Required for resistance to membrane permeabilization and maintenance of mitochondrial membrane potential upon exposure to RP-1.
Similarity
Belongs to the RNR ribonuclease family.
Mass
141.28 kDa
Sequence
MSSSQDYNNNSNNTPARVSSRKGKNLHVAHRRSPSELTNLMVEQYNLQRQLEEVQAQQKLLEEKQKQQQQQFTYPSAQGSSELAPPPISSGYGGNRSSHSRSSSINTHRRTGSGSGGTAHGHSRRHSLGLNEAIKAAANQKQSNRNSLSPTIPNEAKTDSSDDIGSFKFPPSGGDQGDTSGQSSSSHNRSRSLAYGQQSFKFPPTPDQSNDTRGNSLLPPNPNFSVTQSPDRGHNRRSSHFRTGSRGSGSNTNTDGINSNWRAQQQSPQQQQRQGGLLEPPQVGFTPGHKPRNSSYGGGSSVSSLQQFLPNNGGSNNSGQQGGHQGGGNNGRKTLFAPYLPQSSLPELINEGRLVTGTLRVNKKNRSDAYVSTDGLLDADIFICGSKDRNRALEGDLVAVELLIVDEVWESKKEKEEKKRRKDNTLHSRPLTDDIHNDATSAPNTAEGSVTGTSKEDGAGSNEEETGGLARRGSLKQRPTMKKNDDVEVEGQSLLLVEEEEINDEIKPLYAGHVVAVVDRIPGQLFAGTLGLLRPAQAAQAARDKKNGKESTVQNPKAPKIVWFKPTDKKVPLIAIPTEQAPKDFVENHEKYADRLFVASIKRWPITSLHPFGTLVSNLGPIDSPETEIDSILRDNNFLCDEYPDDDNDDIVSVNAYDLPSIEPEFENTQREEYLNDYIIAFTQNGEFVDHALHVKRISNTKIELGFHVADIAYFIKPGSSLDRKSKKRSSSVFLPQKTVNLFPKQVNKIVSFKENEKNLAVSVVFEIDTSNFEVEDLYIHESVIVPKQLVTYDAFDTILSGQSVDSISSATSDYVKTFSLIAKEFRRHRLSNRSLGITPNLTLLDQLDDEKVRLDLNIFKDSLAFDVISEISHKVNSAIAAKVHAGLGDQAILRRHPLPTLQKMETFVRKATSLGFKIDTTTSSTLQNSILKIDDPVKRKCVETLLYKCMSRGRYYVAGKQDTDSYAHYYFNLPLYTHFTAPLRRYADLIVHRQLKAVLNKQVEDKDLDSLKAITDYCNFKKDCAANAQEQAIHLLLSQTINEMSETAGQLLCMGTVVQVYESSFDVFIPEFGVEKRVHGDQLPLVKAEFDKNERILELWWEKGVDSATYIPPDEKSSLSYRNSIKNKYRTSALQAAKIQSKTALEKSTTPADSVAEKLAKLNLEPPKLVVPSLKSNELHEVEKDETKSMPSSPTQSEIPKNVRTNSSSRISSSGNTFSLEPYLQNTITRIEGDSYIQVIKELTQVPVLLRAEIGMALPCLTVRVLNPFAEEQ

Gene
SSD1
Protein
Protein SSD1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
1250 amino acids
Function
Can suppress the lethality due to deletion of SIT4, and partially the defects due to BCY1 disruption. Is implicated in the control of the cell cycle G1 phase.
Similarity
Belongs to the RNR ribonuclease family.
Mass
139.954 kDa
Sequence
MSKNSNVNNNRSQEPNNMFVQTTGGGKNAPKQIHVAHRRSQSELTNLMIEQFTLQKQLEQVQAQQQQLMAQQQQLAQQTGQYLSGNSGSNNHFTPQPPHPHYNSNGNSPGMSAGGSRSRTHSRNNSGYYHNSYDNNNNSNNPGSNSHRKTSSQSSIYGHSRRHSLGLNEAKKAAAEEQAKRISGGEAGVTVKIDSVQADSGSNSTTEQSDFKFPPPPNAHQGHRRATSNLSPPSFKFPPNSHGDNDDEFIATSSTHRRSKTRNNEYSPGINSNWRNQSQQPQQQLSPFRHRGSNSRDYNSFNTLEPPAIFQQGHKHRASNSSVHSFSSQGNNNGGGRKSLFAPYLPQANIPELIQEGRLVAGILRVNKKNRSDAWVSTDGALDADIYICGSKDRNRALEGDLVAVELLVVDDVWESKKEKEEKKRRKDASMQHDLIPLNSSDDYHNDASVTAATSNNFLSSPSSSDSLSKDDLSVRRKRSSTINNDSDSLSSPTKSGVRRRSSLKQRPTQKKNDDVEVEGQSLLLVEEEEINDKYKPLYAGHVVAVLDRIPGQLFSGTLGLLRPSQQANSDNNKPPQSPKIAWFKPTDKKVPLIAIPTELAPKDFVENADKYSEKLFVASIKRWPITSLHPFGILVSELGDIHDPDTEIDSILRDNNFLSNEYLDQKNPQKEKPSFQPLPLTAESLEYRRNFTDTNEYNIFAISELGWVSEFALHVRNNGNGTLELGCHVVDVTSHIEEGSSVDRRARKRSSAVFMPQKLVNLLPQSFNDELSLAPGKESATLSVVYTLDSSTLRIKSTWVGESTISPSNILSLEQLDEKLSTGSPTSYLSTVQEIARSFYARRINDPEATLLPTLSLLESLDDEKVKVDLNILDRTLGFVVINEIKRKVNSTVAEKIYTKLGDLALLRRQMQPIATKMASFRKKIQNFGYNFDTNTADELIKGVLKIKDDDVRVGIEILLFKTMPRARYFIAGKVDPDQYGHYALNLPIYTHFTAPMRRYADHVVHRQLKAVIHDTPYTEDMEALKITSEYCNFKKDCAYQAQEQAIHLLLCKTINDMGNTTGQLLTMATVLQVYESSFDVFIPEFGIEKRVHGDQLPLIKAEFDGTNRVLELHWQPGVDSATFIPADEKNPKSYRNSIKNKFRSTAAEIANIELDKEAESEPLISDPLSKELSDLHLTVPNLRLPSASDNKQNALEKFISTTETRIENDNYIQEIHELQKIPILLRAEVGMALPCLTVRALNPFMKRV