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SP8

Gene
sp8
Protein
Transcription factor Sp8
Organism
Xenopus laevis
Length
500 amino acids
Function
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
Similarity
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Mass
49.231 kDa
Sequence
MLAATCNKIGSPSPSPSSLSDTSGSFGKGFHPWKRSSSTSSSCTLASGSLSGFSVGGSSRSANGSSSSSAAAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSGGSGGSGGGGSSGSMSAASPFANEYSVFPVSGGSQEAAAAAAAAAAAAAAAASHHQPVFLSKVHASVDGLQSIYPRVGMAHPYESWFKPSHPGEVSAAAAGGASSWWEVGAGWIDVQSPGAGAALHPGALQGSLHSPLGGYGTDYSAAGLGHFSTGGGGGVGSGGGAAGTGSGGGGGGSHLLSPGGQHLMDGFKPVIGPGSYPDPSSSPLSAGSMLAPTGPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSVGGGSTGSTGPGSGSKKGSDTDSEHSPSTSPTCHSPDLLHPPDRNGLE
Protein
Transcription factor Sp8: sp8

Gene
SP8
Protein
Transcription factor Sp8
Organism
Homo sapiens
Length
490 amino acids
Function
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
Similarity
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Mass
48.674 kDa
Sequence
MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
Protein
Transcription factor Sp8: SP8

Gene
Sp8
Protein
Transcription factor Sp8
Organism
Mus musculus
Length
486 amino acids
Function
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.
Similarity
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Mass
48.417 kDa
Sequence
MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSGSCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSGAHSQDSSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAADVGSAGASSWWDVGAGWIDVQNPNGAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGSSMLSAGPAAQLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGSAGSGGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
Protein
Transcription factor Sp8: Sp8

Gene
SP8
Protein
Transcription factor Sp8
Organism
Gallus gallus
Length
480 amino acids
Function
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.
Similarity
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Mass
47.402 kDa
Sequence
MLAATCNKIGSPSPSPSALSDSASSFGKGFHPWKRSSSSSSASAGSCGAVGSGLPGFGVAGAARNGSSAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSGAAAASSPFANDYSVFQAPGSAGGGGGGGGGGGGAAGQEAAHQPVFISKVHASVEGLQGIYPRVGMAHPYESWFKPSHPGLAAGEVGSAGASSWWDVGAGWIDVQSPNGAAALPGSLHPAAGGLQSSLHSPLGGYNSDYSGLGHSAFGGGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLGGGPAAPLSASPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGPGGAGGPGGGGPGPGPGGKKGSDTDSEHSAAGSPPCHSPELLPPPEPGHRNGLE
Protein
Transcription factor Sp8: SP8