Protein
Regulator of free ubiquitin chains 1
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Function
Inhibitor of the DOA4 deubiquitinase involved in the regulation of protein degradation by the proteasome and maintenance of a normal level of free ubiquitin.
Similarity
Belongs to the RFU1 family.
Sequence
MKSSSHLKQEALNYRFNSNVPLKLYLTTCISIVEEAQNSARCNNMERAYLLYIRYLDLCLNRLVHHSEVNTSVESLYKREYFQLLKLEVPAIMKITEELKIKIDARYKSLANNVATSTYVRSPAVMTTNPSDEINLPSSFDEQKFNQSISWFNHSSKHFSAQSDSNNEYPELPELNATSTSVTYTMPAL