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RSc1354

Gene
RSc1354
Protein
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Organism
Ralstonia solanacearum (strain GMI1000)
Length
165 amino acids
Function
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
Similarity
Belongs to the class II aldolase/RraA-like family.
Mass
17.56 kDa
Sequence
MMIPVTDLCDAHEDQLASGAVRVLAPVFRSFGARAAFAGPAATLKVFEDNGLVRAMLEQPGEGRVLVVDGGGSLRCALVGGNLAKLAEDNGWEGVLVNGCVRDTRELAACNVGVHALAAHPRKSFKKNQGERDIGVQMPGAYIHPGEWIYGDEDGVLVSRERLHD