Protein
Ribonuclease Z, mitochondrial
Organism
Drosophila melanogaster
Function
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity of nuclear and mitochondrial pre-tRNA. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. May participate in tRNA processing in the developing embryo.
Similarity
Belongs to the RNase Z family.
Sequence
MYLVKSAGSPIYRTLRTLTTSNLMAATIASAKDPLTGPRYEREPNVLRKKLASVVPGTVNLQVLGSGANGAPAAVYLFTDQARYLFNCGEGTQRLAHEHKTRLSRLEQIFLTQNTWASCGGLPGLTLTIQDAGVRDIGLHGPPHLGSMLQSMRRFVVLKNLQVRPNDCSEGACFEDSILKVDSLPLINSEDPTKSVINYICQLKPRAGALNLVKCVEQGVPPGPLLGQLKNGNDITLPDGKVVRSVDVTEASETALSFVFLDVPSENYLPALLTHGKRLKKLGEEKLTEVALVVHFTPYHISSRQVYKDFVVESFSSEAQHIYLSSPLNQFSGYAAAHRIQHQLHQLAPQVFPLLGEQLSCQSQTLSLNLKKTKLDEADSEDKANAKANETEEQGVVAMTNYHLRPRKGLDRTLESKLTPEEYVKETHAVPGFLELLAKFKEEYSFPDNSADSYPKIIFLGTGSCIPNKTRNVSSILIRTAIDAYVLLDCGEGTYGQIVRLYGHEKGQLILRQLQAIYVSHLHADHHIGLIGLLRERRQLKPRADPLILLAPRQIEPWLEFYNRQIETVEDAYTLVGNGELLASPLSGEQVERLGITSISTCLVRHCPNSFGISLTLAAKHNSEPVKITYSGDTMPCQDLIDLGRDSTVLIHEATMEDDLEEEARLKTHSTVSQAIQQGRNMNARHTILTHFSQRYAKCPRLPSDEDMQRVAIAFDNMEVTIEDLQHYHKLYPALFAMYAEYTEELEQRAVKRELKQERKRKLAET