SPICE1

Gene

Spice1

Protein

Spindle and centriole-associated protein 1

Organism

Rattus norvegicus

Length

868 amino acids

Function

Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.

Mass

96.322 kDa

Sequence

MSLIRVNRFGPRGGARKTLKVKKKAAVRQEWDNTVNDLTVHRATPEDLVRRHEMHKSKNRALVHWELQEKALKRKWKKQKPETSSIEKRKLSIMKEILSDQYQTQDVLEKSDHLLTAAKGLFVDVPRKRTGFPNVTMAPGSSRSPAGINQDPGTQSILNESIIEPQALNEVDDGGAESTAHSQSEDSESELPNSLSPHSNRNTERFLHQLKEENSELINQLWTDIQQKIAAQSQRTPPGSPSSELSAEDQKGALNATDAVKRIQAGLQPEESAEPVDSSYVGQVLNTRKPKPLLSKVKRKQDMRALSKQKKNMLSSSTTSADLASSNNSSLDVLKHMIHEVEHEMEEYERWTGREVKGLQGGQGLTGFTLSLVSSLCRLVRYLKESETQLRKEVETRQQLEQMLGDHRELIDALTAEILLLREENGAVQARLQQYMVTTDEQLISLTHAIKSCPVINNSRQESQAPERAAMGRRLVDNVGAPVVNSNVSMPLMLKGEEMVDFPQEELPVKLSQGPPPTENLNLASNFPTHIFEPAVMLTPPRQKSNSEFSPLQDVLRRTVQTRPAPRIPPTVEVIEKEQTWEKKNLPIDPDIQNSSEESRLFTQRWRVSHMGDDLENKSQPQFVSLSQPPQFVSLSQPPCSSPPSTQQSRNPVFSEEPTVLGDGQQLGTADALMHRKDIMARIAELTLQNSAMKAHLNNITSSGGEHGDGLREPSRQGNASEVPANFPAVQSLMPSSMEERIAELNRQSMEARSKLLQLIEQQKLVGLTLSSSPVSPVESPLRAWTEEGKRTIEVSVPGVEASESSKCNTVSPVSGVSSRRSSGAISNSCSPLNATSGSGKFTPVNPRTKQTEKQSEEGWFALSAHLP

Protein

Spindle and centriole-associated protein 1: Spice1

Gene

SPICE1

Protein

Spindle and centriole-associated protein 1

Organism

Bos taurus

Length

860 amino acids

Function

Regulator required for centriole duplication. for proper bipolar spindle formation and chromosome congression in mitosis (By similarity).

Mass

95.713 kDa

Sequence

MSFVRVNRYGPRGGGRKTLKVKKKTSVKQEWDNTVTDLTVHRATPEDLIRRHEIHKSKNRALVHWELQEKALKRRWKKQKPEISNLEKRRLSIMKEILSDQYQLQDVLEKSDHLMATAKGLFVDFPRRRTGFPNVTMAPESSQSPTVVSKDPVTQAIRSESVIEPQALNEVDDDEQEGTVNSQSEESENELDNSLSSQSNANAGTFLHQIKEENSELINKLWTDIQQKVATQSQMTASSGTPSSASPSGEQKAALNATNAVKRIHTRLQPEESTETLDSSYVVGQVLNSRKQKQLLNKVKRKPDSRAPSKQKSSMLSASTASTDLPSSSNPSLDVLKHMIHEVEHEIEEYERWTGREVQGLQNSQGLTGFTLSLVSSLCRLVRYLKESELQLRKEVETRQRLEEALGDHRELIDALTAEVLFLREENTATQARLQQYMITTDEQLISLTHAIKNCPVISNKESQALERGATSQRHIDNPEDPAVNASVSMPLMFRGEDVVEFPQEDLPVKLSQVPNPPESGDLASSLPGHIFEPAVLLTPPRQKSNSEFSPLQDVLRRTVQTRPAPRIPPTVEIIEKEQNWEKKTLPVGADIQNSSDESHLFTQRWRASHMGEDSQSKTQAPFVSLSQPLCSSQSSMQQSRNPTLSEEPLVLGDGQQLRTNETLIQRKDIMARIAELTLQNSDIRAHLNNIIGPGGEQGDGLREFNRQETSHASDTMATFPAVQPLTPSSMEERIAELNRQSMEARGKLLQLIEQQKLLGLNPSSPPVSPVQSPLRAWAEGGKRTIEVSIPGAEAPESSKCSTDSPTSGLNSRRSSGAASNSCSPLNATSGSGRLTPLNPRAKIEKQNEEGWFALSTHVS

Protein

Spindle and centriole-associated protein 1: SPICE1

Gene

Spice1

Protein

Spindle and centriole-associated protein 1

Organism

Mus musculus

Length

860 amino acids

Function

Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.

