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POLB

Gene
POLB
Protein
DNA polymerase
Organism
Acanthamoeba polyphaga mimivirus
Length
1740 amino acids
Similarity
Belongs to the DNA polymerase type-B family.
Mass
201.945 kDa
Sequence
MPSETIDSTKQFEFQISDWNSYHELDQEEEEKYVIQLFGRTEDDHDVCLKVTGYTPFFYVEIPKQWKQRQVDKFVEILKNKVQYHCKKNLDEDFDLSKSLIKYAMVKKHKFYNFRNKQLYNFLLLVFKSHTAMKEFSSILARPLEAKGLTNKPMLYQRYESNIEPHIRFMHINNLSSCGWASIDKDKLKKIPEYSNCDYSFSVNWKDVKPSNNDDRMAPFKIMGYDIECVSCDQNFPQAERPSDKIIQIGITMYRYGSMKCYEQHILTLKKCAPIEGVNVECYKKEKGLLRGFAKKIAELRPDFKTGYNNFGFDDKYIYDRILRIDKREGKKQGVNINALKNKFMDEILRTIGKVNNNYLIENEGLDRIPIYTTVKDKKISSKASRFIQIRGGTYVENGNNLKYVQSPGITYFEVKNLSSSALGDNELKFIQIPGVLSIDMMKVIQRDHRLIGYKLDNVSANFITEKADKIIEMPHNQEDSDSEKEDEDTDDKTYDVNIYTKSTKALEKDSYIQIMVNDGYSSSPLSEGAKYKVYDIQTITEKKLNEKTNKEEIFVYQAIKTKICQKDIQQLRETIKNPLLGISWTFAKDDMHHTKINEYFEEGDPKKIRQIAKYCLKDCKLVNLLLAKLEIIVNSVGMAKVCHVPLSYLFLRGQGVKIFSLVSKKCREKNFLIPVLRRKSKDNEGDEDETYEGATVITPKPNVYLSPIGVLDYSSLYPNSMRERNLSQECYVDDSKYDNLPGYIYHDVEIILKDKKGKILRNIDGTPQKEYHRFAQEIITDEQINRELKDIFDKINTVFENNVAIIQNQKYFTEKNISELIDKHKNISDSKIEDIEFDESLSDKRKNKLVDAEKDSLDKNIGFYQKIKSQIDKIKLDSKIEIDNLSKNLNEEEKSKQINKMELNTKNLISKVFSKYLITEQQREELIVLEKERAKRSVNAEKAKVYNTVDGITVRYGILPEILTELLNKRKETNGKLANEKDPFVKAILNALQLAFKVTANSLYGQTGAPTSPLYFIAIAACTTAIGRERLHYAKKTVEDNFPGSEVIYGDSVTGDTPIITRHQNGDINITTIEELGSKWKPYEIFKAHEKNSNRKFKQQSQYPTDSEVWTAKGWAKIKRVIRHKTVKKIYRVLTHTGCIDVTEDHSLLDPNQNIIKPINCQIGTELLHGFPESNNVYDNISEQEAYVWGFFMGDGSCGSYQTKNGIKYSWALNNQDLDVLNKCKKYLEETENIQFKILDTMKSSSVYKLVPIRKIKYMVNKYRKIFYDNKKYKLVPKEILNSTKDIKNSFLEGYYAADGSRKETENMGCRRCDIKGKISAQCLFYLLKSLGYNVSINIRSDKNQIYRLTFSNKKQRKNPIAIKKIQLMNETSNDHDGDYVYDLETESGSFHAGVGEMIVKNTDSIFINFHIKDENGEEKTDKEALMKTIAKCQRAAKLINQNVPKPQSIVYEKTLHPFILVAKKKYVGLLFEKSPDKYFLKSMGIVLKRRDNAPIVKIVVGGIIDNILKNRDIDKAIEYTKIVLDKLMNGEYPMDKFIISKTLKSRYKKPSTIAHKVLADRMAVRDPGNKPQINDRIPFVYIVKDMGKKKKKDILQGDLIEHPEYVIANNLKIDYLYYLEHQIINPASQILELMMDTKDVQKFFNKYIIDEQNKRKGAQSLTKWMDFSKLPKESGSKTAKKPYQSQKLQKTKSSNKSQIDPKYINLIKNKSRKHECQNMNKWISSTDKCTDDWEPIVE
Protein
DNA polymerase: POLB

Gene
POLB
Protein
DNA polymerase
Organism
Acanthamoeba polyphaga mimivirus
Length
1740 amino acids
Similarity
Belongs to the DNA polymerase type-B family.
Mass
201.945 kDa
Sequence
MPSETIDSTKQFEFQISDWNSYHELDQEEEEKYVIQLFGRTEDDHDVCLKVTGYTPFFYVEIPKQWKQRQVDKFVEILKNKVQYHCKKNLDEDFDLSKSLIKYAMVKKHKFYNFRNKQLYNFLLLVFKSHTAMKEFSSILARPLEAKGLTNKPMLYQRYESNIEPHIRFMHINNLSSCGWASIDKDKLKKIPEYSNCDYSFSVNWKDVKPSNNDDRMAPFKIMGYDIECVSCDQNFPQAERPSDKIIQIGITMYRYGSMKCYEQHILTLKKCAPIEGVNVECYKKEKGLLRGFAKKIAELRPDFKTGYNNFGFDDKYIYDRILRIDKREGKKQGVNINALKNKFMDEILRTIGKVNNNYLIENEGLDRIPIYTTVKDKKISSKASRFIQIRGGTYVENGNNLKYVQSPGITYFEVKNLSSSALGDNELKFIQIPGVLSIDMMKVIQRDHRLIGYKLDNVSANFITEKADKIIEMPHNQEDSDSEKEDEDTDDKTYDVNIYTKSTKALEKDSYIQIMVNDGYSSSPLSEGAKYKVYDIQTITEKKLNEKTNKEEIFVYQAIKTKICQKDIQQLRETIKNPLLGISWTFAKDDMHHTKINEYFEEGDPKKIRQIAKYCLKDCKLVNLLLAKLEIIVNSVGMAKVCHVPLSYLFLRGQGVKIFSLVSKKCREKNFLIPVLRRKSKDNEGDEDETYEGATVITPKPNVYLSPIGVLDYSSLYPNSMRERNLSQECYVDDSKYDNLPGYIYHDVEIILKDKKGKILRNIDGTPQKEYHRFAQEIITDEQINRELKDIFDKINTVFENNVAIIQNQKYFTEKNISELIDKHKNISDSKIEDIEFDESLSDKRKNKLVDAEKDSLDKNIGFYQKIKSQIDKIKLDSKIEIDNLSKNLNEEEKSKQINKMELNTKNLISKVFSKYLITEQQREELIVLEKERAKRSVNAEKAKVYNTVDGITVRYGILPEILTELLNKRKETNGKLANEKDPFVKAILNALQLAFKVTANSLYGQTGAPTSPLYFIAIAACTTAIGRERLHYAKKTVEDNFPGSEVIYGDSVTGDTPIITRHQNGDINITTIEELGSKWKPYEIFKAHEKNSNRKFKQQSQYPTDSEVWTAKGWAKIKRVIRHKTVKKIYRVLTHTGCIDVTEDHSLLDPNQNIIKPINCQIGTELLHGFPESNNVYDNISEQEAYVWGFFMGDGSCGSYQTKNGIKYSWALNNQDLDVLNKCKKYLEETENIQFKILDTMKSSSVYKLVPIRKIKYMVNKYRKIFYDNKKYKLVPKEILNSTKDIKNSFLEGYYAADGSRKETENMGCRRCDIKGKISAQCLFYLLKSLGYNVSINIRSDKNQIYRLTFSNKKQRKNPIAIKKIQLMNETSNDHDGDYVYDLETESGSFHAGVGEMIVKNTDSIFINFHIKDENGEEKTDKEALMKTIAKCQRAAKLINQNVPKPQSIVYEKTLHPFILVAKKKYVGLLFEKSPDKYFLKSMGIVLKRRDNAPIVKIVVGGIIDNILKNRDIDKAIEYTKIVLDKLMNGEYPMDKFIISKTLKSRYKKPSTIAHKVLADRMAVRDPGNKPQINDRIPFVYIVKDMGKKKKKDILQGDLIEHPEYVIANNLKIDYLYYLEHQIINPASQILELMMDTKDVQKFFNKYIIDEQNKRKGAQSLTKWMDFSKLPKESGSKTAKKPYQSQKLQKTKSSNKSQIDPKYINLIKNKSRKHECQNMNKWISSTDKCTDDWEPIVE
Protein
DNA polymerase: POLB

Gene
polB
Protein
DNA polymerase 2
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Length
803 amino acids
Similarity
Belongs to the DNA polymerase type-B family.
Mass
91.739 kDa
Sequence
MKGSDATLLSFQLLDVSYEMRGSTPVIILWGRGADGSRVVVFYGEFRPYFYVLPDGSVGLDQLAAMIRRLSRPSSPILSVERVRRRFIGREVEALKVTTLVPASVREYREAVRRLGGVRDVLEADIPFALRFIIDFNLYPMRWYVAEVREVAVPHGYSVDRAYTLSGDIREDETRIQEDPLKGLRVMAFDIEVYSKMRTPDPKKDPVIMIGLQQAGGEIEILEAEDRSDKKVIAGFVERVKSIDPDVIVGYNQNRFDWPYLVERARVLGVKLAVGRRSVEPQPGLYGHYSVSGRLNVDLLDFAEELHEVKVKTLEEVADYLGVVKIGERVTLEWWQIGEYWDDPSKREILRKYLRDDVRSTMGLAEKFLPFGAELSQVSGLPLDQVMAASVGFRLEWRLIREAAKLGELVPNRVERSEGRYAGAIVLRPKPGVHEDIAVLDFASMYPNIMVKYNVGPDTLVRPGEEYGEEEVYTAPEVGHKFRKSPPGFFKKILERFLSWRRQIRSEMKKHPPDSPEYKLLDERQKAIKLLANASYGYMGWPHARWYCRECAEAVTAWGRSIIRTAIRKAGELGLEVIYGDTDSLFVKNDPEKVERLIRFVEEELGFDIKVDKVYRRVFFTEAKKRYVGLTVDGKIDVVGFEAVRGDWSELAKETQFKVAEIVLKTGSVDEAVDYVRNIIEKLRRGQVDMRKLVIWKTLTRPPSMYEARQPHVTAALLMERAGIKVEPGAKIGYVVTKGSGPLYTRAKPYFMASKEEVDVEYYVDKQVVPAALRILQYFGVTEKRLKGGGRQSTLLDFMRRGK
Protein
DNA polymerase 2: polB

