SEF1

Putative transcription factor SEF1

1148 amino acids

Putative transcription factor that seems to be involved in the sporulation process. Suppresses the lethal phenotype of RPM2 deletion.

127.992 kDa

MVKDNRDSDQDQDFSSAHMKRQPEQQQLQQHQFPSKKQRISHHDDSHQINHRPVTSCTHCRQHKIKCDASQNFPHPCSRCEKIGLHCEINPQFRPKKGSQLQLLRQDVDEIKSKLDTLLANDSVFVHLLQQIPMGNSLLNKLNLHPTPTPGTIIPNPDSSPSSGSPTSSAAQRDSKVSVQTYLSREPQLLQANQGSNTNKFKANNEASSHMTLRASSLAQDSKGLVATEPNKLPPLLNDSALPNNSKESLPPALQMAFYKNNSAGNTPNGPFSPIQKTYSPHTTSTTVTTTTNQPPFAATSHVATNNNADRTKTPVVATTTTMPLLPSPHANVDEFVLGDISISIEKANRLHHIFVTRYLPYFPIMYSNNATELYSQSQLLFWTVMLTACLSDPEPTMYCKLSSLIKQLAIETCWIRTPRSTHISQALLILCIWPLPNQKVLDDCSYRFVGLAKSLSYQLGLHRGEFISEFTRTQTSMPNAEKWRTRTWLGIFFAELCWASILGLPPTSQTDYLLEKALSCGDEESEEDNNDSIDNNNNDKRNKKDEPHVESKYKLPGSFRRLLSLANFQAKLSHIIGSSTSSPDGLLEPKYRAETLSILGKELDLLAKTLNFQSDDTVNIYFLYVKLTVCCFAFLPETPPTDQIPYVTEAYLTATKIVTLLNNLLETHQLIELPIYIRQAATFSALILFKLQLTPLLPDKYFDSARQSVVTIHRLYRNQLTAWATSVENDISRTASMLEKLNFVLIMHPEVFVEEDGIISRMRSHLTGSLFYDLVWCVHEARRREMDPEYNKQALEKAAKKRKFSSNGIYNGTSSTGGITDRKLYPLPLYNHISRDDFETVTKTTPSGTTVTTLVPTKNALKQAEKLAKTNNGDSDGSIMEINGIPLSMLGETGSVKFQSLFANTSNSNDYNNNRTLLDASNDISIPSNSIYPVASVPASNNNPQSTKVDYYSNGPSVIPDLSMKRSVSTPVNHFPASVPGLRNHPVGNLSNNVTLGIDHPIPREHSNLQNVTMNYNNQFSNANAIGRSQSSMSHSRTPIASKSNNMTDLHSVVSDPGSSKSTAYPPLSLFSKSNDINSNKTNQRFSTGTNTVTSSNFQTIDNENNVKTPGNKLTDFFQQQSAGWIEGNSSNDDFFGWFDMNMEQGF

SEF1

Putative transcription factor SEF1

1119 amino acids

Putative transcription factor. Suppresses the lethal phenotype of RPM2 deletion.

123.242 kDa

MGDPVSSKRKSSVSDAVSTSKRQHQQVKVEDVNVPLSSREHSPGPQLHTQQSYYGNGTDGASESALTQSRNNNGATSVVAISDATQNGEDSSNISNNSNAVSKGKAVVNAGHRPVTSCTHCRQHKIKCNASEKFPAPCSRCERMGLHCEIDPQFRPKKGSQLQSLRNDVDELKVKIEYLTRNESLIAKALKQSNIGQNLLQAIKSVDFSYRVAGPTQGQVAKNKISVQTYLTNEPQLLQDSQTTTTNPTTSSNSKVVTPTGSDHSPASHNGGSLSSGKPQLLNDSVPANTKDRLPPVLQIALKRLSQQISSSSPQNSSPTTTGHSPANDLSSSKQHVVATTNAMPLLPSPHANIDEFVLGDVHISIEKATELHNIFVARFLPYFPIMQSNSATELYSQSQLLFWTVILTASLSDPEPTLYNKLSSLIKQLAIETCWIRTPRSTHISQALLILCNWPLPNQKVLDDCSYRFVGLAKSLSFQLGLHRGKFMTEFTRTQTSLPEAEKWRTRTWLGIFFAEQLWASILGLPPTSQTDYLIEKARLGDDGELPPILRKLICLANFQGKLCNVMGTSVVSPDGLMDARERAGSLAILERELERLDVKLKFQEDAAVEIYFLYIKLMICCFAFLPETPTEDQTKYVTEAYLCATKIITLLTKLLETQQLIELPIYIRHSATYSALILFKLYLTPLLLDKYVDSARQSIVTVHRLYRNQLTAWAASVENDISRTASVLEKLNFVLVTHPEVFIEEEGIISRMRSHLTGTLFYDLVWCVHEARRRQMDPNYDAEAAKRNKEKWFKNRRKLYPLPFYNQISKEDFETITQTTPGGTTVTTLVPTKSAIKQAKQLAQSQGDQNGPVTHINGIPLSMLDETGSVNIEGLLANANLNLSNEHSTVLASSSSTATRLNADNPTTDTNKFNVQTVFTHNIKKSSKSSDTPTNKPKFNSTSSIPTATPTSEQRAAHNTKTSASILTGDPNSLFSMNNSLQANIQLNKTLSADSNGTSNNNIPNSTAPLNTPDTNSFNSLTRSPDAPSYGNMNVFYNAANQGTNMNTLYSQSVPNAPQGISAPLSAQPVNVTNIPNGNVNSELDDFFLRQSAGWIEGNSSNDDFLGWFDMNMAPEF

SEF1

Putative transcription factor SEF1

1051 amino acids

Putative transcription factor.

