smc2

Structural maintenance of chromosomes protein 2

1203 amino acids

Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Belongs to the SMC family. SMC2 subfamily.

136.342 kDa

MHVKSIIIDGFKSYAQRTEINGFDPLFNAITGLNGSGKSNILDSICFLLGISNLTQVRASNLQDLVYKNGQAGITKATVSITFDNYDKKQSPLGFEAHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILAMIEEAAGTRMYECKKIAAQKTIEKKEAKLKEIQTILEEEITPTIHKLKEERSSYLEYQKIMREIEHLSRLYVAYQFVCAEETKVRSAEELKEMQDSILKLQDTMAENERKVKELGKEIAELEKMRDQEVGGALRSLEEALSEAQRADTKVQSALDLKKQNMKAEREKKRKELVKSMEEDAKVLTAKEKEVKKITDGLSSLQEASQKDVEAFTSAQQHFNAVSAGLSSNEDGEEATLAGQMMACKNETSKAETEAKQAQMKLKHAQQELKTKQAEVKKMDGGYKKDNEAFEAVKKSKEKLEVEMKKLNYEDGREEQLLEKRRGLSRDVNRLREAYESLMARFPNLQFEYKDPEKNWDSDRVKGLVASLISIKDVSTATALEVVAGGRLYNVVVDTEVTGKKLLEKGELKRRFTIIPLNKISARCLGKDTVNVAKNLVGADNVNLALSLVGYESELQKAMEYVFGTTLVCDTMDNAKKVTFDKRIMTKTVTLGGDTFDPQGTLSGGARSQNASVLVRLQELKDVQDELKAKETELQEVEKELMTLKNTVERYRQLKQQWEMKSEEAELLQTKLQQSSYHKQQEELDSLKQTIEESEETLKNTKEVQKKAEEKFKVLEHKMKNAEAERERELKEAQQKLDTAKKKADASNKKMKEKQQEVDALVLELEELKREQTTYKQQIETVDEAMKAYQEQADSMASEVSKNKEAVKKAQDELAKQKEIIMGHDKEIKTKSSEAGKLRENNNDLQLKIKELEHNISKHKKDSADAAAKVAKMLNDYEWIASEKHLFGQANTAYDFKTNNPKEAGQRLHKLQEKKEKLGRNVNMRAMNMLTQAEERYNDLMKRKRIVENDKSKILTTIEELDQKKNEALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQSVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILAMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFRHSQFIVVSLKDGMFNNANVLFKTKFVDGVSTVARFAQNQNGGSSAGQQRSDKSKTKERRNRMEVDK

SMC2

Structural maintenance of chromosomes protein 2

1197 amino acids

Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Belongs to the SMC family. SMC2 subfamily.

135.656 kDa

MHIKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLLAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALNHEIEELEKRKDKETGGILRSLEDALAEAQRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEKNWNRNCVKGLVASLISVKDTSATTALELVAGERLYNVVVDTEVTGKKLLERGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVEYKPELQKAMEFVFGTTFVCDNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKHKREAEDGAAKVSKMLKDYDWINAERHLFGQPNSAYDFKTNNPKEAGQRLQKLQEMKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILTTIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQCQNGKISKEAKSKAKPPKGAHVEV

Smc2

Structural maintenance of chromosomes protein 2

1191 amino acids

Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).

Belongs to the SMC family. SMC2 subfamily.

134.239 kDa

MYVKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEAHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLRAEDTKERSAGELKEMQDKIVNLQEVLSENEKKIKALNCEIEELERRKDKETGGKLKSLEDACAEAQRVNTKSQSAFDLKKKNLASEETKRKELQNSMAEDSKALAAKEKEVKKITDGLHGLQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMIACKNDISKAQTEAKQAQMKLKHAQQELKSKQAEVKKMDSGYKKDQDAFEAVKKAKEKLETEMKKLNYEENKEEKLLEKHRQLSRDINNLKGKHEALLAKFPNLQFAYKDPEKNWNRNSVKGLVASLINVKDNSTATALEVVAGERLYNVVVDTEVTAKKLLEKGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVDYKPELQKGMEFVFGTTFVCNNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQEVKDVQDELRTKENELRALEEELAGLKNVAEKYRQLKQQWEMKTEEGDLLQTKLQQSSYHKQQEELDALKKTIEESEETLKSTKEIQKKAEEKYEALENKMKNAEAEREKELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHASNEQQLDAVNEAIKAYEGQIEKMAAEVAKNKESVNKAQDELMKQKQIITAQDNIIKDKCAEVAKHNLQNNESQLKIKELDHSISKHKREADDAAAKVSKMLSDYDWINAEKHLFGQPNSAYDFKTNNPKEAGQRLQKLQEVKEKLGRNVNLRAMNVLTEAEERYNDLMKKKRIVENDKSKILATIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQSQAGKIPKEAKSRGKEPN

SMC2

Structural maintenance of chromosomes protein 2

1189 amino acids

Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Belongs to the SMC family. SMC2 subfamily.

