SLC2A2

Gene

SLC2A2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Gallus gallus

Length

533 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. Also able to mediate the transport of dehydroascorbate.

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.699 kDa

Sequence

MDGKSKMQAEKHLTGTLVLSVFTAVLGFFQYGYSLGVINAPQKVIEAHYGRMLGAIPMVRHATNTSRDNATITVTIPGTEAWGSSEGTLAPSAGFEDPTVSPHILTMYWSLSVSMFAVGGMVSSFTVGWIGDRLGRVKAMLVVNVLSIAGNLLMGLAKMGPSHILIIAGRAITGLYCGLSSGLVPMYVSEVSPTALRGALGTLHQLAIVTGILISQVLGLDFLLGNDELWPLLLGLSGVAALLQFFLLLLCPESPRYLYIKLGKVEEAKKSLKRLRGNCDPMKEIAEMEKEKQEAASEKRVSIGQLFSSSKYRQAVIVALMVQISQQFSGINAIFYYSTNIFQRAGVGQPVYATIGVGVVNTVFTVISVFLVEKAGRRSLFLAGLMGMLISAVAMTVGLVLLSQFAWMSYVSMVAIFLFVIFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFCNWACNFIVGMCFQYIADLCGPYVFVVFAVLLLVFFLFAYLKVPETKGKSFEEIAAAFRRKKLPAKSMTELEDLRGGEEA

Protein

Solute carrier family 2, facilitated glucose transporter member 2: SLC2A2

Gene

SLC2A2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Gallus gallus

Length

533 amino acids

Function

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.699 kDa

Sequence

Protein

Solute carrier family 2, facilitated glucose transporter member 2: SLC2A2

Gene

SLC2A2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Homo sapiens

Length

524 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose (PubMed:8027028, PubMed:16186102, PubMed:23396969, PubMed:28083649). Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell (PubMed:8027028). May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (PubMed:3399500). Also able to mediate the transport of dehydroascorbate (PubMed:23396969).

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.49 kDa

Sequence

MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV

Protein

Solute carrier family 2, facilitated glucose transporter member 2: SLC2A2

Gene

SLC2A2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Homo sapiens

Length

524 amino acids

Function

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.49 kDa

Sequence

Protein

Solute carrier family 2, facilitated glucose transporter member 2: SLC2A2

Gene

SLC2A2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Sus scrofa

Length

524 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate.

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.263 kDa

Sequence

MTEDKITGTLVFAVLTAVLGSFQFGYDIGVINAPQQVIITHYRHVLGVPLDDRKAINSYAINSTEELPTGPYPGDPTPTSWAEEETTASASLIIMLWSLSVSIFAIGGMIASFFGGMLGDRLGRIKAMLVANILSLVGALLMWFSKLGPSHILIISGRGISGLYCGLISGLVPMYIGEIAPTKFRGAIGALHQLAIVTGILVSQIIGLDFLLGNHELWHILLGLSAVPAVLQSLMLFFCPESPRYLYIKLDEEAKARKSLKKLRGSDDVTKDITEMRKEREEASSEKKVSIIQLFTNSSYRQPILVALMLHMAQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAINTIFTALSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLDKLPWMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAMAAFSNWTCNFIIALCFQYIADFCGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEIAAEFQKKSGSAQSPKAAVEMEFLGATETV

Protein

Solute carrier family 2, facilitated glucose transporter member 2: SLC2A2

Gene

Slc2a2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Mus musculus

Length

523 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate.

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.107 kDa

Sequence

MSEDKITGTLAFTVFTAVLSSFQFGYDIGVINAPQEVIISHYRHVLGVPLDDRKAAINYDVNGTDTPLTVTPAYTTPAPWDEEETEGSAHIVTMLWSLSVSSFAVGGMVASFFGGWLGDKLGRIKAMLAANSLSLTGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTLHQLALVTGILISQIAGLSFILGNQDHWHILLGLSAVPALLQCLLLLFCPESPRYLYIKLEEEVRAKKSLKRLRGTEDVTKDINEMKKEKEEASTEQKVSVIQLFTDANYRQPILVALMLHMAQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLDKFAWMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFVIALCFQYIADFLGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEIAAEFRKKSGSAPPRKAAVQMEFLASSESV

Protein

Solute carrier family 2, facilitated glucose transporter member 2: Slc2a2

Gene

Slc2a2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Mus musculus

Length

523 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate.

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.107 kDa

Sequence

Protein

Solute carrier family 2, facilitated glucose transporter member 2: Slc2a2

Gene

Slc2a2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Rattus norvegicus

Length

522 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose (PubMed:3048704). Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell (PubMed:3048704). May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (By similarity). Also able to mediate the transport of dehydroascorbate (By similarity).

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

57.086 kDa

Sequence

MSEDKITGTLAFTVFTAVLGSFQFGYDIGVINAPQEVIISHYRHVLGVPLDDRRATINYDINGTDTPLIVTPAHTTPDAWEEETEGSAHIVTMLWSLSVSSFAVGGMVASFFGGWLGDKLGRIKAMLAANSLSLTGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTLHQLALVTGILISQIAGLSFILGNQDYWHILLGLSAVPALLQCLLLLFCPESPRYLYLNLEEEVRAKKSLKRLRGTEDITKDINEMRKEKEEASTEQKVSVIQLFTDPNYRQPIVVALMLHLAQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLAGMIGMFFCAVFMSLGLVLLDKFTWMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFIIALCFQYIADFLGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFDEIAAEFRKKSGSAPPRKATVQMEFLGSSETV

Protein

Solute carrier family 2, facilitated glucose transporter member 2: Slc2a2

Gene

SLC2A2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Bos taurus

Length

510 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate.

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

56.06 kDa

Sequence

MTEDKVTGTLVLAVFTAVLSSFQFGYDIGVINAPQQVIITHYRHVLGVSLDDRIAINNYALNSTEELPTSLGDPTPVSWAEEETMTSASLITMFWSLSVSSFAVGGMIASFFGGLLGDKLGRIKALLVANILSLVGALLMGFSKLGPSHILIISGRGISGLYCGLISGLIPMYIGEIAPTTLRGAIGALHQLAIVTGILISQIVGLDFILGNHELWHILLGLSAVPAILQCLLLFFCPESPRYLYIKLDEEAKAKKSLKRLRGSDDITKDITEMRKEREEASNEKKVSIIQLFTNASYRQPILVALMLHAAQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAVNTVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLSKFPWMNYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTGNFIIALCFQYIADFCGPYVFFLLLVWSWPLFCSHFLKFQKPKENPLRKSQQSSERRGVQLKRQKLL

Protein

Solute carrier family 2, facilitated glucose transporter member 2: SLC2A2

Gene

SLC2A2

Protein

Solute carrier family 2, facilitated glucose transporter member 2

Organism

Bos taurus

Length

510 amino acids

Function

Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate.

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Mass

56.06 kDa

Sequence

Protein

Solute carrier family 2, facilitated glucose transporter member 2: SLC2A2