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SNRPB

Gene
snrpb
Protein
Small nuclear ribonucleoprotein-associated protein B
Organism
Dictyostelium discoideum
Length
274 amino acids
Function
Core component of the small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs (By similarity).
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
28.157 kDa
Sequence
MSGMPKSSKMLQYINYRMRVTIQDGRVIVGRFLAFDKHMNVVICDAEEFRRIRQKGKEDREEKRTLGMILIRGETVVSMSVEAPPPEEAKLAATSKMPPQIPGGPGIGRAVGRGMPMGGMGMGGSGPMSGLTGPVRGVGGPAPHSMMPGGGVPPPMGRGGFPPQGFPPGGPSPQGAFNNNPNNNNGGPPQGFPPGGPIGRGGFPPQGFPPGGPMGGPNLNNGNMPPQGFPPGGPMGRGGFPPQGFPPGGPNFNNMPPQGFPPGGPMGRGGFQRK

Gene
SNRPB
Protein
Small nuclear ribonucleoprotein-associated protein B'
Organism
Bos taurus
Length
240 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
24.624 kDa
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRAGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP

Gene
SNRPB
Protein
Small nuclear ribonucleoprotein-associated protein B'
Organism
Gallus gallus
Length
240 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
24.588 kDa
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRVFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGAPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYTPGRGGPPPPMSRGAPPPGMMGPPPGMRPPMGPPMGMPPGRGAPMGMPPPGMRPPPPGMRGPPPPGMRPPRP

Gene
SNRPB
Protein
Small nuclear ribonucleoprotein-associated proteins B and B'
Organism
Homo sapiens
Length
240 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:12975319).
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
24.61 kDa
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP

Gene
SNRPB
Protein
Small nuclear ribonucleoprotein-associated protein B'
Organism
Macropus eugenii
Length
240 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
24.625 kDa
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLSGAAGGPGIGRAAGRGVPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQHPPGRGGPPPPMGRGRPPPGMMAPPPGMRPPMGPPTGMPPGRGAPMGIPPPGMRPPPPGMRGPPPPGMRPPRP

Gene
SNRPB
Protein
Small nuclear ribonucleoprotein-associated protein B'
Organism
Monodelphis domestica
Length
240 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
24.542 kDa
Sequence
MTVGKSSKMLQHIDCRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGVPAGVPMPQAPAGLAGPIRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPSGRGGPPPPMGRGAPPPGMMAPPPGMRPPMGPPMGMPPGRGAPMGMPPPGMRPPPPGMRGPPPPGMRPPRP

Gene
SNRPB
Protein
Small nuclear ribonucleoprotein-associated protein B'
Organism
Erinaceus europaeus
Length
240 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
24.592 kDa
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGLRPPRP

Gene
Snrpb
Protein
Small nuclear ribonucleoprotein-associated protein B
Organism
Mus musculus
Length
231 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:19470752).
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
23.656 kDa
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGLPPGRGTPMGMPPPGMRPPPPGMRGLL

Gene
Snrpb
Protein
Small nuclear ribonucleoprotein-associated protein B
Organism
Rattus norvegicus
Length
231 amino acids
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Similarity
Belongs to the snRNP SmB/SmN family.
Mass
23.656 kDa
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL