SCRN1

Gene

SCRN1

Protein

Secernin-1

Organism

Bos taurus

Length

414 amino acids

Function

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium.

Similarity

Belongs to the peptidase C69 family. Secernin subfamily.

Mass

46.202 kDa

Sequence

MAVAPPSYCFVAFPPRAKDGLVVFGKNSARPRDEVQEVVYFSAADHEPESKVECTYISINQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGATAKEALDVIVALLEEHGQGGNYYEDANSCHSFQSAFLIVDREEAWVLETVGKYWAAEKITEGVKCICNQLSLTTKIDAEHPELRSYAQSQGWWMGEDEFNFSEVFSPADDHLTCCSGRDTLEKQEESITVQTMIDVLRDKASGVCVDSESFLTTASVVSVLPQNGSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVLESDEEQGQKLRKTMLELEKQGLEAMEEILTSSDPLDPTEVGDLFYDCVDTEIKFFK

Protein

Secernin-1: SCRN1

Gene

SCRN1

Protein

Secernin-1

Organism

Homo sapiens

Length

414 amino acids

Function

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).

Similarity

Belongs to the peptidase C69 family. Secernin subfamily.

Mass

46.382 kDa

Sequence

MAAAPPSYCFVAFPPRAKDGLVVFGKNSARPRDEVQEVVYFSAADHEPESKVECTYISIDQVPRTYAIMISRPAWLWGAEMGANEHGVCIANEAINTREPAAEIEALLGMDLVRLGLERGETAKEALDVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAEKVTEGVRCICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSPVEDHLDCGAGKDSLEKQEESITVQTMMNTLRDKASGVCIDSEFFLTTASGVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIESDQEQGRKLRSTMLELEKQGLEAMEEILTSSEPLDPAEVGDLFYDCVDTEIKFFK

Protein

Secernin-1: SCRN1

Gene

Scrn1

Protein

Secernin-1

Organism

Mus musculus

Length

414 amino acids

Function

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).

Similarity

Belongs to the peptidase C69 family. Secernin subfamily.

Mass

46.326 kDa

Sequence

MSGAPPSYSFVALPPRAKDGLVVFGKNSARPRDEVQEVVYFPAVDHDAESKVECTYISIDQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGTTAKEALDIIVSLLDEHGQGGNYYEDAHSCHSFQSAYLLVDRDEAWVLETVGKYWAAERITEGVRCICNHLSLATKLDEEHPELRTYAQSQGWWTGDDEFNFAQVFSPADDRLDCCAGQDSLEKQEESITVQTMINILRDKASGVCIDSESFLTTASIVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVIESDEEQGRTLRKTMLELEKQGLEAMDEILSSPEPPDPAEVGDLFYDCVDTEMKFFK

Protein

Secernin-1: Scrn1

Gene

Scrn1

Protein

Secernin-1

Organism

Rattus norvegicus

Length

414 amino acids

Function

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).

Similarity

Belongs to the peptidase C69 family. Secernin subfamily.

Mass

46.396 kDa

Sequence

MSGAPPSYSFVALPPRAKDGLVVFGKNSARPRDEVQEVVYFPAVDHEAESKVECTYISIDQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGTTAKEALDIIVSLLDEHGQGGNYYEDAHSCHSFQSAYLLVDRDEAWVLETVGKYWAAERITEGVRCICNHLSLTTKMDEEHPELRTYAQSQGWWTGEDEFNFAQVFSPADDHLDCCAGKDSLEKQEESITVQTMINILRDKASGVCIDSESFLTTASIVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVIESDQEQGRTLRKTMLELEKQGLEAMEEILSSPEPPDPAEVGDLFYDCVDTEMKFFK

Protein

Secernin-1: Scrn1