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RGS7BP

Gene
RGS7BP
Protein
Regulator of G-protein signaling 7-binding protein
Organism
Bos taurus
Length
257 amino acids
Function
Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
Similarity
Belongs to the RGS7BP/RGS9BP family.
Mass
29.044 kDa
Sequence
MSSAPNGRKKRPSRSTRSSIFQISKPPLQTGDWERRGSGSESAHKSQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLREEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGSKSLDCKIEECAETPALEDSSPSPVDIQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLVSS

Gene
RGS7BP
Protein
Regulator of G-protein signaling 7-binding protein
Organism
Homo sapiens
Length
257 amino acids
Function
Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
Similarity
Belongs to the RGS7BP/RGS9BP family.
Mass
28.962 kDa
Sequence
MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS

Gene
Rgs7bp
Protein
Regulator of G-protein signaling 7-binding protein
Organism
Mus musculus
Length
257 amino acids
Function
Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
Similarity
Belongs to the RGS7BP/RGS9BP family.
Mass
29.023 kDa
Sequence
MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASGGAKNLDSKIEENAETPALEDSLSSPLESQQQCWQVATDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPMVRRRKRRFFGLCCLVSS

Gene
Rgs7bp
Protein
Regulator of G-protein signaling 7-binding protein
Organism
Rattus norvegicus
Length
257 amino acids
Function
Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
Similarity
Belongs to the RGS7BP/RGS9BP family.
Mass
28.966 kDa
Sequence
MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASGGAKSLDSKIEENAETPALEDSLSSPLDSQQQSWQVATDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPMVRRRKRRFFGLCCLVSS

Gene
rgs7bp
Protein
Regulator of G-protein signaling 7-binding protein
Organism
Xenopus laevis
Length
254 amino acids
Function
Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
Similarity
Belongs to the RGS7BP/RGS9BP family.
Mass
28.909 kDa
Sequence
MSSALNGRKNRPRDSQGSRFQISHKALPRDCERKGSADSALTPQRTLEHCKMLVQDFNTQVALFRELVISIGDVSVNCPSLRAEMHKIRTKGCEMALHAHQKLSAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSMCLLGSLQHQQKGKEPCVGPRIIDYKPEESSDIPILDDTSSSPTDMQQQCWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKKRFFGLCCLISS