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PMAA_003450

Gene
PMAA_003450
Protein
Lipoyl synthase, mitochondrial
Organism
Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
Length
425 amino acids
Function
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
Similarity
Belongs to the radical SAM superfamily. Lipoyl synthase family.
Mass
46.515 kDa
Sequence
MAASSTRLRCLYASSSTWKTSPSQSLISLSRRYATTSSAPPTPSDESSSTLPKRRKTTTFKDKLNAGPSFADFVSGNGDSNNAPLDASEAYALETVMIPGPAGRGKKEHTRLPSWLKTPIPDSTNYKRIKKDLRGLKLNTVCEEARCPNISDCWGGSDKSAATATIMLMGDSCTRGCRFCSVKTLRTPGPLDPHEPENTAEALSRWGLGYVVLTSVDRDDLSDGGAHHFAETVIKIKQKAPGILVECLTGDFAGDFDMVALVAKSGLDVYAHNVETVEALTPHVRDRRATFQQSLRVLEAAKRAKPSLITKTSMMLGFGETEDQMWDALRQLRASNVDVVTFGQYMRPTKRHMAVHEYVTPDKFELWRQRALEMGFLYVASGPLVRSSYKAGEAFIENVLKKRRGVGNTPGAEVTTEVPVDALAK