About Products Protein Database Contact

RPL13A

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Picea mariana
Length
206 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.574 kDa
Sequence
MVSGSGICAKEVVVDARHHMLGRLASILAKELLHGQRVVVVRCEEICMSGGLVRQKMKYLRFLRKRMNTKPSHGPIHFRAPSRILWRTIRGMIPHKTKRGAAALATLRAFEGVPPPYDRKKRMVIPDALKVLRLQPGHKYCLLGRLSKEVGWHHFDTITELEEKRKAKAQVSYERRKQLAKLRSKAVELAEKQLAPEMELLASLKY

Gene
RpL13A
Protein
60S ribosomal protein L13a
Organism
Drosophila melanogaster
Length
205 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.647 kDa
Sequence
MTGLTNRTVVIDGRGHLLGRLASVVAKYLLQGGKVAVVRCEELNLSGHFYRNKIKFLAYLRKRCNVNPARGPFHFRAPSRIFYKAVRGMIPHKTKRGQAALARLRVFDGIPSPYDKRRRVVVPIAMRVLTLRSDRKYCQVGRLSHEVGWHYQDVIKSLERKRKAKLRVTLKHNRELKKLTVKARENIAKAAEPFNKIIKSYGYEV

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Lupinus luteus
Length
205 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.511 kDa
Sequence
MVSGSGIAAKRVVVDARHHMLGRLASIVAKELLNGQKVVIVRSEEICISGGLVRQKMKYLRFLRKRMNTKPSHGPIHCAPSKIFWRTVRGMIPHKTKRGEHALARLKVYEGIPPPFDKQKRLVVPDALKVLRLQKGHKYCLLGQLSSEVGWNYYDTIKELEKKRKERSQVVYERKKQLNKLRVKAEQVAQEKLGSQLDILAPVKY

Gene
RpL13A
Protein
60S ribosomal protein L13a
Organism
Choristoneura parallela
Length
204 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.348 kDa
Sequence
MTGFSNKAIVIDGRGHLLGRLAAVIAKVLLEGNKVVVVRCEQLNISGNFFRNKLKFMSFLRKRCNVNPARGPFHFRAPSKILWKTVRGMIPHKTERGKDALRRLRSYDGCPPPYDNRRRVVVPAALRVFCLKPGRKYCHVGRLSHEVGWKYREVVRKLEDKRKFKAVHKVAYERKLKKITKDAGAKVSKATAPFTAVIQSYGYN

Gene
RpL13A
Protein
60S ribosomal protein L13a
Organism
Spodoptera frugiperda
Length
204 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.367 kDa
Sequence
MTGFSNKAIVIDGRGHLLGRLAAVIAKVLLEGNKVVVVRCEQINISGNFFRNKLKFMSFLRKRCNVNPARGPFHFRAPSKILWKTVRGMIPHKTERGKSALRRLRAYDGCPPPYDNRRRVVVPAALRVFCLKPGRKYCHVGRLSHEVGWKYRDVVRKLENKRKVKSVKLMAYEKKLKRITKESGEKVAKTTAPFTAVIQSYGYN

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Bos taurus
Length
203 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (By similarity).
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.523 kDa
Sequence
MAEGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNIEKKIGKFTEVLKTHGFLV

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Canis lupus familiaris
Length
203 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (By similarity).
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.499 kDa
Sequence
MAEGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLNYLAFLRKRMNTNPSRGPYDFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLV

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Homo sapiens
Length
203 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.577 kDa
Sequence
MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLV

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Macaca fascicularis
Length
203 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (By similarity).
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.606 kDa
Sequence
MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTTTLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTQVLKTHGLLV

Gene
Rpl13a
Protein
60S ribosomal protein L13a
Organism
Mus musculus
Length
203 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions (By similarity). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex.
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.464 kDa
Sequence
MAEGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKMHYRKKKQILRLRKQAEKNVEKKICKFTEVLKTNGLLV

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Pongo abelii
Length
203 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (By similarity).
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.518 kDa
Sequence
MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTSPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLVRLRKQAEKNVEKKIDKYTEVLKTHGLLV

Gene
Rpl13a
Protein
60S ribosomal protein L13a
Organism
Rattus norvegicus
Length
203 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (By similarity).
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
23.476 kDa
Sequence
MAEGQVLVLDGRSHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLLRLRKQAEKNVEKKICKFTEVLKTNGLLV

Gene
RPL13A
Protein
60S ribosomal protein L13-A
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
199 amino acids
Function
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Similarity
Belongs to the eukaryotic ribosomal protein eL13 family.
Mass
22.554 kDa
Sequence
MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAAKIAPRPLDLLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRNGKAPEAEQVLSAAATFPIAQPATDVEARAVQDNGESAFRTLRLARSEKKFRGIREKRAREKAEAEAEKKK

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Tetrahymena thermophila (strain SB210)
Length
198 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
22.593 kDa
Sequence
MFDKLVVIDAKGHLLGRLASYVAKELLSGQRIVVVRTEAINISGSLFRNRVKFSEFLNKWMNHNPRRGVQHFRAPSRIFWRAVRGMLPHKTPKGAAALERLKIFEGIPTPYDRVKKQVVVDALKVQRLRNSRPVCKLGDLSASVGWGKQTLIEKLEEKRRARAKTYHDKKVKQADARKKELAAPALKAIKDKLAQFGY

Gene
rpl13a
Protein
60S ribosomal protein L13a
Organism
Salmo trutta
Length
189 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
21.681 kDa
Fragment
single
Sequence
LLGRLAAIVANEVLLGHKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVFDGVPPPYDKRKRMVVPAALKIVRLKPTRKFALLGRLAHEVGWKYQAITATLEEKRKEKAKIRYAKKKTVTKLSKLAEKNVESTISKYTAVLKQYGVLV

Gene
rpl13a
Protein
60S ribosomal protein L13a
Organism
Dictyostelium discoideum
Length
187 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
21.164 kDa
Sequence
MFQKKAIVIDGKGHLLGRLASVVAKSLLSGQKIVVVRCEELNISGPLSRNKLKWADFLNLTMNTNHARGHRHGRSPSKIFWRAVRGMLPHKTPRGQAALDNMKVFEGVPAPYDKVKRVVVPSALRVVKLNTTRKYTVLSRLSQEVGWKYRAVVAKLEVQRKQRSSTYYRKAALVKAYRTQALKKFSA

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Sus scrofa
Length
137 amino acids
Function
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (By similarity).
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
15.674 kDa
Fragment
single
Sequence
QVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKLTGKFXYLGRL

Gene
RPL13A
Protein
60S ribosomal protein L13a
Organism
Spinacia oleracea
Length
15 amino acids
Similarity
Belongs to the universal ribosomal protein uL13 family.
Mass
1.489 kDa
Fragment
single
Sequence
VSGSGIMAKRVVVDA