smarcal1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

960 amino acids

ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA (By similarity).

Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.

106.531 kDa

MSVCLTEEQKRKIEENRQRALARRAERLAAQQNTLKQTNNSHSTLFNIQKSTVEQGALFSGQRTNVTAACMAPLQQGSNNKYAFQKTSSGGSAASSLPGTAENKPQAGGNGPCDYKVPADPAQDFTSSKNLTGKYVAPKAHCVSSVPSFNDTPNPRQLNPACTTQEQEKPKNSSYSYSRPDSDTACDKFTAGPGPGPIRNTTAISKFYGANPGIKPALPVSNKTVSEVRDRGVTGSSVEAVPVKKASSSTRGRCVKHMEGRFRVEVGYSAELIALFKTIPSKAYDPATKMWNFGLEDYASLMSEVQRVQSVELKALEGMEGVQIAPPPTSGSGTNINALLAMCNNWQRPNATLRGRCILISRSRFEMEIGYHTEIIGLFKQMNTRNYDTKTRKWSFMLEDYQKLMESVRNIQQVEVEPLPRPVLQAFAPQFEKTTISLAEIEDVDLSHVDSKLIGNLMPFQRDGVNFAISREGRLLLADDMGLGKTIQAICIAAYYRKEWPLLVVAPSSVRFTWAEAFHRWLPSLNPESVNVIVTGRDSQSANLINIISFDLLGKMDKQIAANFKVIIIDESHFLKNVKTARCKAAMPLLKSAKRVMLLSGTPAMSRPAELYTQIAAVRPTFFPRFHDFGIRYCDAKQMPWGWDYSGSSNLNELKLLLEESIMIRRLKSEVLSQLPAKQRKMVVVAPEGITAKTKAALAAAAKEMAKGFKSKVQEKEALLLFYNRTAEAKIRSVLEYIIDLLESGREKFLVFAHHKLVLDNICEELGKKEVPYIRIDGNTSSADRQSLCHKFQFSEKSCVAVLSITAANMGLTLSSADLVVFAELFWNPGVLIQAEDRVHRIGQTSSVNIHYLVAKGTADDYLWPMIQEKIKVLGQAGLSEANFSETTESTDYFYKDPKQKTIYDLFQRSFSEQGAENDSDEALLLEACEEVDLGESTCGPTDYSGNACKRRKIDDYFAL

SMARCAL1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

954 amino acids

ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.

Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.

105.938 kDa

MSLPLTEEQRKKIEENRQKALARRAEKLLAEQHQRTSSGTSIAGNPFQAKQGPSQNFPRESCKPVSHGVIFKQQNLSSSSNADQRPHDSHSFQAKGIWKKPEEMPTACPGHSPRSQMALTGISPPLAQSPPEVPKQQLLSYELGQGHAQASPEIRFTPFANPTHKPLAKPKSSQETPAHSSGQPPRDAKLEAKTAKASPSGQNISYIHSSSESVTPRTEGRLQQKSGSSVQKGVNSQKGKCVRNGDRFQVLIGYNAELIAVFKTLPSKNYDPDTKTWNFSMNDYSALMKAAQSLPTVNLQPLEWAYGSSESPSTSSEGQAGLPSAPSLSFVKGRCMLISRAYFEADISYSQDLIALFKQMDSRRYDVKTRKWSFLLEEHSKLIAKVRCLPQVQLDPLPTTLTLAFASQLKKTSLSLTPDVPEADLSEVDPKLVSNLMPFQRAGVNFAIAKGGRLLLADDMGLGKTIQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPDCINVVVTGKDRLTAGLINIVSFDLLSKLEKQLKTPFKVVIIDESHFLKNSRTARCRAAMPVLKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRMPWGWDYSGSSNLGELKLLLEEAVMLRRLKSDVLSQLPAKQRKIVVIAPGRINARTRAALDAAAKEMTTKDKTKQQQKDALILFFNRTAEAKIPSVIEYILDLLESGREKFLVFAHHKVVLDAITQELERKHVQHIRIDGSTSSAEREDLCQQFQLSERHAVAVLSITAANMGLTFSSADLVVFAELFWNPGVLIQAEDRVHRIGQTSSVGIHYLVAKGTADDYLWPLIQEKIKVLAEAGLSETNFSEMTESTDYLYKDPKQQKIYDLFQKSFEKEGSDMELLEAAESFDPGSASGTSGSSSQNMGDTLDESSLTASPQKKRRFEFFDNWDSFTSPL

smarcal1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

942 amino acids

ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA (By similarity).

Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.

