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SCNN1G

Gene
SCNN1G
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Pelodiscus sinensis
Length
669 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
76.22 kDa
Sequence
MAPPYHGDTREFSMAPAKKIKAKIKKTLPVTGPQAPTVSELMHWYCMNTNTHGCRRIVVSRGRLRKFIWILLTLSAVGLILWQCAELIMSYYTASVSVTVQFQKLPFPAVTICNINPYKYSAMKEHLSELDKETKNALETLYGFSEGKSKVRRDAADWNSTGRNMQSKLLEKIPLLKFDDLFKKTATEILSGHKRKIEGSAFHQGSSMVNIGEPQDVVGFQLCDPNNSSDCAVYIFSSGVNAIQEWYKLHYMNIMAQIPLEMKVNMGYSAEDLLLTCFFDGISCDSRNFTPFHHPLYGNCYTFNSGENGTILTTSTGGSEYGLQVVLYVEEADYNPFLVTSTGAKIIVHDQDEYPFIEDIGTEIETAMATSIGMHFTRSHKLSQPYSDCTETGNDIPVANLYNKSYSLQICLHSCFQRAMVDTCGCAQYAQPLPPGAEYCNYKKYPNWMYCYYKLHEKFVKEQLGCQQICKESCSFKEWTLTTSLAQWPSSVSEDWMLRVLSWDKRQKINKMLNKTDLANLVVFYKDLNERFISENPANNLVILLSNFGGQLGLWMSCSMVCVIEIIEVFFIDSFSIVMRRRWQKMKKWWNDRKAPRPQEPPQVNAPAKEGHDNPVCTDEDLPTFNTALRLPLPQENHMPRTPPPNYSTLQLNAAFTDQLPDTLEGRSH
Protein
Amiloride-sensitive sodium channel subunit gamma: SCNN1G

Gene
Scnn1g
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Mus musculus
Length
655 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
74.635 kDa
Sequence
MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCLNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQCALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPRKRREAGSMRSTWEGTPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNRENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLVHQQNEYPFIEDVGTEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKDWWARRRTPPSTETPSSQQGQDNPALDTDDDLPTFTSAMRLPPAPEAPVPGTPPPRYNTLRLDSAFSSQLTDTQLTNEF
Protein
Amiloride-sensitive sodium channel subunit gamma: Scnn1g

Gene
SCNN1G
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Oryctolagus cuniculus
Length
653 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
74.287 kDa
Sequence
MAPGEKIKAKIKKNLPVKGPQAPTIKELMRWYCLNTNTHGCRRIVVSPGRLRRLLWIAFTLTAVGLIFWQCALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSVVRDLLADLEQETRGALKSLYGFSEVKSRKQRDTESWSPAWEGVRPKFLNLVPLLIFNRDEKGKARDFLSLGRKRKISGNIIHKASNVVQVHESKKVVGFQLCPNDSSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSATGAKVLIHRQDEYPFIEDVGTEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPIKNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLYQAFVQEELGCQSVCKQSCSFKEWALTTSLAQWPSAVSEKWLLPVLTWDQGQQINKKLNKTDWAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDSLSIVTRRQWQKAKEWWARRKAAPSAEAPSGAQGQENPALEIDDDLPTFTSALSLPPAPGAQVPGTPPPRYNTLRLERTFSQQLADTRLPDEP
Protein
Amiloride-sensitive sodium channel subunit gamma: SCNN1G

Gene
scnn1g
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Neoceratodus forsteri
Length
653 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
74.712 kDa
Sequence
MGHGRRISESIKKQLPVTGPEAPTVKNLMDWYLNNTNTHGCRRIAVSRGYLRRWIWICFTVSSVGMIFWQWTLLLMSYYTVSVSVTVQFQTLPFPAVTICNINPYRKNATSALLEELDKQTKLILKELYTSCTGCSNRKLRSVLLNEAPEEDSGVAKLLQDMPLMKFEVIKEDHVIVSELSSNRQYRINNTFITRMYNNMDLATVGEQVGFKICDANKSNCIIYTFNSGVTAILEWYRLNYLNIMAQIPNEKKLEMGYSADDLIVTCMYDGQSCDSRNFTLFQHPLHGNCYTFNSGDDGNILQTLTGGSEYGLKLTLYLENDDYNPYLFTSMGAKIIVHDQTEYPLVDDVGLEIQTATETLIGLQVTTSAKLSKPYSDCTMDGSDVLEQNLYNTSYSLQICLHSCFQTEMISNCGCAYYEQPLPSGAEYCYYEKYPGWIYCYYQLQDKFVNERLACQDICKETCNSKDWDLTKSLARWPSVASKDWVLNLLNWERGLNNTLNKNDLASIAIFYQDLNLRSLSESPANSIATLLSNMGGQLGLWMSCSIVCFLEMWEVFLVDILTIIARYWLHRGRQWWRKRKERQMQQPSPPDHDTGHHNPVCIDDEDPPTFHTAMQLPCVQTGPVPSTPPPQYNALRIQSVFDEQVSDTEVN
Protein
Amiloride-sensitive sodium channel subunit gamma: scnn1g

