Protein
Exosome complex component RRP45B
Organism
Arabidopsis thaliana
Function
Probable 3'->5' exoribonuclease involved in the regulation of cuticular wax biosynthesis by controlling the expression of CER3. May act by degrading a specific mRNA species encoding a negative regulator of CER3 transcription. Can perform exosomal functions and complement the yeast rrp45 null mutant.
Similarity
Belongs to the RNase PH family.
Sequence
MEGRLANMWRLTVNESKFVETALQSELRVDGRGLYDYRKLTIKFGKEYGSSEVQLGQTHVMGFVTAQLVQPYKDRPNEGSLSIFTEFSPMADPSFEPGRPGESAVELGRIIDRGLRESRAVDTESLCVLAGKMVWSVRIDLHILDNGGNLVDAANIAALAALMTFRRPDCTVGGENGQEVIIHPLEEREPLPLIIHHLPIAFTFGFFNKGNIVVMDPTYVEEAVMCGRMTVTVNANGDICAIQKPGEEGVNQSVILHCLRLASSRAAATTKIIREEVEAYNCERSLQKVKRHPTLAKSEVSGPTVAVKEEHRKSSDQERAAEISREHVERLKLSTEEVRSSKEEEAANFKGGPSNWDPYSEAMDVDSLKVSLASRGDPVTKSSSTKKMNGSGNAQKVGVEISVEEVTGELGKKDTKHKDGEMTLKDAVKPKKKRKNKS