103.733 kDa

MSVCLTEEQKRKIEENRQRALARRAERLAAQQNSQTNRSLSAPLNAQIPSGQQGVLPSAQSINATGTSRAANSKYAFQKSPSGGNTAPSVPGAAGNKVQAVGNRSHDSKSLTDPAKDVKGNYTVPEAQSVPSGPSNAPNPRHLYPAGTTPGQESAKHSNSYSRPEPLTACDNDTTGPGPLRSTTTITKFYGAGPGSKPAVPVSNKTVSEGRERGVTGSAAEAVPAKKASGATRGRCVKHAESRFRVEVGYSAELIALFKTIPSKNYDPATKMWNFGLEDYASLMSEVQQLQSVELKALEGMEGVQIAPPPATGGGTNINALLAMCNNWQRPSATLRGRCILVSRSRFEMEIGYHAEIIGLFKQMNTRNYDTKTRKWSFMLEDYQKLMESVRNIQQVEVEPLPRPVLQAFAPQFGKTTIIREEIPEVDLSQVDSKLGSNLMPFQRDGVNFAVSREGRLLLADDMGLGKTIQAICIAAYYRKEWPLLVVAPSSVRFTWAEAFQRWLPSIRPESVNVIVTGRDSQSASLINIVSFDLLGKMDKQIAATFQVIIIDESHFLKNVKTARCKAAMPLLKSAKRVMLLSGTPAMSRPAELYTQIAAVRPSFFPRFHDFGIRYCDAKQMPWGWDYSGSSNLNELKLLLEESIMIRRLKSEVLSQLPAKQRKMVVVAPEGITAKTKAALAAAAKEMAKGFKSKVQEKEALLLFYNRTAEAKIRSVLEYIMDLLESGREKFLVFAHHKLVLDHICEELGKKDVPYIRIDGNTSSADRQSLCHKFQMSEKSCVAVLSITAANMGLTLSSADLVVFAELFWNPGVLIQAEDRVHRIGQTSSVNIHYLVAKGTADDYLWPMIQEKIKVLGQAGLSEANFSETTESTDYFYKDPKQKTIYDLFQRSFSEEGAETNADEALLLEACEEADLGDAVCSPTDYSGNSCKRRKIDEYFAL

SMARCAL1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

940 amino acids

ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks (By similarity).

Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.

104.776 kDa

MSISPLKCPCLLQRSRGKIEANRQKALARRAEKLLAEQHQKPAQSKQGPSQNLPRDPSKSGSHGIFFKQQNPSSSSHGDQRPQNPHSFSPNTSEQAKGMWQRPEEMPTACPSYRPPNQVTVAGISPPLANSPPGVPSQQLWGCELGQGHPQASLETQSTPFANTTHEPLAKVKNFQETAASSCGQPPRDPELEARMARPSTSGQNISGSVMPRTEGRLQQKAGTPLHRVVGSQQGRCIRNGERFQVKIGYNEALIAVFKSLPSRSYDPATKTWNFSMTDYGPLMKAAQRLPGITLQPLEGAEGHMESPSTSSGIIAKTGLPAAPSLAFVKGQCVLISRARFEADISYSEDLIALFKQMDSRKYDVKTRKWSFLLEEYSKLMERVRGLPQVQLDPLPKTLTLFRAQLQKTSLSPVADIPEADLSRVDSKLVSSLLPFQRAGVNFAIAQRGRLLLADDMGLGKTIQAICIAAYYRKEWPLLVVVPSSVRFTWEQAFCRWLPSLNPLDINVVVTGKDRLTDGLVNIVSFDLLSKLEKQLKPPFKVVIIDESHFLKNIKTARCRAAMPLLKVAKRVILLSGTPAMSRPAELYTQILAVRPTFFPQFHAFGLRYCGAKRQPWGWDYSGSSNLGELKLLLEEAVMLRRLKGDVLSQLPAKQARWWWSPQARSTPGPEPPWMPPPRMTTKDKTKQQQKEALILFFNRTAEAKIPSIIEYILDLLESGREKFLVFAHHKVVLDAITKELERKRVQHIRIDGSTSSADRETSASSFSCPRALRGVLSITAANMGLTFSSADLVVFGELFWNPGVLMQAEDRVHRIGQLSSVSIHYLVARGTADDYLWPLIQEKIKVLGEAGLSETNFSEMTEATDYFSKDSKQQKIYNLFQKSFEEDGNDMELLEAAESFDPGSQDTGDKLDESTLTGSPVKKKRFEFFDNWDSFTSPL

Smarcal1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

910 amino acids

ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks (By similarity).

Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.