134.941 kDa

MYIKSIVLEGFKSYAQRTEIRDFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASSLQDLVYKNGQAGVNKATVSITFDNSDKKNSPLGFENNDEITITRQVIVGGRNKYLINGMNASNNRVQDLFGSVGLNVNNPHFLIMQGQITKVLNMKPTEILAMIEEAAGTRMYECKKITAHKTIEKKESKLDEIRRIITEEISPTLEKLKEARASYLEYQKMTREVENLRRIYVAFQYVRAEEIKDRSTNALKEAQANKKKIFESMAENEKKVKELAQQIEETEKKNNEEFGAKLHSLEAAFSELQRVDAKVRSDLDHRKQNLNSEENRLKELIKIMQEEFKAFTSKEKEIKKIKEGLNGLQEESKKDAEALASAQQHFNAVSAGLSSNDSGQGTSLADQMMTCKNEISKAATEAKQAQMKLKYAQQELKTKQAEVKKMDGSYKEDQEAFEAIRKTKEKLQDEMKKLKYEEAEQEAHLAKKKQLSSEISSLRELCESIEAKHPYLRFEYKNPEKNWNPNCVKGLVVTLITVKDISTSKALEAVAGGKLYNIVVDTEATGKKILEKGQLKHRYTIIPLSKISANSIGHEIISLAKNLIGHREVHIAISLIDYNSELQKAMEYVFGTTLVCSSMDNAKKVTFDKRIMRKTVTLQGDIFDPQGTLSGGASSHVTPILSKLKTMRDAEDELKIKTSQLEATEKELANLKNMAEKYQHLKQQWEMKSEEAELLQTKIQQSAYHKQQEDLLALKKTIAECEETLKKTEESQRKAEEEYKALENKMKNAEAERGKEIKNAQQKLNSAKKKADDSSRKMKEKQQEVEALVLELEQLKQEQASYKQQSEAAQQAIASLKEQVSALEAEAVKTRESLKNAENELSSEKGLMEERTKDIKAKSAKIEKYREQNNELQLSINALEHDINKYQQETADASSTLDKLLKEYKWIASEKELFGQADTTYDFEANNPKETGQKLQKLLTKKEKLEKSLNMRAMNLLSEAEERYNDLMKKKRMVENDKIKILATIEELDRKKNKALHIAWEKVNKDFGSIFSMLLPGAKAMLVPSKKQNILDGLEFRVGLGDIWKENLTELSGGQRSLAALSLILAILLFKPAPIYILDEVDAALDLSHTQNIGQMLHAHFKQSQFLVVSLKDGMFNNANVLYRTKFVDGISTVSRHCQLKKKQPLSEASNNKDE

smc2

Structural maintenance of chromosomes protein 2

1184 amino acids

Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).

Belongs to the SMC family. SMC2 subfamily.

