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PNC1

Gene
PNC1
Protein
Peroxisomal adenine nucleotide carrier 1
Organism
Arabidopsis thaliana
Length
322 amino acids
Function
Peroxisomal adenine nucleotide transporter catalyzing the counterexchange of ATP with AMP. ATP is needed by reactions that generate acyl-CoA for peroxisomal fatty acid beta-oxidation during postgerminative growth. Required for the beta-oxidation reactions involved in auxin biosynthesis and for the conversion of seed-reserved triacylglycerols into sucrose that is necessary for growth before the onset of photosynthesis.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Mass
35.551 kDa
Sequence
MGVDLESVSEATSGAIGSLLSTTILYPLDTCKSKFQAEVRARGQQKYRYLSDVMWEAISKGQVFSLYQGLGTKNFQSFISQFIYFYSYSYFKRVHSERTGSKSIGTKANLLIAAAAGACTSVLIQPLDTASSRMQTSEFGESKGLWKTLTEGSWADAFDGLGISLLLTSNPAIQYTVFDQLKQHLLKQKNAKAENGSSPVVLSAFMAFVLGAVSKSVATVLTYPAIRCKVMIQAADESKENETKKPRRRTRKTIPGVVYAIWRKEGMLGFFKGLQAQILKTVLSSALLLMIKEKITATTWILILAIRRTLFLTNTKGKLRSP

Gene
PNC1
Protein
Peroxisomal adenine nucleotide carrier 1
Organism
Glycine max
Length
318 amino acids
Function
Peroxisomal adenine nucleotide transporter catalyzing the counterexchange of ATP with AMP. ATP is needed by reactions that generate acyl-CoA for peroxisomal fatty acid beta-oxidation during postgerminative growth. Required for the conversion of seed-reserved triacylglycerols into sucrose that is necessary for growth before the onset of photosynthesis.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Mass
34.769 kDa
Sequence
MNVDLESLAEATSGAIGSLISTTILYPLDTCKTKYQAEARSSGRTKYRNLTDVLLEAISNRQVLSLYQGLGTKNLQSFISQFVYFYGYSYFKRLYLEKSGYKSIGTKANLVIAAAAGACTAIATQPLDTASSRMQTSEFGKSKGLLKTLTEGNWSDAFDGLSISLLLTSNPAIQYTVFDQLKQRALKNKQDNADKGTSPASLSAFMAFLLGAISKSIATCLTYPAIRCKVIIQAADSAEETSKTKIKSQKTVLSVLYGIWKREGILGYFKGLHAQILKTVLSSALLLMIKEKISASTWVLILALKRYLLLPRGKVKNL

Gene
PNC1
Protein
Cationic peroxidase 1
Organism
Arachis hypogaea
Length
316 amino acids
Function
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Similarity
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
Mass
33.518 kDa
Sequence
MALPISKVDFLIFMCLIGLGSAQLSSNFYATKCPNALSTIKSAVNSAVAKEARMGASLLRLHFHDCFVQGCDASVLLDDTSNFTGEKTAGPNANSIRGFEVIDTIKSQVESLCPGVVSCADILAVAARDSVVALGGASWNVLLGRRDSTTASLSSANSDLPAPFFNLSGLISAFSNKGFTTKELVTLSGAHTIGQAQCTAFRTRIYNESNIDPTYAKSLQANCPSVGGDTNLSPFDVTTPNKFDNAYYINLRNKKGLLHSDQQLFNGVSTDSQVTAYSNNAATFNTDFGNAMIKMGNLSPLTGTSGQIRTNCRKTN

Gene
pnc1
Protein
Nicotinamidase
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
220 amino acids
Function
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway.
Similarity
Belongs to the isochorismatase family.
Mass
24.501 kDa
Sequence
MSFHPALIIVDVQNDFVHPVYISSGESALEVVPVINRLLENDYKWDTVIATKDVHPKDHLSFTTSHSSTPKPSGTVVNIEAYGHVYKQTLWNSHCVENTPGCEFPDSLNGDRIEFVIPKGSDRLVESYSGFYDAIGRDNGLKAILDKKGITDVFIAGVATDICVKETALHARHWYNTYIISEAVKGSSTESHNQAIKDFRDAKIEVISEKDPILQSVRKV

Gene
PNC1
Protein
Nicotinamidase
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
216 amino acids
Function
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate.
Similarity
Belongs to the isochorismatase family.
Mass
24.993 kDa
Sequence
MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK