Protein
Envelope protein p54
Organism
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)
Function
Envelope protein involved, through its interaction with host dynein, in the intracellular microtubule-dependent transport of viral capsid toward viral factories. Seems to induce caspase-3 activation and apoptosis. Plays a role in virion morphogenesis by recruiting and transforming the host ER membranes into the precursors of the viral envelope.
Similarity
Belongs to the asfivirus envelope protein p54 family.
Sequence
MDSEFFQPVYPRHYGECLSPVSTPSFFSTHMYTILIAIVVLVIIIIVLIYLFSSRKKKAAAAIEEEDIQFINPYQDQQWVEVTPQPGTSKPAGATTASVGKPVTGRPATNRPVTDRPATNNPVTDRLVMATGGPAAVSAAASAAASAAASAAASAPAHPAEPYTTVTTQNTASQTMSAIENLRQRSTYTHKDLENSL