rne

Ribonuclease E

1061 amino acids

Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Can also process other RNA species, such as RNAI, a molecule that controls the replication of ColE1 plasmid, and the cell division inhibitor DicF-RNA. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process. Required to initiate rRNA degradation during both starvation and quality control; acts after RNase PH (rph) exonucleolytically digests the 3'-end of the 16S rRNA (PubMed:27298395). Degradation of 16S rRNA leads to 23S rRNA degradation (PubMed:27298395).

Belongs to the RNase E/G family. RNase E subfamily.

118.197 kDa

MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPAAPAQPGLLSRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAVVAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRSRRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQVEEQREQEEVHVQPMVTEVPVAAAIEPVVSAPVVEEVAGVVEAPVQVAEPQPEVVETTHPEVIAAAVTEQPQVITESDVAVAQEVAEQAEPVVEPQEETADIEEVVETAEVVVAEPEVVAQPAAPVVAEVAAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQRPTFAFEGKGAAGGHTATHHASAAPARPQPVE

rne

Ribonuclease E

1037 amino acids

Endoribonuclease that plays a central role in RNA processing and decay. Plays a major role in pre-16S rRNA maturation, probably generating the mature 5'-end, and a minor role in pre-5S and pre-23S rRNA maturation.

Belongs to the RNase E/G family.

112.762 kDa

MAEDAHTEDLSTQTPQQEGLPERLRVHSLARVLGTTSRRVLDALAEFDGRQRSAHSTVDKADAERVRAALTESPAAETPPEEAPAAETPVADLVVVQAEQVEVVTVSEAGPAEPAEPAEPEAPAAEAEAEAETEVADEAETPEPTFRGAVLVGDEPESRLILEHANIPPARETQTERPDYLPLFVAPQPVSFEPAVVDDEDEDDDTETGAESDFDSGADSDSDDDQADRPRRRRRGRRGRGRGRGEQNDDATSDADTDSTEDQTDGDEQESGEDSDDSGDEDSTTTEGGTRRRRRRRRRKSGSGDSDDAVSPDDPPNTVVHERAPRTERSDKSDDSEIQGISGSTRLEAKRQRRRDGRDAGRRRPPILSEAEFLARREAVERTMIVRDKVRTEPPHEGARYTQIAVLEDGVVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLGGQNRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGVKEEDIRSDVERLQKRWSEIEAKAAEVTEKKAGAAVALYEEPDVLVKVIRDLFNEDFSSLIVSGDEAWNTINSYVEAVAPDLMPRLTKYEPAGPDAPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTACTHCGGRGIVLHGDPIDSASSNGGRKSDSSGGGGSGGGRRGKRGKKGAARTEEVHVAKVPDHTPGEHPMFKAMAAANGKHEGDEDHEDHEDHETAEDTTAAEVRDDTRDEHDADERAHVVTAAVGAAGDEDLDDSDEDSDLDSDEESDDESDEDEIELDDDEDELDEDIEVIGDSDDSDDSDDSDEDDDSDDSDDDSDEDEDSDSDEDEEPVREVYEPPVTAPRARVRRRAAARPAGPPSHD

RNE

Ribonuclease E/G-like protein, chloroplastic

1001 amino acids

Involved in intercistronic processing of primary transcripts from chloroplast operons. The endonucleolytic activity of the enzyme depends on the number of phosphates at the 5' end, is inhibited by structured RNA, and preferentially cleaves A/U-rich sequences.

Belongs to the RNase E/G family.

111.552 kDa

MDVTEVPWRRLPQFSVSSRASWLVSSGFPLSSYMFSHVERGKTFRLTLCFGVSRLRPRSAIPLRFLLSVFSEQPPSRLKGLCEVVWIVEADLAANEHLYVTGDPSTLGSWEPDCAISMYPTENDNEWEAKVKIASGVNFRYNYLLKAGYGSSSDVIWRPGPQFSLSVPSSVNQDRKIIIRDSWMSMSISSKSQESYGWGSWIDDAYLFPNCVTPAQSEDECTSADSAIEVPRTHLNDKQVGAESFLCDELAAFSSENSNLSALFSDNYQPIEEPWLIQESITLQHERNMQTDSEQDVESCDDNENNLNTDEQNHQLTETLLPDGGFFQSESIATTILINSSICTVQRIAVLEGGKLVELLLEPVKTNVQCDSVYLGVITKFVPHMGGAFVNIGSARHSFMDIKSNREPFIFPPFCDGSKKQAADGSPILSMNDIPAPHEIEHASYDFEASSLLDIDSNDPGESFHDDDDEHENDEYHVSDHLAGLVNGTVVNHGAVEVGSENGHIPMERGHSADSLDSNASVAKASKVMSSKDNKWIQVRKGTKIIVQVVKEGLGTKGPTLTAYPKLRSRFWVLLTRCKRIGVSKKISGVERTRLKVIAKTLQPQGFGLTVRTVAAGHSLEELQKDLDGLLLTWKNITDEAKSAALAADEGVEGAIPALLHRAMGQTLSVVQDYFNDKVEKMVVDSPRTYHEVTHYLQDMAPDLCNRVELHDKGIPLFDLYEIEEEIEGILSKRVPLSNGGSLVIEQTEALVSIDVNGGHGMFGQGNSQEKAILEVNLAAARQIAREIRLRDIGGIIVVDFIDMADESNKRLVYEEVKKAVERDRSLVKVSELSRHGLMEITRKRVRPSVTFMISEPCSCCHATGRVEALETTFSKIEQEICRQLAKMEKRGDLENPKSWPRFILRVDSHMSSFLTTGKRTRLAILSSSLKVWILLKVARHFTRGTFEVKPFMDEKTVNERQHQVAISLLKKADAIADSSGKKKLTLIPIKKEKTSGKQRR

rne

Ribonuclease E

968 amino acids

Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

Belongs to the RNase E/G family. RNase E subfamily.

112.656 kDa

MKRMLINATQQEELRVALVDGQRLYDLDIESSRSEQKKSNIYKGKITRIEPSLEAVFIDYGMEKHGFLPLKEISKNYFPENYNCDVRLNIKDILREGQELIVQINKEERGTKGAALTTFITLAGSYLVLMPNNPKIAGISRRVEGSDRIELKELLSSLKIPEKMGLIIRTAGVGKSIKSLQWDLSLRLKHWNAIKKASKKKSAPFLIYQESNVIVRAFRDYLRQDIGEILIDNPKILDIAREHITALGRPDFINKIKLYTGEIPLFSYYQIESQIDSAFQRKVRLPSGGSIMVDTTEALTAIDINSSRSTRGADIETTAFNTNLEAVEEISRQLRLRDLGGLIVIDFIDMTTISHQKIIENKLREIVREDRARIQIGHISKFGLLEMSRQRLSSSLGESSHHICPRCTGTGTIRDNESLSLSILRLIEEEALKENTYEVHAIVPIEIACYLLNEKREAVYAIEKRQAGGKTIIVPNKNMKTPHYLVSRIRKGEQIRSMSYCLSNVRKNKIFNNIKKEIVDKKHKLNSTLTNISLSDDSFDKQKEEKEKFLRKKNYNNSIINALFNNKNLFFKFIVWIKNSFLKKHIFVKNESFKRNIFQNKKNILFAKKEEFNSIEEIHKKDNQVSSIDNNKKKQLLNKVKKNNNHQYSHVFDNNTKYTSLKKIDFQKNTIDFELNSLNFLKKNNFYIFSKYNFLYTKKYAKNKFKDFENIKSQNDMICYESFQKDLENNTSFKKKLLYNIIFNNCYPNNILVNINSTIFQIYKNSEFFKFFPIKISILMTPLNIFSLELILEPSSKKCSSFKENQVKKRLRINNYKKLNSSFIHKKNNFVKNSVLWPKKFTTEEIKINHLYKKNKKNTKSYFFETSFKYKTVTKNISKLKVKLTSKKNDYLISNQKKLFLNKTLKKENTKNKSSAPITKIFSDVFLSKNQKIMNSSIFLKKSNKKIKNSAGAHSATNFSTSPVKKSE

rne

Ribonuclease E

935 amino acids

Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

Belongs to the RNase E/G family. RNase E subfamily.

