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RAMAC

Gene
Ramac
Protein
RNA guanine-N7 methyltransferase activating subunit
Organism
Mus musculus
Length
119 amino acids
Function
Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. Binds RNA.
Similarity
Belongs to the RAM family.
Mass
14.556 kDa
Sequence
MSDTSEEIPNFEEMFASRFTKDDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNWLQDNRQFRGRDNRRGWPSDNRSNQWHGRSWGNNNYPQQRPEPYYQQQYTQYGHNQRPPYGYY
Protein
RNA guanine-N7 methyltransferase activating subunit: Ramac

Gene
RAMAC
Protein
RNA guanine-N7 methyltransferase activating subunit
Organism
Homo sapiens
Length
118 amino acids
Function
Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:22099306, PubMed:27422871). Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT (PubMed:27422871). Regulates RNMT expression by a post-transcriptional stabilizing mechanism (PubMed:22099306). Binds RNA (PubMed:22099306).
Similarity
Belongs to the RAM family.
Mass
14.381 kDa
Sequence
MTDTAEAVPKFEEMFASRFTENDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNRLQDNRQFRGRDNRWGWPSDNRSNQWHGRSWGNNYPQHRQEPYYPQQYGHYGYNQRPPYGYY
Protein
RNA guanine-N7 methyltransferase activating subunit: RAMAC

Gene
RAMAC
Protein
RNA guanine-N7 methyltransferase activating subunit
Organism
Pongo abelii
Length
118 amino acids
Function
Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. Binds RNA.
Similarity
Belongs to the RAM family.
Mass
14.367 kDa
Sequence
MTDTAEAVPNFEEMFASRFTENDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNRLQDNRQFRGRDNRWGWPSDNRSNQWHGRSWGNNYPQHRQEPYYPQQYGHYGYNQRPPYGYY
Protein
RNA guanine-N7 methyltransferase activating subunit: RAMAC

Gene
ramac
Protein
RNA guanine-N7 methyltransferase activating subunit
Organism
Xenopus tropicalis
Length
116 amino acids
Function
Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. Binds RNA.
Similarity
Belongs to the RAM family.
Mass
14.301 kDa
Sequence
MAEALGAQELYEKMFEQRFTANDKEYQEYLKREQDQPPIVEDWKMGNQRNTDRYRDNRHHRGWDGRQNWSSNSYNQSYGRGGWGNSYNQYRQDRHNYQQGHYTHNPSNQRFHSDRY
Protein
RNA guanine-N7 methyltransferase activating subunit: ramac