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RILPL1

Gene
rilpl1
Protein
RILP-like protein 1
Organism
Danio rerio
Length
406 amino acids
Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein (By similarity).
Similarity
Belongs to the RILPL family.
Mass
46.917 kDa
Sequence
MEEQQLGAALDKSAAELSVMDVYDIAAALGLELERVIERTGAELLSRLVPRVVRVLELLEVLVSRSSSSPDTDELRLELDRLRLERLERLEKEKKHKKELELVEDVWRGEAQDLLCQISQLQEENKTLLNNLSIRESPLTEEDIQKQEGMTERERQVMKKLKEVVDKQRDEIRAKDRELTLKNDDVEALQQQMSRLMKINQDVRHRVSVVEAQGKSLIQQKVELEAAAQTQQQEVSSLRQEVSRLKEKLKEQSRSNEEEAQEPVGPPSPAQEALCDEDLSTVDLKDPNRPRFTLQELRDVLHERNELKAKVFMLQEEIAYYRSEEQEEENGPPLPDPSETLRTNPRSNFQPESGIKRLFSFFSRDRSVSQRRMMLNVEPVGDAVGSWTGKQEDVYTETAQEALQHM

Gene
Rilpl1
Protein
RILP-like protein 1
Organism
Mus musculus
Length
406 amino acids
Function
Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution (By similarity). Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia.
Similarity
Belongs to the RILPL family.
Mass
47.323 kDa
Sequence
MEEPLGSPPAALSALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCESIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRVERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLNHKDVGFSEEEFQKQEGMSERERQVMKRLKEVVDKQRDELRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEEAEIQPQPDGEESISDAEKAALDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEIEEENRIPQPPPITHPRTSPQPESGIKRLFSFFSRDKKRLANTQRPTHIHESFGQWAITQRDDGYTEQGQEALQHL

Gene
Rilpl1
Protein
RILP-like protein 1
Organism
Rattus norvegicus
Length
406 amino acids
Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution.
Similarity
Belongs to the RILPL family.
Mass
47.33 kDa
Sequence
MEEPLGSPPAALSALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRVERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLNHKDVGFSEEELQKHEGMSERERQVMKRLKEVVDKQRDEIRAKDRELVLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEEAEIPPQPDGEESISDAEKAALDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEIEEENRIPQPPPITHPRTSPQPESGIKRLFSFFSRDKRRLANTQRPTHIHESFGQWAITHRDDGYTEQGQEALQHL

Gene
RILPL1
Protein
RILP-like protein 1
Organism
Bos taurus
Length
403 amino acids
Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution (By similarity).
Similarity
Belongs to the RILPL family.
Mass
47.01 kDa
Sequence
MEEDRGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLIPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVSFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGELNQNGEEEPVAELGGEECVSEAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEIEEENQIPQPPPIAHPRMSPQPESGIKRLFSFFSRDKKRLANTQRNVRIHETFGQWANCHRDDGYTEQGQEALQHL

Gene
RILPL1
Protein
RILP-like protein 1
Organism
Homo sapiens
Length
403 amino acids
Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
Similarity
Belongs to the RILPL family.
Mass
47.108 kDa
Sequence
MEEERGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEPETEPVGEESISDAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIPQPPPIAHPRTSPQPESGIKRLFSFFSRDKKRLANTQRNVHIQESFGQWANTHRDDGYTEQGQEALQHL

Gene
rilpl1
Protein
RILP-like protein 1
Organism
Xenopus laevis
Length
394 amino acids
Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein (By similarity).
Similarity
Belongs to the RILPL family.
Mass
46.59 kDa
Sequence
MEGISALEKNVAELTVMDVYDIASAVGQEFERVIDQYGCEVIGRLMPKVVRVLEILEVLVSRNHINPEMEELRLELDRLRLERMDRIEKEKKHLKELELVEDVWRGEAQDLLNQISQLQEENKQLLTNLSHKDVNLTEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRARDRELVLKNEDVEALQQQQSRLIKINHDLRHRVTVVEAQGKALIEQKVELEAYLQTKEQEAASMRIEIGKLRDKLKGEHHTNGEEIKTETLNEECIFETEKFSLDLKDSNRPRFTLQELRDVLHERNELKAKVFMLQEELAYYKSEEAEEENKLPQSLPVINSKAPIPQESGIKRLFSFFSRDKKRMPMMQKNVHFQESFGEWTNYNRDDVYTEQGQEALQHM

Gene
rilpl1
Protein
RILP-like protein 1
Organism
Xenopus tropicalis
Length
394 amino acids
Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein (By similarity).
Similarity
Belongs to the RILPL family.
Mass
46.461 kDa
Sequence
MEGISALEKNVAELTVMDVYDIASAVGQEFERVIDQYGCEVIGRLMPKVVRVLEILEVLVSRNHINPEMEELRLELDRLRLERMDRIEKEKKHQKELELVEDVWRGEAQDLLNQIAQLQEENKQLVSNLSQKDINLTEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELVLKNEDVEALQQQQSRLMKINHDLRHRVTVVEAQGKALIEQKVELEAYLQTKEQEAASMRLEIGKLRDKLKGEQHTNGEEIKTETLNEESILETEKLSLDLKDSNRPRFTLQELRDVLHERNELKAKVFMLQEELAYYKSEEADEEHKLPQSSPVIDSKAPIPQESGIKRLFSFFSRDKKRMPMMQKNVHFQESFGQWTEYNRDDVYTEQGQEALQHM