Protein
23S rRNA (uracil(747)-C(5))-methyltransferase
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Function
Catalyzes the formation of 5-methyl-uridine at position equivalent to 747 (m5U747) in 23S rRNA (m5U859 in the P.abyssi numbering).
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Sequence
MRGIIKGVSNDGLGVLGEVLVPFAYPGDVVEVISTRERFGRTIARDFKLVKSSPIRVPGKCRYFGRCGGCLWQGLKYREQLKLKEEIFKRVTGVEAEIKGSPRIWFFRNISNFIVTVNGIGFKEFGMPRTVVSVDECPVFSERTKLYIRAMKRFLRETGLNPWNWKNGDVHYLQVREGKFTGEVMINVIAHIPPSGREELTEAFGFADSVYWSLKRDKRDDPKGIPTLIKGNEFIRESIEGLVYLIHPSTFFQTNSYALPILLKAVESFAEGSKVLDLYSGVGTFSLYLAKKGFEVTGVEVNEESVRVAKKSAEVNSLDVSFIPGRAEDAKLKGYETLIVDPPRKGLKDFSKRIAKEGPENLIYVSCNPSKFVLDYRNYLSKAYKIEDAVLIDMFPHTPHVEAVVKLRRR