SSC1

Heat shock protein SSC1, mitochondrial

655 amino acids

Acts as a non-catalytic component of endonuclease SceI (endo.SceI), which cleaves specifically at multiple sites on mitochondrial DNA and produces double-stranded breaks. SSC1 confers broader sequence specificity, greater stability, and higher activity on the catalytic subunit.

Belongs to the heat shock protein 70 family.

70.8 kDa

MLAAKNILNRSSLSSSFRIATRLQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARGQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNNGNNAESDETKQ

SSC1

Heat shock protein SSC1, mitochondrial

654 amino acids

Acts as a non-catalytic component of endonuclease SceI (Endo.SceI), which cleaves specifically at multiple sites on mitochondrial DNA and produces double-stranded breaks. SSC1 confers broader sequence specificity, greater stability, and higher activity on the catalytic subunit (By similarity).

Belongs to the heat shock protein 70 family.

70.628 kDa

MLAAKNILNRSSLSSSFRIATRLQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARGQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNNAESGETKQ

SSC1

Heat shock protein SSC1, mitochondrial

648 amino acids

Required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Constitutes the ATP-driven core of the motor and binds the precursor preprotein (By similarity).

Belongs to the heat shock protein 70 family.

69.748 kDa

MLSARNSLKNISRQFPKALTRAQSTAAAPTGPVIGIDLGTTNSAVAVMEGKTPKILENSEGGRTTPSIVAFTKDGERLVGIPAKRQAVVNPSDTLFATKRLIGRRYEDPEVQRDINQVPYKIVKHGNGDAWLEARGEQYSPQQIGGFILNKMKETAEAALSKKVNSAVVTCPAYFNDAQRQATKDAGKIVGLNVLRVINEPTAAALAYGLEKKDGEVVAVFDLGGGTFDVSILDIGAGVFEVKSTNGDTHLGGEDFDIALVRYIVDAFKKESGIDLEKDKMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINQKISRAQFEQLVEPLIKKTIEPCKKALKDAGLSTSDVSEVILVGGMSRMPKVVETVKSIFGKEPSKGINPDEAVAMGAAIQGGILAGEVKDVVLLDVTPLSLGIETMGGVFARLISRNTTIPAKKSQIFSTAAAGQTSVEIRVFQGERELTRDNKLIGNFTLSGIPPAPKGVPQIEVTFDIDTDGIIKVSARDKATNKDASITVAGSSGLSDAEIEKMVNDAEKFAESDKARREAIEFANRADQLCNDTENSLNEHKEKLSSESVQKVQDQIQQLREIVLKAQAGEEVSPEELKQKTEELQNEAINLFKDLYKDGGESSGSSEQPKN