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PHA1

Gene
PHA1
Protein
Phallacidin proprotein 1
Organism
Amanita phalloides
Length
23 amino acids
Function
Major toxin that belongs to the bicyclic heptapeptides called phallotoxins (PubMed:24613547). Although structurally related to amatoxins, phallotoxins have a different mode of action, which is the stabilization of F-actin (PubMed:24613547). Phallotoxins are poisonous when administered parenterally, but not orally because of poor absorption (PubMed:24613547).
Similarity
Belongs to the MSDIN fungal toxin family.
Mass
2.571 kDa
Fragment
single
Sequence
PAWLVDCPCVGDDINRLLTRGEK