Protein
Aminodeoxyfutalosine deaminase
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Function
Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Sequence
MRPAYDDPRTTDQPITRARPPPRAARGRRLGEEPLTEHLVDPDVPRDLHAFIAGLPKAELHVHHVGSASPRIVSELAARHADSKVPTDPEALVDYFTFTDFAHFIDVYLSVVDLIRTPEDVRLLTYEVARDMARQQVRYAELTITPFSSTRRGIDEGAFMDAIEDARKAAEAEFGTVLRWCFDIPGEAGLESAEETARLATDDRLRPEGLVSFGLGGPEIGVARPQFKPYFDRAIAAGLHSVPHAGETTGPQTVWEALIDLRAERIGHGTSSAQDPKLLAHLAERRIPLEVCPTSNIATRAVRTLDEHPIKEFVRAGVPVTINSDDPPMFGTDLNNEYAVAARLLGLDERGLADLAKNGVEASFLDAPGKARIADEIDTYTAAWLAS