106.584 kDa

MKRMLINATQKEELRVALVDGQRLFDLDIESPGHEQKKANIYKGKITRVEPSLEAAFVDYGAERHGFLPLKEIAREYFPDDYVFQGRPNIRDILVEGQEVIVQVNKEERGNKGAALTTFVSLAGSYLVLMPNNPRAGGISRRIEGDERTELKEALSSLDVPDGVGLIVRTAGVGKSPEELQWDLKVLLHHWEAIKQASQSRPAPFLIHQESDVIVRAIRDYLRRDIGEILIDSPKIFEKAKEHIKLVRPDFINRVKLYQGEVPLFSHYQIESQIESAFQREVRLPSGGSIVIDVTEALTAIDINSARSTRGGDIEETALNTNLEAADEIARQLRLRDLGGLVVIDFIDMTPIRHQREVENRIRDAVRPDRARIQISRISRFGLLEMSRQRLSPSLGESSHHICPRCQGTGKVRDNESLSLSILRLLEEEALKENTKQVHTIVPVQIASYLLNEKRKAISNIEKRHNVDIIVAPNEAMETPHFSVFRLRDGEEVNELSYNLAKIHCAQDENTEESLLSRNVETTAVIEQPAVESAVVALSISEAAPTPVERKSNEPSLLAKIIAKIKGLFATKSEENKPKNNRTSRNPNRNQRRSQDRRSSRRPRSENNETERTEEQVRNVRERNQRRPRRNLVEESIAESAVNSTPVFEAKEERTEPVTQRRQRRDLRKRVRVEDNETVVENNFSTTEKMPEVDVITVQNNDEKPVHQNQRSERQERQRRTPRHLRAANNQRRRRDQEPKSPMPLFAAVVSPELASGKAWIDYSTVNLPKENHFLSVDELLEQEKTKKGFITPAMGIVVEEKSPDVKPALDFITQPANESVQKKVQESLDRLSSYKPQEVVESIDPAINVDEPETLEKVSKFVRTYEFNGRLGTISSVPHTKAEMTLAKANDEMPEDFPIRAWQDSRYYFYGKGAAGHHCAISHVYSEPTRTKSE

rne

Ribonuclease E

902 amino acids

Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

Belongs to the RNase E/G family. RNase E subfamily.

104.007 kDa

MKRMLINATQQEELRVALVDGQRLYDLDIEHSGSEQKKSNIYKGKITRIEPSLEAAFVDYGEEKNGFLPLKEISKNYFPENHIETLGFNIKNVLQEGQEVIVQISKEERGTKGAALTTFISLAGSYLVLMPNSPKSGGISRRIEGNDRIALKELLTLLELPEEMSLIIRTAGAGKSIESLRWDLSLRLQHWKTIQIIAKSRTAPFLIHQESNIIVRAFRDYLRQDIGEILIDNPKILDLARKHITFLGRPDFVNKIKLYSGEVPLFSYFQIETQINSAFQRKVRLPSGGSIMVDSTEALTAIDINSSRSTSGTDIASTAFNTNLEAVDEISRQLRLRDLGGLIVIDFIDMSAISHQRAIENRLREIARDDRARIQIGQISRFGLLEMSRQRLSSSLGESSHHICPRCTGTGTIRDNESLSLSILRLIEEEALKENTYEVRAIVPVEIACYLLNEKRDAVHAIEKRQAGGKTIIVPSKKMKTPHYSVSRIRKSESKNYTRYGLSNIRQSKITSFLKKNLLKKKQKEILDVANFNFYDNCYNKIQEAQENILKKNNYNNILLKVLSNNRNFIFKMITWFKNSFFIKNMLITSDIFKKNTLKNTNNIFFKKKYSSLNKKNNNQKKRVILSKLFEANIENIPLKNKKLDTSSANYLYDNIERKKNITKKNDLIQKNIHENSYLKHVLMNRYNVINIINNNYIFYKIFNRTKIFKNQNTNNSFLKFSSVTSPIFIFSSVFSLELALGKVWIKYPIAILDETKKQKKLNRKQILHISSISETNTIVNKNNYSGIKKIKHETYSFKKYVKNNIQNQEVTQSQLIKRTKKRNVFILDKKNFLYKRTCNRKNKIHQSSAPITKISKQSDLNKKEKEFHYNLSMMKSSLRGKNSAGVHSATNFSNSPVSKLK

