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SPRR1B

Gene
Sprr1b
Protein
Cornifin-B
Organism
Mus musculus
Length
153 amino acids
Function
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Similarity
Belongs to the cornifin (SPRR) family.
Mass
16.636 kDa
Sequence
MSSHQQKQPCTAPPQLHEQQVKQPCQPPPPEPCVSQVKTPCDTKVPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKVPEPCLPKAPEPCQPIVPEPCPSTVTPILAQQKTKQK

Gene
SPRR1B
Protein
Cornifin-B
Organism
Homo sapiens
Length
89 amino acids
Function
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Similarity
Belongs to the cornifin (SPRR) family.
Mass
9.888 kDa
Sequence
MSSQQQKQPCTPPPQLQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCHPKVPEPCQPKVPEPCHPKVPEPCPSIVTPAPAQQKTKQK