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PRUNE2

Gene
PRUNE2
Protein
Protein prune homolog 2
Organism
Homo sapiens
Length
3088 amino acids
Function
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
Similarity
Belongs to the PPase class C family. Prune subfamily.
Mass
340.635 kDa
Sequence
MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLNIPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTLESAVVKVINPVEQSDANVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSILFKWMTMESEKISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKDLKELSDGEIKVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRRQIAVYSENMELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKEVINRRCPEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDANVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAEEHAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSEQESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTSPQGTNHLIEDFASLWHSGRSPTAMPEPWGNPTDDGEPAAVAPFPAWSAFGKEDHDEALKNTWNLHPTSSKTPSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTWTNSKPPKEDQNGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPELNDSSVALSSWGQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKSFDRKTPTFLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARVISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETEMQITAVEKEKRSSPETGTTGDVAWQISPKASFPKNEDNSQLEMLGFSADSTEWWKASPQEGRLIESPFERELSDSSGVLEINSSVHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSPFLEGNGKNSHEQLWNIQPRQPDPDADKFSQLVKLDQIKEKDSREQTFVSAAGDELTPETPTQEQCQDTMLPVCDHPDTAFTHAEENSCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDGSTPSEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPFSLKADGENPDILTHCEHDSNSQASDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAELDSENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNSTGLQVSEKGASPDMAPILEPVDRRIPRIENVATSIFVTHQEPTPEGDGSWISDSFSPESQPGARALFDGDPHLSTENPALVPDALLASDTCLDISEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDLGKQDICSSEASWGDFEYDVMGQNIDEDLLREPEHFLYGGDPPLEEDSLKQSLAPYTPPFDLSYLTEPAQSAETIEEAGSPEDESLGCRAAEIVLSALPDRRSEGNQAETKNRLPGSQLAVLHIREDPESVYLPVGAGSNILSPSNVDWEVETDNSDLPAGGDIGPPNGASKEISELEEEKTIPTKEPEQIKSEYKEERCTEKNEDRHALHMDYILVNREENSHSKPETCEERESIAELELYVGSKETGLQGTQLASFPDTCQPASLNERKGLSAEKMSSKSDTRSSFESPAQDQSWMFLGHSEVGDPSLDARDSGPGWSGKTVEPFSELGLGEGPQLQILEEMKPLESLALEEASGPVSQSQKSKSRGRAGPDAVTLQAVTHDNEWEMLSPQPVQKNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGVLSPSAADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPTANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP

Gene
Prune2
Protein
Protein prune homolog 2
Organism
Mus musculus
Length
3084 amino acids
Function
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
Similarity
Belongs to the PPase class C family. Prune subfamily.
Mass
339.516 kDa
Sequence
MEEFLQRAKSKLDRSKQLEQVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVLNIPRTEFNYFTETRFILEELNIPESFHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRTLESAVVRVINPGEQSDGELGFPETSSSLVLKELLREAPELITQQLAHLLRGSILFTWMSMDPELPEKQEEILSILEEQFPNLPPRDDIINVLQESQLSAQGLSLEQTMLKDLKELSDGEIKVAISTVNMTLEDYLLHGNITSDLKAFTDKFGFDVLILISSFTWEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTSDQVFLLLKEVINRRCAEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQADGNIDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGDGGAPHHSLLPGFDSYSPIPEGIVAEEHAHSGEHSEHFDLFNFDSAPIASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGINMSNYSSSSLLSEAGKDSLVEFDEEFIQRQESSGDNSERNLSLTCFAGEEPSSPERLKNPGKMIPPTPMNSFVEISPSNEEPTPLYPEDIIQNAIDTGHLGPPQARARCRSWWGGLEIDSKNVVDTWNASEQESVFQSPEPWKDPKPEPVERRTSDSTFQPKSLEFSKSDPWESEFGQPELGNKEAQDQKEESLQYQHLPTVRPHLTDASPHGTNHLIEDFAALWHSGHSPTTMPEPWGNPTDAGEAAVTMSFPTWGAFDKEEDNADTLKNTWNLHPTNNETPSGQEPSEWAMGQSGFSFPAADLLDNPLIEVNKDAAPEIWGKNNSSKDTSLTSGSPTSDLGQTWNNSKLPGEDQNGLVDPKATGKVYEKEGSWSLFEESAKKRGADVLAPWEDSFLSYKCSDYSASNIGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEIANKPVDKDNGFEAKDAEFPAEGLEVLATSSQQSQRNRIGSGPGNLDMWALPHTEDKPEGNDAHHPDSDALKTEHAEDKNASMEDDVRESSPSSYDDPSMMRLYEANRQLTLLHSNTNSRQAAPDSLDTWNRVTLEDTQSTATISDMDNDLDWDDCSGGVAISGDGQAEGYIAANSEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGDPGPSEYQTLNEKTGQLIANSIWDSVMGDKNMPSFRLPSPPNTVDMEHGTWPSESPRHSNGKDSHMLEASRLSESGGLTSQPVNQDTWGDSQGDTASSVTGLASPEHFAQSDPWTGHTYGQSESEIEGLVASDCEHLDKEAALGSGVNGAPWAFGKKPRDQEFSSSDAFEHQDISSASGKISSLSVTSSPQSEEPGEALEVEKEPFILDSLAVQTETFTWDLQSKDTHEESLVDHRNLGEANTTLDRINPMKNRPLSGMELEKTEACTILKPERANGKLLYESSQDFGVWDGPMDSDVWDSHISYETAMNSTGQRTEERSLEALSPGNYDRDSLSSGCTHSSASSPDLHDSSVALSSWTYGPSAEHQKENHDDANKQIHQESELFTTEAHVDVITEMKDFVENREDGFGKMSNQEDPQFPEIPNDPFNSGPSSSSSSLGADKYSEYSHAYQEGDLTTKRQEENELGFLEIVEPEGTRIISTSSGSGNDSGGDEELLEKELHLATVAQSEAGACTSLHEPAFSATEHSKPEFSVFVGSLESIEKENKSSPFSDSQQSSPGQWILSPLMQADTQDTCKEETRAAETGTMDTTWHGSASTEAKNGDPDKLEMLGFSADSTEWWNAGAQEGRANAGMSAEELSNSEGELEPTSPVFQNAGPWSLPIQNDSEPVDTGSTNPFRGKLKSPVLDSHGDKSQEKLWNIQPKQLDSDANQLSQLVILDQMKDKDSGQQTAMSPAAGDLPAETLTQGQGRESMLSVWDRAEPALTHRDENGCVSTGVSPTECQQENQWEPEKPYLSHVTHSSTPTENALESNAPTQLMRKLDSDWNSPSPSEPQHNFVPDILHGNFEEGGQLASASPDLWMDVKQPFSFKVDSENPDILTHCDHDSNSQASSSPDVCHDSEGEQKMEKHTAVYLGLEVEPSEFSLTEPNMNDEPTWEPEQESLPHNSELHSEHAMPLPPIDSQNDINNSSKPASSRSSPEPSDMRGDNNTSVTSMEEDTNPEVEAVDSVTIPGHFPRSEDADTFEAHQEVSVEVDDSWVSKDLCPESQTGTRALLDCEQPFASESPAVLTDIFLTSDTCLDVSEAALDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEELMREPEHFLYGGDLPSEESALKQSLTPYTPPFDLSYLTEPTGCTETAQGAESPGDESLGSDAAEMLLSALPDHREEDKAETNIRKPRYQMTVLHIHEDPEALSSPVGGTGSNNESSPSNIDWEIETDNSDSPAGGDMKPPNGKEILELEEDEKVIPTKGPKQTELEYKEEKQPEQSEDHQVLAVDYILVSHEKDSPLKPEAREARENIPELEQLSIGSRETGLPETQLSGTPDTCQSEFLNDVKVHSAERMSSSSNHESASLENPAQDQSWMVLSHSEVGDPPTETRDSGPESPGRTPEPFLSLSLDKGPKSQVLERNKPLNSLALEEVAGLSSQSRNIERQGQAGLDAVPTQAATHDNEWEMLSPQLSRKNRNPPQEMEEETQCPEPGPRKPRLKGPPSEDEGMDIHFEEGVLSPSAADMRPEPPNSLDLNGSHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTNHEDPTANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVTSLSELSGLIPMDCIHIPESIIKYDEEKSFKRSVRLDEELREASEAAKTSCLYNDPEMSSMEKDIDMKLKEKP

Gene
PRUNE2
Protein
Protein prune homolog 2
Organism
Pongo abelii
Length
323 amino acids
Function
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
Mass
36.838 kDa
Sequence
MDIPFEEGVLSPSAADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYAGHEDPTANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAATRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP
Protein
Protein prune homolog 2: PRUNE2

Gene
Prune2
Protein
Protein prune homolog 2
Organism
Rattus norvegicus
Length
322 amino acids
Function
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
Mass
36.98 kDa
Sequence
MDIHFEEGVLSPSATDMRPEPPNSLDLNGSHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYPGHEDPMANRSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIIKYDEEKSFKRSVRTSCLYNDPEMTSMEKDIDMKLKEKP
Protein
Protein prune homolog 2: Prune2

Gene
Prune2
Protein
Protein prune homolog 2
Organism
Xenopus tropicalis
Length
316 amino acids
Mass
36.048 kDa
Sequence
MDIPLDAAEIRPEPPNSLDLNGSSTRKIKLTAPNINLSLDHSEGSILSDDNLDTPDELDINVDDLDTPDEADSFDYTGQDDQPALGEAVQEDFESIQEYTAEEERADNRLWRTVVIGEQEQRIDMKVIEPYKKVISHGGYYGEGVNAIIVFAACFLPDSSRPDYNYVMENLFLYVISTLELMVAEDYMVVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILALTRPFISSKFSSKIKYVSTLAELSELIPMEYVHIPETIVKLDEELRESESPKAGCLPNEPEMNTLEEEFENKMGDND
Protein
Protein prune homolog 2: Prune2