Protein
Putative endo-alpha-N-acetylgalactosaminidase
Organism
Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235)
Function
Probably involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins.
Similarity
Belongs to the glycosyl hydrolase 101 family. A subfamily.
Sequence
MPFRGRRRQSALRGLSLAATFCLAAGSSGISGALFATPAQADPLPTAAGLSINSANLTVEVSADFPQALSYTETSSAKHLSGARTLASSITINGTDQPVKVSSQKADAQTVNYLITPNNLAGVSLDAQLRVEGMTLTFKISKIKDTAENRVNNLQIKNQDLVTVSSQEPGATVASAVVSVDRAVSGDTITNLSSTTALDPTAKRSMLAIAATDQLAAGFETNSLYDSGNTIGPSDQGKFWRQALADGTGADGKPAVKMAVSSGAWLYRSAGSDQTEELPWSKVVISGDANADGKVDWQDGAIAYRSIESKPAGGDDVKNRVVTHIPFNFASQATHPFLRTLDDVKHIALATDGLGQMALEKGYTSEGHDSANSDFGGNFNERAGGLTDFNAMLSGGSAYGATFGVHINNTEAYPEANSFSNDFVDPTKKGWNWLDQSFYIDQQRDILSGSQQQRIDQLRSEAGPNLTMAYVDVYYESGWKSYRLQKGLKDAGFSVASEFATAMPANNTWSHWANDEKHGGSNNIKAGTQILRFVDNSQRDIWNPDPLLGTSHIVEWEGWTNQNDYNAFLKNIWGNNLPVKFLQQQQITSWKSRSVDLTGGLKVTGTSLADRVISQQGVPVLKGSNYLLPWSAAPVSFGSGAVNDTTQNKLYHYSADGGTSTWQLTPQFATASSLQIYKLTDYGRELIGSVPVVNGSVTLTAEANQAYVLVADASVTTVPADPSYGAGSKVKDPGFNSAGLKDWNATGGAAVERTAQGLLVAKLGQGSSAISQTLGSLDPGSYSIGAWVEIEPTTLTVTPAGGAPISVTVDQSGAENFVASDEKRGTYFQRLRVLVDIANAGAPQLSISAPAGEAAVRIDDVRVVKANKVPTTGILSENFENTDQGWLPFIKGDAGGQTDPRTHIAKLNAPYTQKGWNGKTTSDVLDDTYSLHSHEENQGLVYRTSNYTLPLQAGRQYRVSFDYQASLANQYTWVSGYDSGKNPVQTASTAIPVATDTTRWSQTLSAGSCGPAWVGLQRTGSSGGAEFSMDNLLVEDLGPSAETPACASLSLTSGQDVIEQGQTNTFSASFSSSEAQSIAGLSVALDLPAGWTASAATPATAATLPAGGSLETQWKVQVPADADGDYTIKAKASYQTTVDPIGSRSATTETAVYTLPKPPTKDTYASDMQWIGTPSNGWGPVEKDQANGEQAQGDGPPLKLGGVTYPKGLGAHAASSIRYYVGSQCSAFTAVIGIDDFQKLKGQAVFSVLGDGNSLYTSPVMKGGAAAQTITVPLNGAKYVDLKVAISGANNGNAWSDWANAKFLCSAPVAPITLQPTLSVPTDSLQPGSAFTVRVDQLKSGSTAKAELHSDPIDLGSVQANNDGVASFQVTLAQDAPLGNHQIVVTGTDKNGLAATGTVDAQIKAANPNPGTGSNPGTGSNPGTDPGTGSAGGNSSGGGANGSGANGTYVNGSGGSFGNGAGMDAKTGSNSASSLAETGFSGLVLPLGIGLMLLLIGAAAIIVRRHRHS