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SDH7

Gene
SDH7
Protein
Succinate dehydrogenase assembly factor 3, mitochondrial
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
133 amino acids
Function
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDH2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. Acts together with SDHAF1 (SDH6).
Similarity
Belongs to the complex I LYR family. SDHAF3 subfamily.
Mass
15.783 kDa
Sequence
MNNKLIYRSVRFATHNSQLLLPPLVLYRRILRQHKLLPGPQREMGDQYVRNEFKLHKDIDNPLHIVGFLASWQDYLHMISNGKWKDATLSSETLEKLSPEQTVQLYELMKETQKLHQDNEIESSKDVKRNNKD

Gene
SDH7
Protein
Succinate dehydrogenase assembly factor 3, mitochondrial
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
122 amino acids
Function
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Similarity
Belongs to the complex I LYR family. SDHAF3 subfamily.
Mass
14.281 kDa
Sequence
MHPSVVRLVKPRRPERITSPILPPLPLYRAILRAHHRKLPQELRYLGDQYVKKEFKDHKKIDNPLHIVGFLTEWQDYLKQIDGGSWSHGKLSKDDLDKMSPEQIGQLHELMEATKKIGEESI

Gene
SDH7
Protein
Succinate dehydrogenase subunit 7, mitochondrial
Organism
Oryza sativa subsp. japonica
Length
90 amino acids
Mass
9.899 kDa
Sequence
MAQPAFLSALRSRLRSPQPQAPALPHLQPPRRGFHVELGAREKALLEEDTALKRFKSYKNSVKQVSKVGNILTGVVLFACAYEIVALANS