Mass

95.645 kDa

Sequence

MSLIRVNRFGPRGGGRKTLKVKKKAAVRQEWDNTVNDLTVHRATPEDLVRRHEMHKSKNRALVHWELQEKALKRKWKKQKPETSSLEKRKLSIMKEILSDQYLTQDVLEKSDHLMAAAKGLFADVPRKRTGFPNVTRAPDSSQSHTGINQDPVTQSILNESIIEPQALNEVDDAGEQSTAHSQSEDSENELPNSLSQHSNRSTERFLHQLKEENSELINQLWTDIQQKIATQSQRTPPGSPSSELSAEDQKAALNATDAVKRIQAGPQPEEAAEPVDFSSSYLGQVLNTRKQKPLLAKVKRKQDMHAASKQKTNMLSSSTASADRPSSTGSSLDVLKHVIHEVEHEMEEYERCTGREVTGLQGGQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQMLGDHRELIDALTAEILSLREENSTMQARLQQYMVTTDEQLISLTHAIKNCPVINNSRQESQAPERAAMGRRLVDNVEGPVISSNGSMPLMFRGEEVVEFPQEELPVKLSQGPTPTENLNLANNFPTHIFEPAVMLTPPRQKSNSEFSPLQDVLRRTVQTRPAPRIPPTVEVIEKEQNWEKKALPIDPDIQNSSEENRLFTQRWRVSHMGEDLENKGQPAFVSLSQPPCSSLPSTQQPRNPVLSEEPTVLGDGQQLRTSEALVQRKDIMARIAELTLQNSAIKAHLNNITSSGGEQGDGLREPRKQGSASEVSTNFPAVQSLTPSSMEERIAELNRQSMEARSKLLQLIEQQKLVGLNLSSSPVSPVESPLRAWAEEGKRTIEVSVPGMEASESSKCNTVSPVSGNSSRRSSGAISNSCSPLNATSGSGKFTPVNPRTKTEKKNEEGWFALSAHIP

Protein

Spindle and centriole-associated protein 1: Spice1

Gene

SPICE1

Protein

Spindle and centriole-associated protein 1

Organism

Homo sapiens

Length

855 amino acids

Function

Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.

Mass

96.264 kDa

Sequence

MSFVRVNRCGPRVGVRKTPKVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNVTVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVNSQSGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGRRVMDSPERPVVNANVSVPLMFREEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLLTPPRQKSNLKFSPLQDVLRRTVQTRPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSEENRLFTQRWRVSHMGEDLENKTQAPFVNLSQPLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNESLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTSTFPVAQSLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEGAKRTIEVSIPGAEAPESSKCSTVSPVSGINTRRSSGATGNSCSPLNATSGSGRFTPLNPRAKIEKQNEEGWFALSTHVS

Protein

Spindle and centriole-associated protein 1: SPICE1

Gene

SPICE1

Protein

Spindle and centriole-associated protein 1

Organism

Pongo abelii

Length

855 amino acids

Function

Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.

Mass

96.235 kDa

Sequence

MSFVRVNRCGPRVGVRKTPKVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNITVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVTSQSGESENENELDNSLNSQSNTNTDRFLQQLTEENSELISKLWTDIQQKIVTQSQITPPGTPSSALSSGEQRAALNATNAVNRFQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNMLSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILRLREENAATQARLRQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGTRVMDSPEGPVVNANVSVPLMFREEVAEFPQEQLPVKLSQVPDPPDKMNLAKNFPAHIFEPAVLLTPPRQKSNLKFSPLQDVLRRTVQTRPAPRLLPTVEIIEKEQNWEEKTLPIDTDSQNSSEENRLFTQRWRVSHMGEDLENKTQAPFVNLSQPLCSSHSNTQQSRSPTFSEELPVLGDGQQLRTNESLIQRKDIMTRIADLTLQNSAIKAHMNNIIDPRGEQGDGLRELNKQESASDMTSTFPVAQSLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEGAKRTIEVSIPGAEAPESSKCSTVSPVSEINTRRSSGATSNSCSPLNATSGSGRFTPLNPRAKIEKQNEEGWFALSTHVS

Protein

Spindle and centriole-associated protein 1: SPICE1

Gene

spice1

Protein

Spindle and centriole-associated protein 1

Organism

Xenopus laevis

Length

793 amino acids

Function

Regulator required for centriole duplication.

Mass

87.704 kDa

Sequence

MSYLRASRTSSNLSLAKKPSKTRKKLQARKEWDSSVNDLTVFRATNEELEHRREIHRSKNQWLARWELQNKANYKQSEKENSTQFENSRLALMKEILSDQYLMNDVLERSDRALAVVKDLFGDAPRRHTGFPNVTMAPSCDLETSRAPIVRKKDPPTQLSILSESVMDSQAINEVDKSLSRSEYSDSEAEVSISIQPNMKAERVQQLLTGEGPKSEAFITPHKSEGDPSQTQCALNATTAVNRVKVRRTEEESPKPEESDSIIGRVLNPHGKANKRISLKGKKKRTTNQSQTKDFSTFKASERDLTTSNQSSLGLLNSMIMEVEQDLAEYERQTGREVLSAPPAHGLTGFTLSLVSSLKRVVSYLKESDLLLQREVRERQNLQGELVEQRLMLDALTAEILSLKEGGNIHENHSQTKQCPEVDGDKLTSITQEAKTFPGLNGETCRTSADCGLSKVNQFMDSQDVQDTDEKHSRLGVSKDEFGARLYPQGRPAEEPRLASALPSHVFQQAVLLSPPRQKTVGNLSSHSAVPKRAANRLPSPPADLMTAPVEIEWPESKLFQRSINYKNTAALIERGTMVPGQENSKHVYSSAQGSERVNQHPTESTKEVQGLEIGESQINPLQNEDLVSQMQQLALQNAALKAQLEQIHFSPEGNAPEEAAAEQLHNPEPATDTPARAALVPVSLEMRIAELNRQSAEARNKLLKLIEQQKQSIVVSPTLSPITPQGRRTGSSLDTTPLSSCSTSGRRSSGASNKSESISTSVGSLRSASTGRRSQAANDRGEGWFALSAHIS

Protein

Spindle and centriole-associated protein 1: spice1