100.84 kDa

MSLPLTEEQRKKIEENRQKALARRAEKLSEQPQSAASGSSAAGPSQSKQGSLLNLLAEPSKPVGHASIFKQQNLSNSFPTDQRPHSSRCSQPSPAEETTGLWKTQGEMSTACPKPNPSPPGASNQPLLGYKSSEGQPQATWDTGASSSGPFPRDPELEAKAARPSTSRQSISDSFYVLGGKTPRTEGRPPNILQTTPQNTGFLRGACIKTGDRFRVKIGYNQELIAVFKSLPSRHYDSFTKTWDFSMSDYRALMKAVERLSTVSLKPLDEAGGSVGGQTSLPSAPSLTFVTGKCMLISRVRFEVDIGYSEAVIGLFKQMESRSYDIKTRKWSFLLEEHNKLIARSRELKQVQLDPLPKTVTLAFASQLEKTSPKLKADVPEADLSGVDAKLVSSLMPFQREGVSFAISKRGRLLLADDMGLGKTVQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPENINVVVTGKGRLTAGLVNIVSFDLLCKLERQLKTPFKVVIIDESHFLKNIKTARCRAAVPILKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRLPWGWDYSGSSNLGELKLLLEEAIMLRRLKSDVLSQLPAKQRKMVVVNPGRISSRAKAALDAAAKEMTKDKTKQQQKEALLVFFNRTAEAKIPCVVEYILDLLDSGREKFLVFAHHKVILDAVAKELERKNVQHIRIDGSTPSADREAQCQRFQLSKGHTVALLSITAANMGLTFSTADLVVFAELFWNPGVLIQAEDRVHRIGQTNSVSIHYLVAKGTADDYLWPLIQEKIKVLGEAGLSETNFSEMTEATDYVHKDPKQKTIYDLFQQSFEDDGNDMEFLEAAESFELGSTSGTSGNISQDLGDLLDEDEGSPPKKSRFEFFDNWDSFSSPF

Smarcal1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

910 amino acids

ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks (By similarity).

Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.

101.212 kDa

MSLPLTEEQRKKIEENRQKALARRAEKLWAEQPQSTASGSSAARPSQCKQNSLLNLPAEPSKPEGHATISKGQNLNNSLPAAQRPHSSPCFQPSTAEEAKGLWKSEGKMSAACPNPSPPEVSNQQLLGSKSSEGHPQATQDTAASCPRPFPRDPKLEAKAGRPSTSGQSISDTFYALGEKTPKTDGRPAKALQTSPQKASCLRGMCLRTGDRFRVKIGYNKELIEVFKSLPSRRYDSFTKTWDFSMSDYRALMKAVERLSTVSLQPLEEVDGTGGQTSLPSAPSLTFVTGRCMLISRARFEVDIGYSEVVIALFKQMESRNYDPKTRKWNFLLEEHNKLIARSRELKQVQLDPLPKTLTLAFASQLEKTSLQSKADVPEADLSGVDAKLVSNLMPFQREGVSFAISKRGRLLLADDMGLGKTIQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPEDINVVVTGKGRLTAGLVNIVSFDLLSKLEKQLKTPFKVVIIDESHFLKNIKTARCRAAVPILKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRLPWGWDYSGSSNLGELKLLLEEAVMLRRLKSDVLSQLPAKQRKMVVVNPGRISTRAKAALDAAAKEMTKDKTKQQQKEALLVFFNRTAEAKIPCVIEYILDLLESGREKFLVFAHHKVLLDAIAKELERKNVQHIRIDGSTPSADREDLCQQFQLSKGHTVAVLSITAANMGLTFSSADLVVFAELFWNPGVLIQAEDRVHRIGQTNSVGIHYLVAKGTADDYLWPLIQEKIKVLGEAGLSETNFSEMTEATDYLYKDPKQKTIYSLFQQSFEDDGNDMEFLEAAESFELGSTSGTSGNSSQELGDITDENALADSPPKKRRFEFFDNWDSFTSPF

smarcal1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

807 amino acids

ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA (By similarity).

Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.

89.896 kDa

MSVSLTPEQQRRIEENRKKALARRAERQAQIADPGPAQNKHTQSGTTGGPAKNNQHFASDRGQSGAPTRQTQLIDINAACTKTAPPTSITAASTASSFYGQAGKPSTGEKRPPKPPEPAANIPAKKPAVYLRGRCVSHSENRFRVEVGYHADLILVFKSIPSKNYDPATKMWNFSLEDYQMLMEQVAHLPSISLKPLEGMEGLNISASTCRPKDAAAMAALMRLCQGWQKPGATIKGKCVLVSRSRLEVDIGYQADVIGIFKQMPSKSYDMKTRKWTFLLEDYGKLMADLNELPTVETEPLPHAVLQSFSSQFEKTQSQAPVPPEADLSHIDPQLTRSLMPFQRDGVNFAVSREGRLLLADDMGLGKTVQAICIAAYYRSEWPLLVVAPSSVRFTWAEAFRRWLPSVKPDSINVVVKGKDSLRSGLINIISYDLLNKMDKQPPSSPFNVIIMDESHFLKNMKTARCRAALPLLKTAKRVILLSGTPAMSRPAELYTQIQAVRPALFPRFHDFGTRYCDAKQLPWGWDYSSSSNLTELKLLLEESLMLRRLKSEVLSQLPAKQRKVVTVTTDGINSRTKAALNAAARELAKGYHNKSQEKEALLVFFNHTAEAKIRAIMEYISDMLECGREKFLVFAHHKLVLDSITKELGEKSISFIRIDGSTPSAERQLLCERFQASQQSCVAVLSITAANMGLTLHSAALVVFAELFWNPGVLIQAEDRVHRIGQTSNVDIHYLVAKGTADDYLWPMIQAKMNVLEQVGLSESNISENAESASFHSRDRQQLTITEMFQRSFDEDEMLALMDQDP