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Papst2

Gene
Papst2
Protein
Adenosine 3'-phospho 5'-phosphosulfate transporter 2
Organism
Drosophila melanogaster
Length
396 amino acids
Function
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Essential for viability. Involved in glycosaminoglycan synthesis and the subsequent signaling. May be involved in hh and dpp signaling by controlling the sulfation of heparan sulfate (HS).
Similarity
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
Mass
43.883 kDa
Sequence
MYIDTSASSRMTDNKGSVITINGGESAGNSPPSQRKSSTSESPPELRILCFDLTYYNRTTQFLLSCAGVFFLYILYGYLQELIFTVEGFKPYGWFLTLVQFGYYIGFGLVERRLEGYRISGGSFWNIEPEPRCIPMRTYLILAALTLGTMGLSNSSLGYLNYPTQVIFKCCKLIPVLVGSILIQGKRYGLLDFAAATCMCIGLAWFTLADSQMTPNFNLLGVAMISGALLCDAAIGNVQEKAMREFKAPSSEVVFYSYGLGFVYLFVIMLVTGNFFSGFAFCLEHPVETFGYGFLFSLSGYLGIQFVLALVRSSGAPIAATVTTARKAVTIAFSFVLFSKPFTLQYLWSGLIVVLGIYLNVYSKRNKLTLADVRQRIKQFGAKVARSPSRKFLIEV

Gene
Papst2
Protein
Adenosine 3'-phospho 5'-phosphosulfate transporter 2
Organism
Drosophila pseudoobscura pseudoobscura
Length
392 amino acids
Function
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Essential for viability. Involved in glycosaminoglycan synthesis and the subsequent signaling. May be involved in hh and dpp signaling by controlling the sulfation of heparan sulfate (HS) (By similarity).
Similarity
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
Mass
43.235 kDa
Sequence
MGDGQAGSVININGSASGQQAPTSNSPTLTRKSSSSELPPELRILCFDLTHYNQTTQFLLSCAGVFILYILYGYLQELIFTVEGFKPFGWFLTLVQFGYYIGFGLVERRLEAYRSGRRSLWNVEPAPRCIPMKTYLVLAALTLGTMGLSNSSLGYLNYPTQVIFKCCKLIPVLVGSILIQGKRYGPLDFAAASCMCIGLAWFTLADSQMTPNFNLLGVAMISGALLCDAAIGNVQEKAMKEHKAPSSEVVFYSYGLGFVYLFVIMLVTGNFFSGFAFCLEHPLQTFGYGFLFSLSGYLGIQFVLALVRSSGAPIAATVTTARKAVTIAFSFVLFSKPFTVQYLWSGLIVVLGIYLNVYSKKNKLTFADIRSRFKQFGFRLARSPSRKFLVEV

Gene
Papst2
Protein
Adenosine 3'-phospho 5'-phosphosulfate transporter 2
Organism
Aedes aegypti
Length
382 amino acids
Function
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Essential for viability. Involved in glycosaminoglycan synthesis and the subsequent signaling. May be involved in hh and dpp signaling by controlling the sulfation of heparan sulfate (HS) (By similarity).
Similarity
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
Mass
42.557 kDa
Sequence
MSVSNRNGNGSEVIYVGDRSTNRPPRNAPSPDEDRKEVKILFFDLTYYNTTTKFLLCCAGVFVLYLLYGYMQELIFTLDGFKPYGWFLTLVQFAYYTVFGYVERSLESKRVPRCIPMKTYVLLAFLTLGTMGLSNSSLGYLNYPTQVIFKCCKLVPVLIGSILIQGKKHGPLDFLAAIAMCLGLTLFTLADSQVSPNFNPFGVLLISLALLCDAAIGNVQEKAMREHKAPNNEVVIYSYGIGFVYLSVIMLLTGNLFSGITFCMKYPVETFGYAFLFSLSGYLGIQIVLTLVRTCGAPLAATVTTARKAVTIALSFVFFSKPFTINYLWSGLIVVLGIYLNVYSKRSKLTFADLNRTAERIYRKLVPQRGGSSSTKKLLLEV

Gene
Papst2
Protein
Adenosine 3'-phospho 5'-phosphosulfate transporter 2
Organism
Anopheles gambiae
Length
377 amino acids
Function
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Essential for viability. Involved in glycosaminoglycan synthesis and the subsequent signaling. May be involved in hh and dpp signaling by controlling the sulfation of heparan sulfate (HS) (By similarity).
Similarity
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
Mass
42.335 kDa
Sequence
MAGAKSEVIYLGDKDLNRNRHRDRDQSPEREIKILFFDLTHYNRTTQFLLCCGGVFALYLVYGYMQELIFTLEGFRPYGWYLTLVQFAYYTAFGYIERSVERTTVPRCIPLRTYALLAFLTLGTMGLSNSSVGYLNYPTQVIFKCCKLIPVLIGSVLIQGKKHGPMDFFAATAMCLGLILFTLADSQVQPDFNRFGVFLISLALLCDAAIGNVQEKAMREHRAPNNEVVIYSYGIGFVYLAVIMLLSGHLVQGVAFCARYPMETYGYAFLFSLTGYLGIQIVLTLVRTCGAPLAATVTTARKAVTIALSFVFFSKPFTIQYLWSGLIVVFGIYLNVYSKRSKLTFADLGRMASTVYRWVLRLPPAKDGGSRTSLLEV