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RIPK

Gene
RIPK
Protein
Serine/threonine-protein kinase RIPK
Organism
Arabidopsis thaliana
Length
462 amino acids
Function
Serine/threonine-protein kinase involved in disease resistance. During Pseudomonas syringae infection, and in response to the bacterial effectors AvrB and AvrRpm1, RIPK phosphorylates the host target RIN4, which subsequently activates RPM1-dependent effector-triggered immunity (ETI) (PubMed:21320696, PubMed:25625821). Seems to act as negative regulator of plant basal defense responses and may play a role in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) (PubMed:21320696). Required for the bacterial XopAC/AvrAC effector-triggered immunity against Xanthomonas campestris (PubMed:23951354).
Similarity
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Mass
51.701 kDa
Sequence
MAVKKKVSWRSLIVGCLGDPETLMASSKKPKRKNDVIKKQSSFQRLSILDMSNPSSNTLSEDLSISLAGSDLHVFTLAELKVITQSFSSTNFLGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLEGLQGHREWLTEVMFLGQLKHKNLVKLIGYCCEEEHRTLVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAENPVIYRDFKASNILLDSDYTAKLSDFGLAKDGPEGDDTHVSTRVMGTQGYAAPEYIMTGHLTARSDVYSFGVVLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRIMDPRLEGQYSETGARKAATLAYQCLSHRPKNRPCMSAVVSILNDLKDYNDIPMGTFTYTVPNTPDNKEDDGRVGNKPRKSSHHHHHQQQQSNHPRSSPSPTTKSPSPTAKSPRNSTENHRRTLRNGVNSPLRSEAGGERY