115.375 kDa

MSTDVSERGAEAGSSSGLLSSPCVGDGSDSAQMKKRNTETAGMKARKKLRSEESGLSTLVSIASFGGQASPDRSKVSKQQNGASGHRPVTSCTHCRQHKIKCNASENFPSSCSRCERMGLQCEIDPQFRPKKGSQLQNLKNEIEELKTKLEFLLRSEGILSSAMRNSDLGRQILQAIKLQDSPQQQTGISVQTYLASEPELLKSESSVKSSVNTPSGSYSASAVDVSRAKTNSVPPLLNDSAPANSNRESLPPVLQMALKYHNSSHNTPIDTPSSHTTPMLSPEVKKPVVATTNAMPLLPSPYANIDEFVLGDVHIPIDKAKELHHIFVKKYLPYFPIMTTDSVTELYSQSQLLFWTIMLTACLSDPEPTLYNSLASLIKQLAIETCWIRTPRSTHISQALLILCNWPLPNQKVLDDCSYRFVGLAKSLSFQLGLHRGEFMSEFTRTQTLMPDAEKWRTRTWLGIFFAEQCWSSILGLPSTSQTDYFIEQARRGKFDLPVRFHRLLCLAHFQASLSNIMGSSVESPDGLMDAKERGSSLAALERELARLHSELKFDSDPVVEMYYLYAKLMIYCFAFLPETPKADQTQYVTEAYLAATRIITLLTKTLEDTQLIELPIYVRQSVTYAALILFKLHLTPYLPEKYVDSARQSIVTVHRLYRNQLTAWATGVENDISRTASVLEKLNFVLITYPEIFVEEDGIISRMRSHLTGTLFYDLIYCVHEARRRQVDSEYNEMLEKNRKEQPVHTAATGSQDTEKRAPKRRLFPLPFYNQISKEDFETITQTTPGGTTVTTLVPTKNAILQAKKLQRSQGGQKGEPIRSINGIPLAMLDATGSVNGALVGDNLNSSVPQAAVAASAPPEPAAVAATVPPEPAPAPGGQSYPLFQPLYVQPAANVPMQRSASASVAEALPFRRPGMPKITSESIASGNPNSLFGNDGSPFPAIAQKSAKPAPPAKPDGQPAKQPAPYPNLNVFLGANASARMASYSSLMDAADPLAPDPDRAPLAAPGPLAHISELDSFFLQQSAGWIEGSSSNDDFLGWYDINMAPEF

SEF1

Transcriptional regulatory protein SEF1

917 amino acids

Transcription factor which plays an essential role in virulence by activating the transcription of iron uptake genes such as FRE7 in iron-poor environments such as the host bloodstream and internal organs. Promotes commensalism in a mouse model of gastrointestinal infection.

103.901 kDa

MKFEKGKVRILPKPSPTPTNPQTPLPLLPAQTKPVNSKRKSAASTPGNESKKSRKSNSTASTPNSATPTSVGTPPQKTSKPTGHRPVTSCTFCRQHKIKCNASDNYPNPCERCKKMGLKCEIDPEFRPRKGSQIQSLKSDVDELKAKIEMLTKNESLLTQALNQHNLNHASQQQQSSGSQSQQQHPPNPQRALSYTSANSSPQVAFSNASPIPSVTSIQQNAPLTHENSDNSPYALNTPENIEELQPISEFILGDVTLPLNRANELHDKFMTTHLPFLPIIISRSATELYHKSQLLFWAVILTASLSEPEPKLYMSLASLIKQLAIETCWIKTPRSTHVIQALIILSIWPLPNEKVLDDCSYRFVGLAKNLSLQLGLHRGGEFIQEFSRNQVSLGPDAERWRTRSWLAVFFCEQFWSSLLGLPPSINTTDYLLENARVDKSLPKNFRCLISLSIFQCKLVNIMGISVTRPDGLLEPSNRAGSLSLLDRELERLRFKLQFEEGGPIEVYYLYIKLMICCFAFLPGTPIEDQVKYVSFAYLSATRIVTIVSKMVNDISLIELPIYIRQAVTYSVFMLFKLHLSRYLIDKYVDSARQSIVTVHRLFRNTLSSWKDLQNDISRTAKVLENLNMVLYNYPEIFLNDSENEDSSIITRMRSHLTASLFYDLVWCVHEARRRSVLDKGKRQAQPNKKILPLPFYNQITKDDFKTITTTSPNGTTITTLVPTDQAMNQAKSKSFDSSKPLEINGIPLPMLEATGSTREVLDSLPSQSLPSQAPTLQQYPMQQDQQQQEPSQQQQQKHSQQSQQYQQQQQSNQQQPHLQHQRQFQQSPPPQFSMISSTPPLQQPPFILANSPLPQTYLPKIDEMNMSPEVKQENSVAPFASQITNFFDQQTSGWFNNDNQDDDFLGWFDVNMMQEK