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SRD5A1

Gene
SRD5A1
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Organism
Macaca fascicularis
Length
263 amino acids
Function
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
30.018 kDa
Sequence
MATAVAEELLLAEERMLAALAYLQCAVGCAVLARNRETNLAYGRHASPSFRVRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTFNGYLQSRYLSHWAVYADDWVTDPRFLIGFGLWLAGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHRWYLQKFEEYPKFRKILIPFLF
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1: SRD5A1

Gene
SRD5A1
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Organism
Homo sapiens
Length
259 amino acids
Function
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
29.459 kDa
Sequence
MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1: SRD5A1

Gene
Srd5a1
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Organism
Rattus norvegicus
Length
259 amino acids
Function
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
29.78 kDa
Sequence
MVPLMELDELCLLDMLVYLEGFMAFVSIVGLRSVGSPYGRYSPQWPGIRVPARPAWFIQELPSMAWPLYEYIRPAAARLGNLPNRVLLAMFLIHYVQRTLVFPVLIRGGKPTLLVTFVLAFLFCTFNGYVQSRYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKIPRGGLFEYVSAANYFGELVEWCGFALASWSLQGVVFALFTLSTLLTRAKQHHQWYHEKFEDYPKSRKILIPFVL
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1: Srd5a1

Gene
SRD5A1
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Organism
Bos taurus
Length
257 amino acids
Function
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology (By similarity).
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
29.186 kDa
Sequence
MELAERFLLDALAYLECALGVVCYVLLKLVGSPYGRYASSGSAFGLPARAAWTVQELPSLALPLLACAGAGAPAERLNRWPNCILLAMFLVHYAQRSLVFPFLIRGGKPMPLYAFLLAFIFCTYNGYLQSRYLSQYAVYADDWLSDPRFLTGSALWLIGMLINIHSDHVLRNLRKPGETGYKIPRGGLFEYISAANYFGEVVEWCGYALASWSIQGWAFAVFTFCVLFTRAQQHHKWYHEKFEDYPKFRKIMIPFLV
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1: SRD5A1

Gene
Srd5a1
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Organism
Mus musculus
Length
255 amino acids
Function
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology (By similarity).
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
29.344 kDa
Sequence
MELDELCLLDALVYLEGFLAFVAFVGLQMVGSSYGRYSSQWSGRRVPARPAWFLQELPSMAWPLYECIRPAAARLGNLPNRVLLAMFLIHYVQRTLVFPVLIRGGKPTLLFTFVLAFLFCTLNGYLQSRYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKIPRGGLFEYVSSANYFGELVEWCGFALASWSLQGVVFALFTLCALFTRARQHHQWYLEKFEDYPKTRKILIPFLL
Protein
3-oxo-5-alpha-steroid 4-dehydrogenase 1: Srd5a1