rne

Ribonuclease E/G-like protein

674 amino acids

Belongs to the RNase E/G family.

74.944 kDa

MPKQIVIAEKHQVAAVFWKDQIQELVVSTGSQQVGDIYLGLVDNILPSIDAAFINIGDTEKNGFIHVSDLGPVRLRRTAGSISELLSPQQRVLVQVMKEPTGNKGPRLTGNISMPGRYMVLMPYGRGVNLSRRINREEERSRLRALAVLIKPPGMGLLVRTEAEDVPEDAIIEDLENLQKQWELVQQQAMTRSAPMLLDRDDDFIKRVLRDMYSSEVNRIVVDTPAGMKRIKQQLMNWDQGRLPEGVLIDCHRESLSILEYFRVNATIREALKPRVDLPSGGYIIIEPTEALTVIDVNSGSFTHSANSRETVLWTNYEAATEIARQLKLRNIGGVIIIDFIDMDSHKDQLQLLEHFNRCLETDKARPQIAQLTELGLVELTRKRQGQNLYELFGQPCPECGGLGHLVELPGEKGFVSLSPTAVNSSIPPRLVEKPILSPPVAKVNDLPKKEEAKISSPLDLLFHPNYQEQGDRDSNRRRRRRRGSEFSEKENIKSVGISRSKGPSPSPTKEKVTGTAPPRRERPSRRVEKTLVPVDVAMTTLEQDIYARMGISPLIKTEYADQDPRSFMVSVVTAGAALEGNTNGSGSLVNAVITTVDNGDNGDNVPSDGLTIVSEVTAPTPVIEQPREETVEPEQVVLPQLDDETPAAPVAEESAPIETKKRPGRRRRRSSAE

rne

Ribonuclease E/G-like protein

511 amino acids

Belongs to the RNase E/G family.

58.795 kDa

MTNTIVISCLHNIAAILYCGQIQKLVVANAHYQVSDIYLGTVDKIFSGINAAFVDLGKNEYSGFIHISDTGPLKKKYYINNITNILTIRQKILVQIIKEPTLNKGPRLTANITLSGRYIVLMPFSQAICISRKIYDEDERHYLKALAILIKPPTMGLLFRPSAIGIDEEIILSELTNLKEQWYFIQKSAINNCAPVLLYKDEDIVKKVIRDFYDNNTKNIVIDSNLGLKQLNYYINTWQCNFSSTIPSLQLYSSNKCILDTFRINQAISRALIPKVDLILGGYMFIETLEAFTIIDVNSGSFNNSTSARETVLKTNCSAATEIAYQLKIRNIAGVIIIDFIDMESQRDQLQLLEHFDKELSLDDAKPQIVQLSELGLVELTRRRKGKSLYELVSNDSNYFHFFIQLEQLDSIKPSSYKSKRLSSSVKSWLFSEIDMINRVFFKKSNLYRLSNFYYARNLYIIYSDFTVNKNIQLAARYKLMYSLQNIQILPSTWYFNFLDIHTNNITNYLS

rne

Ribonuclease E/G-like protein

509 amino acids

Belongs to the RNase E/G family.