Gene
polB
Protein
DNA polymerase II
Organism
Escherichia coli (strain K12)
Length
783 amino acids
Function
Thought to be involved in DNA repair and/or mutagenesis. Its processivity is enhanced by the beta sliding clamp (dnaN) and clamp loader (PubMed:1999435, PubMed:1534562).
Similarity
Belongs to the DNA polymerase type-B family.
Mass
90.053 kDa
Sequence
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
Protein
DNA polymerase II: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Length
622 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
70.283 kDa
Sequence
MDEFVKGLMKNGYLITPSAYYLLVGHFNEGKFSLIELIKFAKSRETFIIDDEIANEFLKSIGAEVELPQEIKEGYISTGEGSQKVPDHEELEKITNESSVESSISTGETPKTEELQPTLDILEEEIGDIEGGESSISTGDEVPEVENNNGGTVVVFDKYGYPFTYVPEEIEEELEEYPKYEDVTIEINPNLEVVPIEKDYEIKFDVRRVKLKPPKVKSGSGKEGEIIVEAYASLFRSRLRKLRRILRENPEVSNVIDIKKLKYVKGDEEVTIIGLVNSKKETSKGLIFEVEDQTDRVKVFLPKDSEDYREALKVLPDAVVAFKGVYSKRGIFFANRFYLPDVPLYRKQKPPLEEKVYAVLTSDIHVGSKEFCEKAFIKFLEWLNGYVESKEEEEIVSRIRYLIIAGDVVDGIGIYPGQYSDLIIPDIFDQYEALANLLSNVPKHITIFIGPGNHDAARPAIPQPEFYEEYAKPLYKLKNTVIISNPAVIRLHGRDFLIAHGRGIEDVVSFVPGLTHHKPGLPMVELLKMRHLAPTFGGKVPIAPDPEDLLVIEEVPDLVQMGHVHVYDTAVYRGVQLVNSATWQAQTEFQKMVNIVPTPGLVPIVDVESARVIKVLDFSRWC
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Length
619 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
69.395 kDa
Sequence
MDELVKALERAGYLLTPSAYYLLVDHFKEGKFSLVELVKFAKSKGVFIIDGDLAYEFLQFLGLGVPQEIKESYISTGEEAEKTVESQETRASELEEGGVSQVSSGELQELKEESPEISTTEEEIGGLELVQSSISTGSEVEYNNGENGESVVVLDKYGYPILYAPEEIGEEKEYSKYEDVVIEWNPSVTPVQIEKNYEVKFDVRQVKLRPPKVKNGSGKEGEIIVEAYASLFKSRLSKLKRILRENPEISNVVDIGKLNYVSGDEEVTIIGLVNSKRETNRGLIFEVEDKTGIVKVFLPKDSEDYREAFKVLPDAVVAFKGFYSKKGIFFANKFYLPDVPLYRKQKPPLEEKVYAILISDIHVGSREFCEKAFLKFLEWLNGHVESKEEEEIVSRVKYLIIAGDVVDGIGIYPGQYSDLVIPDIFDQYEALANLLANVPEHITMFIGPGNHDAARPAIPQPEFYKEYAKPIYKLKNAIIISNPAVIRLHGRDFLIAHGRGIEDVVSFVPGLTHHKPGLPMVELLKMRHLAPTFGGKVPIAPDPEDLLVIEEVPDLVQMGHVHVYDAVVYRGVQLVNSATWQAQTEFQKMVNIVPTPAKVPVVDVESARVVKVLDFSGWC
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
613 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
69.184 kDa
Sequence
MDEFVKSLLKANYLITPSAYYLLREYYEKGEFSIVELVKFARSRESYIITDALATEFLKVKGLEPILPVETKGGFVSTGESQKEQSYEESFGTKEEISQEIKEGESFISTGSEPLEEELNSIGIEEIGANEELVSNGNDNGGEAIVFDKYGYPMVYAPEEIEVEEKEYSKYEDLTIPMNPDFNYVEIKEDYDVVFDVRNVKLKPPKVKNGNGKEGEIIVEAYASLFRSRLKKLRKILRENPELDNVVDIGKLKYVKEDETVTIIGLVNSKREVNKGLIFEIEDLTGKVKVFLPKDSEDYREAFKVLPDAVVAFKGVYSKRGILYANKFYLPDVPLYRRQKPPLEEKVYAILISDIHVGSKEFCENAFIKFLEWLNGNVETKEEEEIVSRVKYLIIAGDVVDGVGVYPGQYADLTIPDIFDQYEALANLLSHVPKHITMFIAPGNHDAARQAIPQPEFYKEYAKPIYKLKNAVIISNPAVIRLHGRDFLIAHGRGIEDVVGSVPGLTHHKPGLPMVELLKMRHVAPMFGGKVPIAPDPEDLLVIEEVPDVVHMGHVHVYDAVVYRGVQLVNSATWQAQTEFQKMVNIVPTPAKVPVVDIDTAKVVKVLDFSGWC
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
594 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
69.145 kDa
Sequence
MEIINKFLDLEALLSPTVYEKLKNFDEEKLKRLIQKIREFKKYNNAFILLDEKFLDIFLQKDLDEIINEYKDFDFIFYYTGEEEKEKPKEVKKEIKKETEEKIEKEKIEFVKKEEKEQFIKKSDEDVEEKLKQLISKEEKKEDFDAERAKRYEHITKIKESVNSRIKWIAKDIDAVIEIYEDSDVSGKSTCTGTIEDFVKYFRDRFERLKVFIERKAQRKGYPLKDIKKMKGQKDIFVVGIVSDVDSTRNGNLIVRIEDTEDEATLILPKEKIEAGKIPDDILLDEVIGAIGTVSKSGSSIYVDEIIRPALPPKEPKRIDEEIYMAFLSDIHVGSKEFLHKEFEKFIRFLNGDVDNELEEKVVSRLKYICIAGDLVDGVGVYPGQEEDLYEVDIIEQYREIAMYLDQIPEHISIIISPGNHDAVRPAEPQPKLPEKITKLFNRDNIYFVGNPCTLNIHGFDTLLYHGRSFDDLVGQIRAASYENPVTIMKELIKRRLLCPTYGGRCPIAPEHKDYLVIDRDIDILHTGHIHINGYGIYRGVVMVNSGTFQEQTDFQKRMGISPTPAIVPIINMAKVGEKGHYLEWDRGVLEVRY
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Length
508 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
54.539 kDa
Sequence
MPLEPSVRVVRELTSRGYNADREAVTLLAGADDPGAAVERAVAAAAADAATLTVSDVRAVLDAHTASSAAQTSAPASTPPDEATTHTDPSATDTPPNHDGGRAATADARSVEIDGDMTGASTGTGEYQDFVSVFRDRYDRLAAQLRGRVNHRPTSALASMPGGSDAAIVGMVNDIRSTTSGHWRVELEDTNGVFPVLVLKDRDVSDLVDDLLLDEVIAVSGTLADDGTILFADDIYFPEVPRTYSPSTADRSVQAALISDVHVGSQEFAADAWRSFADWLHTPAAESVEYLLIAGDMVEGVGVYPGQDEELDIVDIYDQYETFAEHLKDVPGDMEIVMIPGNHDAVRLAEPQPAFDEELRSIMRAHDARITSNPSTVTIDGVSVLLYHGVSLDEVIAEHPSDDVTYDDPQNAMELLLKKRHVAPPFGGRTRLAPEAEDHLAIDTVPDVFHTGHVHKLGVGIHHNVRLVNSGCWQHQTAFQESVNISPDVATAPILDLDTLDITVHKFS
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
508 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
54.539 kDa
Sequence
MPLEPSVRVVRELTSRGYNADREAVTLLAGADDPGAAVERAVAAAAADAATLTVSDVRAVLDAHTASSAAQTSAPASTPPDEATTHTDPSATDTPPNHDGGRAATADARSVEIDGDMTGASTGTGEYQDFVSVFRDRYDRLAAQLRGRVNHRPTSALASMPGGSDAAIVGMVNDIRSTTSGHWRVELEDTNGVFPVLVLKDRDVSDLVDDLLLDEVIAVSGTLADDGTILFADDIYFPEVPRTYSPSTADRSVQAALISDVHVGSQEFAADAWRSFADWLHTPAAESVEYLLIAGDMVEGVGVYPGQDEELDIVDIYDQYETFAEHLKDVPGDMEIVMIPGNHDAVRLAEPQPAFDEELRSIMRAHDARITSNPSTVTIDGVSVLLYHGVSLDEVIAEHPSDDVTYDDPQNAMELLLKKRHVAPPFGGRTRLAPEAEDHLAIDTVPDVFHTGHVHKLGVGIHHNVRLVNSGCWQHQTAFQESVNISPDVATAPILDLDTLDITVHKFS
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
488 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
54.586 kDa
Sequence
MVIKNIDAATVAKKFLVRGYNIDPKAAELICKSGLFSDELVDKICRIANGGFIIEKSVVEEFLRNLSNLKPATLTPRPEERKVEEVKASCIALKVIKDITGKSSCQGNVEDFLMYFNSRLEKLSRIIRSRVNTTPIAHAGKVRGNVSVVGMVNEVYERGDKCYIRLEDTTGTITCVATGKNAEVARELLGDEVIGVTGLLKGSSLYANRIVFPDVPINGNGEKKRDFYIVFLSDTHFGSKEFLEKEWEMFVRWLKGEVGGKKSQNLAEKVKYIVIAGDIVDGIGVYPGQEDDLAISDIYGQYEFAASHLDEIPKEIKIIVSPGNHDAVRQAEPQPAFEGEIRSLFPKNVEHVGNPAYVDIEGVKVLIYHGRSIDDIISKIPRLSYDEPQKVMEELLKRRHLSPIYGGRTPLAPEREDYLVIEDVPDILHCGHIHTYGTGFYRGVFMVNSSTWQAQTEFQKKVNLNPMPGNVAVYRPGGEVIRLRFYGE
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Length
488 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
55.577 kDa
Sequence
MVIWFFYGFRKIMHLSLKRIIVKCKMSQLDRTSLIQYFNSNGVLISPEALDKLIKYSSSSLIEDLIKNSDGYIDEKYVERYVSRPKVRNDYEVYLPDVRFNASIEDFRKMFVSKYEKLSKIITSSSSMRGSISIKTAKRSQGEVKVVGMVSEVSMTKNGHKRIVIEDLDDSITAIVMKDRGPVNEIILEDEVIGIIGSVSQSSKDPVIFVNEIIRPDIPYRVIDEEKHEPVYVASISDIHVGSKTFRKNEFEAMVRWISGSDPDASRVKYLILSGDVVDGIGVYPDQENDLEILNPLEQYANLAEYLVDVPEDVKVFVMPGNHDTVRLSEPQPVFPGKIRDLFEPNVAFLPNPYNLKLEGKNVLVYHGMSLNDMIELIPGANYDSIGKAIEAILVRRHLSPKYGGNTPMIPSAVDYHVIEEVPDIFITGHIHSHYIGNYKGVRYVNSSTWQSQTEYQKMMNFNPKPSKLTLFDLYSRSVIVKDFDTTL
Protein
DNA polymerase II small subunit: polB