Gene
SCNN1G
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Bos taurus
Length
652 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
74.321 kDa
Sequence
MAPGEKIKAKIKKNLPVTGPQAPNIKELMQWYCLNTNTHGCRRIVVSRGRLRRLLWILFTLTAVALIFWQCALLISSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVRHLLADLEQETRAALKTLYGFSEITSRKRREAQSWSSVRKGTDPKFLNLAPLMAFEKGDTGKARDFFTGRKRKVNARIIHKASDVMHIHNSKEVVGFQLCSNDTSDCAVYTFSSGVNAIQEWYKLHYMNIMAQVSQEKKINMSYSADELLVTCFFDGVSCDARNFTLFHHPMYGNCYTFNNRQNETILSTSMGGSEFGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMATSIGMHLTESFKLSDPYSQCTEDWSDVQITNIYNATYSLQICLHSCFQAKMVENCGCAQYSQPLPRGADYCNYQQHPNWMYCYYQLHQAFVREELGCQSVCKEACSFKEWTLTTSLAQWPSEVSEKWLLSILTWDQSQQIKKKLNKTDLAKLLIFYKDLNQRSIMENPANSIEQLLSNIGGQLGLWMSCSVVCVIEIIEVFFIDSLSIIARHQWHKAKGWWARRRAPACPEAPRAPQGRDNPSLDIDDDLPTFTSALSLPPAPGSQVPGTPPPRYNTLRLERAFSSQLTDTQTTFPH
Protein
Amiloride-sensitive sodium channel subunit gamma: SCNN1G

Gene
Scnn1g
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Rattus norvegicus
Length
650 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
74.066 kDa
Sequence
MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCMNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQCALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKESRKRREAGSMPSTLEGTPPRFFKLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNKENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLIHQQNEYPFIEDVGMEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWHKAKDWWARRQTPPSTETPSSRQGQDNPALDTDDDLPTFTSAMRLPPAPGSTVPGTPPPRYNTLRLDRAFSSQLTDTQLTNEL
Protein
Amiloride-sensitive sodium channel subunit gamma: Scnn1g

Gene
SCNN1G
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Homo sapiens
Length
649 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
74.27 kDa
Sequence
MAPGEKIKAKIKKNLPVTGPQAPTIKELMRWYCLNTNTHGCRRIVVSRGRLRRLLWIGFTLTAVALILWQCALLVFSFYTVSVSIKVHFRKLDFPAVTICNINPYKYSTVRHLLADLEQETREALKSLYGFPESRKRREAESWNSVSEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMHIESKQVVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGVSCDARNFTLFHHPMHGNCYTFNNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESFKLSEPYSQCTEDGSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLHRAFVQEELGCQSVCKEACSFKEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDLPTFNSALHLPPALGTQVPGTPPPKYNTLRLERAFSNQLTDTQMLDEL
Protein
Amiloride-sensitive sodium channel subunit gamma: SCNN1G

Gene
SCNN1G
Protein
Amiloride-sensitive sodium channel subunit gamma
Organism
Pan troglodytes
Length
585 amino acids
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
Mass
66.99 kDa
Sequence
MAPGEKIKAKIKKNLPVTGPQAPTIKELMRWYCLNTNTHGCRRIVVSRGRLRRLLWIGFTLTAVALILWQCALLVFSFYTVSVSIKVHFRKLDFPAVTICNINPYKYSTVRHLLADLEQETREALKSLYGFPESRKRREAESWSSISEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMHIESKQVVGFQLNFTLFHHPMHGNCYTFNNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESFKLSEPYSQCTEDGSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLHRAFVQEELGCQSVCKEACSFKEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKEWWARKQAPPCPEAPRSPQGQDNPALDIDDDLPTFNSALHLPPALGTQVPGTPPPKYNTLRLERAFSNQLTDTQMLDEL
Protein
Amiloride-sensitive sodium channel subunit gamma: SCNN1G