135.084 kDa

MYIEDIIIDGFKSYANRTVIEGFDPTFNAITGLNGSGKSNILDSICFVLGISNLSQVRVDSLQELVYKKGQAGITKASVTITFNNSDKKQSPAGYEHLDKITVTRQVAIGGRNKYLINGHNAQLSRVQDLFHSVQLNVNNPHFLIMQGRITKVLNMKPPEILAMIEEAAGTRMFEMKKNSALNTIEKKQKKVDEITKVLAEEITPTLDKLRGERTSYMKFTNNQTLIDRLQRFIIAYEYYTYEKKLESSEFESFKAEIDKGQKRKKDLTLKSTDLKAKISELAKQREKETNLEEMDQQEQKLSKELVKYQTSHKHQKESLDKEEGAINNLANTREEIKQSIQQKQKEKQSMEKKIQSIVEENQQINAELKTLQNKHNTMTTGISTGADGSSAAEDGSYTEQLMEAKKTAVNAASEYKQAEFRVKHLQSELIAKRKAITQEQTDHKKLQAEQELVEREIQQLTRSIQELQLDNSKQQELTEKKRQLEPLVSKLREEVGNASAQLSGLEFNYTDPSKSFDRSKVKGIVANLITLKDVETATALEICASGKLYNIVIEDDETGKALLSKGQLKRRVTLLPLNKVEGRSIDPQKIKNAQKIAPNGAVKPAIEFVEYDKELQPAMNFVFGSTFIATDKKYAQKAAFDSSIKVRTISLEGDEYNPAGSLTGGSRPPSGSILTQIQRLNENNRCLRENQSQLEHINFELVQLKSVTDRFKQLEQQLNIKQHAASLIAQRFQLNPHHQLLESIKEMEKSIESDTQLITNSMIKEKEALEKVKQLESQVNDFQSIRESQLKDLEKKIQITKEKCIKSNKIVKGEQVFIEKLDLEIQEMDNELENLSKETQGNQGTISKMRKDVDTLARSISETNKQIQDIRETLSEIRKDMAQKNDAIRSLHQELEKIQSEITEIDMSTEKLKSRMNRVDKDRQEASKWLEAAIKKHTWIKNEKQLFNRPGSDFDFNATDPSKANSEYIKLQEEQEKLSKTINRKVMSMFEKAEQEYQELMEKKKIIENDKSKIEHVIRELDEKKNESLRTTWKKVNKDFGSIFSTLLPGTSAKLEPPEGQNELFGLEVKVAFGDVWKETLSELSGGQKSLLALSLILSLLLFKPAPMYILDEIDAALDLSHTQNIGMMLKQHFTSSQFIVVSLKEGMFTNANVLFETKFIDGVSKVHRTVFNKKDKQVGKKK

SMC2

Structural maintenance of chromosomes protein 2

1170 amino acids

Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Belongs to the SMC family. SMC2 subfamily.

133.928 kDa

MKVEELIIDGFKSYATRTVITDWDPQFNAITGLNGSGKSNILDAICFVLGIASMSTVRASSLQDLIYKRGQAGVTKASVTIVFDNTDKSNSPIGFTNSPQISVTRQVVLGGTSKYLINGHRAPQQSVLQLFQSVQLNINNPNFLIMQGKITKVLNMKPSEILSLIEEAAGTKMFEDRREKAERTMSKKETKLQENRTLLTEEIEPKLEKLRNEKRMFLEFQSTQTDLEKTERIVVSYEYYNIKHKHTSIRETLENGETRMKMLNEFVKKTSEEIDSLNEDVEEIKLQKEKELHKEGTISKLENKENGLLNEISRLKTSLSIKVENLNDTTEKSKALESEIASSSAKLIEKKSAYANTEKDYKMVQEQLSKQRDLYKRKEELVSTLTTGISSTGAADGGYNAQLAKAKTELNEVSLAIKKSSMKMELLKKELLTIEPKLKEATKDNELNVKHVKQCQETCDKLRARLVEYGFDPSRIKDLKQREDKLKSHYYQTCKNSEYLKRRVTNLEFNYTKPYPNFEASFVHGVVGQLFQIDNDNIRYATALQTCAGGRLFNVVVQDSQTATQLLERGRLRKRVTIIPLDKIYTRPISSQVLDLAKKIAPGKVELAINLIRFDESITKAMEFIFGNSLICEDPETAKKITFHPKIRARSITLQGDVYDPEGTLSGGSRNTSESLLVDIQKYNQIQKQIETIQADLNHVTEELQTQYATSQKTKTIQSDLNLSLHKLDLAKRNLDANPSSQIIARNEEILRDIGECENEIKTKQMSLKKCQEEVSTIEKDMKEYDSDKGSKLNELKKELKLLAKELEEQESESERKYDLFQNLELETEQLSSELDSNKTLLHNHLKSIESLKLENSDLEGKIRGVEDDLVTVQTELNEEKKRLMDIDDELNELETLIKKKQDEKKSSELELQKLVHDLNKYKSNTNNMEKIIEDLRQKHEFLEDFDLVRNIVKQNEGIDLDTYRERSKQLNEKFQELRKKVNPNIMNMIENVEKKEAALKTMIKTIEKDKMKIQETISKLNEYKRETLVKTWEKVTLDFGNIFADLLPNSFAKLVPCEGKDVTQGLEVKVKLGNIWKESLIELSGGQRSLIALSLIMALLQFRPAPMYILDEVDAALDLSHTQNIGHLIKTRFKGSQFIVVSLKEGMFANANRVFRTRFQDGTSVVSIM