Rab3-GAP

Rab3 GTPase-activating protein regulatory subunit

1341 amino acids

Probable regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity).

Belongs to the Rab3-GAP regulatory subunit family.

151.008 kDa

MACEVKHCGEIRDFKKVQEYFGLGHDDNWLNAINHAISPTGELIAMAQGEKLAFLSTCWSSHGNGNTYVLGWCGELEDPNQIVTSLTCLPMTQNKSTDGAIEWTCVAVGLCSGMVTFYTDSGVKLFSQCCQEDPVIGVKLQSAPRHSEADSLLYIIYPRCLCFIQGQDILPTLNNCRHNVQRGALERSSYPTADVVPFQKYKFKQEREAVINDAAISTTQRPPTYDYIVQQTIGLGYFAKVHATPPRSSQVLAAGAEPYLGFFQAEEGYKTMSLGEVAKDVIGIAYKNLLGGIFRRAPEPLPSPEESPLPVPTKEAPMRIRCRLYDGKRDGLTLSVAPGGRLAVVTDNLDRVMLVDTHQAIILRVWKGYRDAQCAFVPVKEKSVRGIKTHKRKALFLVIYAPRMGCLDIWALQNGPKVAAFNVSKSGQLMYNNHSPLGSGGSSGSGNSSSQSRKSLAINHCLFLDPSDGSLKEIHIPFHYALSETSSQTSRDIHMLRRLRNQLRTINHGQAKDEALQEIGELASELQTLEVRQQCLEMLLKSKKLQPQVFQSIINAFIKKPLSESTGSEEFVNQIENYKRLTDLYLALSQANQREDNEPPVEYLELSDADLVTINKLVLLLDDGTEKDKPAATREVSFKLQAEHKTEEFVDYLSIFNIDSPDGISLLPEKSDKFGAVSIDLFSQFFAQGLCFGQFKQWINQACLPSRDLLKLIIWFWLEKPFKYNNCDEVVEDMSRIAAMVQTICDLAGEHIHDYAYNAISPWWQEVRELLLESKQFSGLLVAIVCKTVATNLWRNRKEGSCDESSQNEDDERWERISHDEAQWGLLTGKLEDVAVLGAILSKPLICRDPVGPEMSYEPPDCSLKSIVSSGKGIVTELTAKWLISAQLHPSKVLEISPPENELDDESKVKIKDEPTKESVDEDAESEEDLEMAKEVYAASKEAHEPILERLALLRAHFPFSLESGVLLSLMSWQYMVQWSKQLSSLDHLKAALLCLNQFRTPDWALKHGICCMLWNATLKFPLQAAAKLIQKVGRLPVDKMCQQDLEMSAGKVPEFLELSLEFLQHFTASMEHDKRELHFEQSLSEGALPLQFLALQQHHAMPQLLRLQTELCSVLHFVSFFQLRIPKPLTTLFDSMSNKALLADINKELPYVLPAPDLVLQQQRTEFLCRLVTATMDLIREDLEQLYILDHVFYMGKICALADSWEVDKLPILRRQVVELYAFGYDAEAQVLLQDISDDEELGRLLLEIAGRRLNLYAQSSQSTFLKIASVGHQLLAYLDNLKEPMTENNIQIAATKPDEIDVAALDRLLSHAYKYLCRRESKQLPIIGQMYNAVRILQN