Protein
POC1 centriolar protein homolog A
Function
Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation (By similarity).
Similarity
Belongs to the WD repeat POC1 family.
Sequence
MTAHCPEDPSLERHFKGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSFHPSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDYGEVLRVQRPPATRASSSGTLPEVDPLVPPGRGRSQESMQSHSQEPVSVPQSLTSTLEHIVGQLDVLTQTVSILEQRLTLTEDKLKQCLENQQLIMQRTTP