Protein
S-adenosylmethionine carrier 1, chloroplastic/mitochondrial
Organism
Arabidopsis thaliana
Function
Transporter involved in exchange reactions through membranes. Has a low uniporter activity. Specifically mediates the transport of S-adenosylmethionine (SAM) and its closest analogs. Probably involved in the uptake of SAM in exchange for S-adenosylhomocysteine (SAHC), which is produced from SAM in the mitochondrial matrix and plastidial stroma by methyltransferase activities.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Sequence
MAPLTLSVDVKSSSATSHDVSKRVMQSSQLKINKGFFASVNTQEDKPFDFFRTLFEGFIAGGTAGVVVETALYPIDTIKTRLQAARGGGKIVLKGLYSGLAGNIAGVLPASALFVGVYEPTKQKLLKTFPDHLSAVAHLTAGAIGGLAASLIRVPTEVVKQRMQTGQFTSAPSAVRMIASKEGFRGLYAGYRSFLLRDLPFDAIQFCIYEQLCLGYKKAARRELSDPENALIGAFAGALTGAVTTPLDVIKTRLMVQGSAKQYQGIVDCVQTIVREEGAPALLKGIGPRVLWIGIGGSIFFGVLESTKRTLAQRRPNTVKETKEE