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PLA2G7

Gene
PLA2G7
Protein
Platelet-activating factor acetylhydrolase
Organism
Bos taurus
Length
444 amino acids
Function
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Similarity
Belongs to the AB hydrolase superfamily. Lipase family.
Mass
50.133 kDa
Sequence
MLPSKLHALFCLCTCLALVYPFDWQDLNPVAYIESPAWVSKIQALMAAANIGQSKIPRGNGSYSVGCTDLMFDYTNKGTFLRLYYPSQDDDHSDTLWIPNKEYFLGLSKFLGTHWLVGKIMGLFFGSMTTPAAWNAHLRTGEKYPLIIFSHGLGAFRTIYSAIGIDLASHGFIVAAVEHRDGSASSTYYFKDQSAVEIGNKSWLYLRTLKRGEEEFPLRNEQLRQRAKECSQALSLILDIDHGRPVTNVLDLEFDVEQLKDSIDRDKIAIIGHSFGGATVIQTLSEDQRFRCGIALDAWMFPVGDEVYSRIPQPLFFINSERFQYPSNIIRMKKCFLPDRERKMITIRGSVHQNFVDFTFATSKIIGYLFTLKGDIDSNVAISLSNKASLAFLQKHLGLQKDFDQWDSLVEGEDHNLIPGTNINTTNHQAILQNSTGIERPNLD
Protein
Platelet-activating factor acetylhydrolase: PLA2G7

Gene
PLA2G7
Protein
Platelet-activating factor acetylhydrolase
Organism
Canis lupus familiaris
Length
444 amino acids
Function
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Similarity
Belongs to the AB hydrolase superfamily. Lipase family.
Mass
50.136 kDa
Sequence
MLPPKLHALFCLCSCLTLVHPIDWQDLNPVAHIRSSAWANKIQALMAAASIRQSRIPKGNGSYSVGCTDLMFDYTNKGTFLRLYYPSQEDDHSDTLWIPNKEYFFGLSKYLGTPWLMGKILSFFFGSVTTPANWNSPLRTGEKYPLIVFSHGLGAFRTIYSAIGIDLASHGFIVAAIEHRDGSASATYYFKDQSAAEIGNKSWSYLQELKPGDEEIHVRNEQVQKRAKECSQALNLILDIDHGRPIKNVLDLEFDVEQLKDSIDRDKIAVIGHSFGGATVLQALSEDQRFRCGIALDAWMLPLDDAIYSRIPQPLFFINSERFQFPENIKKMKKCYSPDKERKMITIRGSVHQNFADFTFTTGKIVGYIFTLKGDIDSNVAIDLCNKASLAFLQKHLGLRKDFDQWDSLIEGKDENLMPGTNINITNEHDTLQNSPEAEKSNLD
Protein
Platelet-activating factor acetylhydrolase: PLA2G7

Gene
PLA2G7
Protein
Platelet-activating factor acetylhydrolase
Organism
Homo sapiens
Length
441 amino acids
Function
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Similarity
Belongs to the AB hydrolase superfamily. Lipase family.
Mass
50.077 kDa
Sequence
MVPPKLHVLFCLCGCLAVVYPFDWQYINPVAHMKSSAWVNKIQVLMAAASFGQTKIPRGNGPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNILRLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHRDRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFATGKIIGHMLKLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGTNINTTNQHIMLQNSSGIEKYN
Protein
Platelet-activating factor acetylhydrolase: PLA2G7

Gene
Pla2g7
Protein
Platelet-activating factor acetylhydrolase
Organism
Mus musculus
Length
440 amino acids
Function
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Similarity
Belongs to the AB hydrolase superfamily. Lipase family.
Mass
49.258 kDa
Sequence
MVPLKLQALFCLLCCLPWVHPFHWQDTSSFDFRPSVMFHKLQSVMSAAGSGHSKIPKGNGSYPVGCTDLMFGYGNESVFVRLYYPAQDQGRLDTVWIPNKEYFLGLSIFLGTPSIVGNILHLLYGSLTTPASWNSPLRTGEKYPLIVFSHGLGAFRTIYSAIGIGLASNGFIVATVEHRDRSASATYFFEDQVAAKVENRSWLYLRKVKQEESESVRKEQVQQRAIECSRALSAILDIEHGDPKENVLGSAFDMKQLKDAIDETKIALMGHSFGGATVLQALSEDQRFRCGVALDPWMYPVNEELYSRTLQPLLFINSAKFQTPKDIAKMKKFYQPDKERKMITIKGSVHQNFDDFTFVTGKIIGNKLTLKGEIDSRVAIDLTNKASMAFLQKHLGLQKDFDQWDPLVEGDDENLIPGSPFDAVTQVPAQQHSPGSQTQN
Protein
Platelet-activating factor acetylhydrolase: Pla2g7

Gene
PLA2G7
Protein
Platelet-activating factor acetylhydrolase
Organism
Cavia porcellus
Length
436 amino acids
Function
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Similarity
Belongs to the AB hydrolase superfamily. Lipase family.
Mass
49.063 kDa
Sequence
MAPPKLHTLFCLSGFLALVHPFDWRDLDPVTYIQSSVWIQRIQSELLITSFGHTTIPKGNGPYSVGCTDLMSGYTNQSSFLRLYYPSQDNDFPDALWIPNEEYFQGLTETLGASSFLGKLLKLLYGSVKVPAKWNSPLKTGEKYPLIIFSHGLGAFRSIYSAIGIELASHGFIVAAVEHRDESAAATYYFQDAPAAESGNRSWIYYKVGNLETEERKRQLRQRGEECSQALSWLLSIDEGEPVKNVLDLNFDIQQLKGSLDRSKVAIIGHSFGGATVIQTLSEDQRFRCGIALDPWMFPVGEDVHSKIPQPLFFINSEYFQSANDTKKIEKFYQPQKERKMIAVKGSVHHNFVDFTFATGKIIGQMLSLKGKIDSEVAMDLINKASLAFLQKYLGLDKNFDQWNSLMEGDDENLIPEFTIPTTMQSSTGTEQRNPD
Protein
Platelet-activating factor acetylhydrolase: PLA2G7

Gene
PLA2G7
Protein
Platelet-activating factor acetylhydrolase
Organism
Gallus gallus
Length
422 amino acids
Function
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Similarity
Belongs to the AB hydrolase superfamily. Lipase family.
Mass
47.046 kDa
Sequence
MASLWVRARRVFMKSRASGFSAKAATEMGSGGAEKGYRIPAGKGPHAVGCTDLMTGDAAEGSFLRLYYLSCDDTDTEETPWIPDKEYYQGLSDFLNVYRALGERLFQYYVGSVTCPAKSNAAFKPGEKYPLLVFSHGLGAFRTIYSAICIEMASQGFLVAAVEHRDESASATYFCKKKADSEPEEDQTSGVEKEWIYYRKLRAGEEERCLRHKQVQQRAQECIKALNLILKISSGEEVMNVLNSDFDWNHLKDSVDTSRIAVMGHSFGGATVIESLSKEIRFRCGIALDAWMLPVGDDTYQSSVQQPLLFINSEKFQWAANILKMKKLSSNDTNKKMITIKGSVHQSFPDFTFVSGEIIGKFFKLKGEIDPNEAIDICNHASLAFLQKHLSLKRDFDKWDSLVDGIGPNVISGTNIDLSPTE
Protein
Platelet-activating factor acetylhydrolase: PLA2G7