58.425 kDa

MTNTIVISCLHNMAAILYCGQIQKLVVANAHYQVSDIYLGCVDKIFSGINAAFINLGKNEYSGFIHISDTGPLKKKYYVNNITNILTIRQKILVQIIKEPTLNKGPRLTANITLSGRYIVLMPFSQSICISRKIYDEDERHYLKSLAILIKPATMGLLFRPSAVGVDEEIILSELKNLKEQWNFVQKSAINSYSPVLLYKDEDIVKKVIRDFYNNNTNNIVIDSNLGLKQLNYYIHTWHCNNSSTVPKIKLYSNNQCILDAFGINQAISRALIPKVDLILGGYMFIETLEAFTIIDVNSGSFNNSTSARETVLKTNCSAATEIAYQLQIRNITGVIIIDFIDMESQRDQLQLLEHFNKELSLDDAKPQIVQLSELGLVELTRRRQGKSLYELISSDSNYFYFFTQSERSQSLKRFDDRQQKQQIFNKSWLSAEINTINKVFFQKSNLCRPANFYLIRNLYIVKSSITYKQNYLLTHRSKLIYSKEYSKVLPSSYYLASLNKNSNQEFLS

rne

Ribonuclease E/G-like protein

429 amino acids

Belongs to the RNase E/G family.

50.078 kDa

MSFNIIILKELGFSLVFSQSKCEYIIFQKEQCGLNDIYFGFIPRQSIYPTLNAAFVTLDSERNQGFIPFTLLIKKSNQQFVIPNSVFLIQVIKEPTINKPATLTSHIFLNSFNLNLQFSGIDCKYLNLYPNIKFLHICLITLLIPSGLDINFDHSMKDILYLDLIGQSKILYYSFSNLFTKLLRIKKMPQFIFRNSNFFLPILNKLSLSSINDFFVSSYQRAVYLRHFLITHYFTIKQTDYRILFYPTAYKSMQLYYLDMLFYRSLKPIVYTLYGIFIVICKTEALISIDVNSGSHSSRVSQNLSLHTNLIASKSIIKEIKLRNLAGVIVIDFVDMIHQKDQIHLLAFFRYLLNINSVMITLIQLSDIGLLELTRKRQDQSIYDVFQIGNISKSSFLYDRILSLNKNLFKTNLLINYTLFSNVKLIYNY

rne

Putative ribonuclease E

410 amino acids

Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs (By similarity).

Belongs to the RNase E/G family. RNase E subfamily.

47.312 kDa

MRRMLINAIEIKKLRIALIDGQQLYDLNVENIDKKQRKSNIYKGKIVRIEPSLEAAFVDYGEKKNGFLPLKEISRNYFPNNCSNYRHLHIKNILKEGQECIVQIDKEERGTKGALLTTFISLAGNYLVLMPNCPHLEGISRKIEGIDRFHLKKIISMLMVPENMGIIIRTSGVGRSIETLQLDLNFRVKNWYTIKKSAEINTAPCLIHKESNIVIRTLRDYLKKDIQEIIVDNPEILELARDYMFNMNCSYFEKKIKLYTGSDPLFSYYKIESQINALLRRIVKLPSGGSIIIDYTEALTAIDINSSQSTKGVNIEETAFNTNYEAVREIARQLRLRDLGGLIVIDFIDMSVLKHQKMIELHLHQVLQKDRARVQVGSISQFGLLEMSRQCLGSPLKKINHNYLFEMQKC

rne

Ribonuclease E/G-like protein

375 amino acids

Belongs to the RNase E/G family.

42.619 kDa

MLVVGNRIVDVSRHTSIGTIVIATVDKLAPGLGIAFVSWTHGQGKGGLPSTKKHYGILPLRSWRGRGPLDFATTHELTGENLILQHGDFVLVQIVQDGNHAKVHLVSGHIALTTSRLVVWPGLSSKDWIFSHQIGQKINNYLHVRKLVSYMRRDQILCTGPQRWMKEQYALEHQWENFVLEFIEQPTGISYLTSMTEKFVSPVCAEWFQHPLSVWIIGCNLQIRESMTKWMITHVPHKSRHIEITTLDAWKNWYNLHRAAIVQPQIPLRSGGTMIIEFTEIGWSFDINSGIGLEIGSKTCANEEAIYAIAQQILLRSMHGFILIDFIGDIDLEKLRVNLIQFTSLLEQDSYHIRIISISADGLVCVIRHRRSKLI