Protein
Viral histone-like protein
Organism
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)
Function
DNA-binding protein that plays a critical role in viral DNA replication and gene expression. Binds to both ssDNA and dsDNA with a binding site covering about 15 nucleotides. Displays DNA-supercoiling activity only when associated with the viral DNA topoisomerase 2.
Similarity
Belongs to the bacterial histone-like protein family.
Sequence
MSTKKKPTITKQELYSLVAADTQLNKALIERIFTSQQKIIQNALKHNQEVIIPPGIKFTVVTVKAKPARQGHNPATGEPIQIKAKPEHKAVKIRALKPVHDMLN