Gene
polB
Protein
DNA polymerase II small subunit
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
482 amino acids
Function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Similarity
Belongs to the DNA polymerase delta/II small subunit family.
Mass
54.376 kDa
Sequence
MNEIIGKFAREGILIEDNAYFRLREMDDPASVSSELIVKIKSNGGKFTVLTSEMLDEFFEIDNPAEIKARGPLMVPAERDFDFEVISDTSNRSYTSGEIGDMIAYFNSRYSSLKNLLSKRPELKGHIPIADLRGGEDVVSIIGMVNDVRNTKNNHRIIELEDDTGEISVVVHNENHKLFEKSEKIVRDEVVGVHGTKKGRFVVASEIFHPGVPRIQEKEMDFSVAFISDVHIGSQTFLEDAFMKFVKWINGDFGSEEQRSLAADVKYLVVAGDIVDGIGIYPGQEKELLIRDIHEQYEEAARLFGDIRSDIKIVMIPGNHDSSRIAEPQPAIPEEYAKSLYSIRNIEFLSNPSLVSLDGVRTLIYHGRSFDDMAMSVNGLSHERSDLIMEELLEKRHLAPIYGERTPLASEIEDHLVIDEVPHVLHTGHVHINAYKKYKGVHLINSGTFQSQTEFQKIYNIVPTCGQVPVLNRGVMKLLEFS
Protein
DNA polymerase II small subunit: polB

Gene
polb
Protein
DNA polymerase beta
Organism
Danio rerio
Length
336 amino acids
Function
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity).
Similarity
Belongs to the DNA polymerase type-X family.
Mass
38.566 kDa
Sequence
SKRKAPQESLNEGITDFLVELANYERNVNRAIHKYNAYRKAASVIAKYPQKIKSGTEAKKLDGVGAKIAEKIDEFLTTGKLRKLEKIRNDDTSSSINFLTRVTGIGPAAARKFFDEGVRNLEDLKKIEHKLNHHQQIGLKYFEEFEKRIPRSEMQKMEALILKELDIVDPEYIGTICGSYRRGAESSGDIDILLTHPDFTSQSEKQPKLLHAVVDHLESIGFITDTLSKGDTKFMGVCQLQKEKEEEEEESLHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRTHALEKGFTLNEYTIRPLGVTGVAGEPLLVDSEKDIFEYIQWKYREPKDRSE
Protein
DNA polymerase beta: polb

Gene
POLB
Protein
DNA polymerase beta
Organism
Bos taurus
Length
335 amino acids
Function
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity).
Similarity
Belongs to the DNA polymerase type-X family.
Mass
38.267 kDa
Sequence
MSKRKAPQETLNGGITDMLTELANFEKNVNQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLSEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESAKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
Protein
DNA polymerase beta: POLB

Gene
POLB
Protein
DNA polymerase beta
Organism
Homo sapiens
Length
335 amino acids
Function
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Similarity
Belongs to the DNA polymerase type-X family.
Mass
38.178 kDa
Sequence
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
Protein
DNA polymerase beta: POLB

Gene
Polb
Protein
DNA polymerase beta
Organism
Mus musculus
Length
335 amino acids
Function
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity).
Similarity
Belongs to the DNA polymerase type-X family.
Mass
38.288 kDa
Sequence
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEIKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVHFITDTLSKGETKFMGVCQLPSEKDGKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
Protein
DNA polymerase beta: Polb

Gene
Polb
Protein
DNA polymerase beta
Organism
Rattus norvegicus
Length
335 amino acids
Function
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Similarity
Belongs to the DNA polymerase type-X family.
Mass
38.327 kDa
Sequence
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
Protein
DNA polymerase beta: Polb

Gene
polb
Protein
DNA polymerase beta
Organism
Xenopus laevis
Length
334 amino acids
Function
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity).
Similarity
Belongs to the DNA polymerase type-X family.
Mass
38.294 kDa
Sequence
MSKRKAPQESPNEGITDFLVELANYERNVNRAIHKYNAYRKAASVIAKYPTKIKSGTEAKKLDGVGAKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPAAARKFFDEGIKTLDDLRNNEHKLNHHQKIGLKHFDDFEKRIPRKEMLQMQEIILDKVNNLDPEYIATVCGSFRRGAESSGDMDILLTHPDFTSESAKQPRLLHQVVQCLEDCNFITDTLVKGDTKFMGVCQLPCESDQDYPYRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRTHALEKGFTLNEYTLRPLGVTGIAGEPLPIDSEKDIFDYIQWKYREPKDRSE
Protein
DNA polymerase beta: polb